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Cse1l
Gene Detail
Symbol

Name
ID
Cse1l
chromosome segregation 1-like (S. cerevisiae)
MGI:1339951
Synonyms
2610100P18Rik, Capts, Cas, Xpo2
Feature Type
protein coding gene
Genetic Map
Chromosome 2
87.22 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr2:166906040-166946389 bp, + strand
From VEGA annotation of GRCm38

  40350 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:1006  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: exportin-2
Gene Tree: Cse1l

Human
homologs
Human Homolog CSE1L, CSE1 chromosome segregation 1-like (yeast)
NCBI Gene ID 1434
neXtProt AC  NX_P55060
Human Synonyms  CAS, CSE1, XPO2
Human Chr (Location)  20q13; chr20:49046246-49096960 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(47) : Gene trapped(44) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Embryos homozygous for a targeted null mutation die prior to E5.5 of development and are morphologically disorganized and lack identifiable structures.
 
Interactions
Cse1l interacts with 307 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process intracellular protein transport, protein transport, ...
Component cytoplasm, extracellular vesicular exosome, ...
Function protein binding, Ran GTPase binding
External Resources: FuncBase
Expression
Literature Summary: (6 records)
Data Summary: Results (177)    Tissues (59)    Images (26)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 165
Northern blot 12
cDNA source data(159)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(159) cDNA(159)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000001165 (Evidence)
Ensembl Gene ModelENSMUSG00000002718 (Evidence)
Entrez Gene110750 (Evidence)
UniGene22417
DFCITC1575470, TC1679705
DoTSDT.110678381, DT.101385614, DT.493621
NIA Mouse Gene IndexU002844
Consensus CDS ProjectCCDS17092.1
International Mouse Knockout Project StatusCse1l
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000001165 VEGA Gene Model | MGI Sequence Detail 40350 C57BL/6J ±  kb
transcript OTTMUST00000002261 VEGA | MGI Sequence Detail 3641 Not Applicable 
polypeptide OTTMUSP00000001106 VEGA | MGI Sequence Detail 971 Not Applicable 

For the selected sequences
All sequences(66) RefSeq(3) UniProt(11)
Polymorphisms
RFLP(1) : SNPs within 2kb(202 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR011989 Armadillo-like helical
InterPro IPR016024 Armadillo-type fold
InterPro IPR005043 CAS/CSE, C-terminal
InterPro IPR013713 Exportin/Importin, Cse1-like
InterPro IPR001494 Importin-beta, N-terminal
Protein Ontology PR:000005929 exportin-2
References
(Earliest) J:47272 de Miguel M, et al., Cellular apoptosis susceptibility gene capts maps to mouse chromosome 2. Mamm Genome. 1998 May;9(5):411-2
(Latest) J:193640 Lo JC, et al., RAB-like 2 has an essential role in male fertility, sperm intra-flagellar transport, and tail assembly. PLoS Genet. 2012;8(10):e1002969
All references(43)
Other
accession IDs
MGI:1206578, MGI:1917576, MGI:2138744

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory