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Myh3 Gene Detail
Summary
  • Symbol
    Myh3
  • Name
    myosin, heavy polypeptide 3, skeletal muscle, embryonic
  • Synonyms
    MyHC-emb, Myhse, Myhs-e
  • Feature Type
    protein coding gene
  • IDs
    MGI:1339709
    NCBI Gene: 17883
  • Gene Overview
    MyGene.info: MYH3
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:67078300-67102291 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 40.59 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    363 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1339709
protein coding gene Chr11:67078273-67102291 (.)
129S1/SvImJ MGP_129S1SvImJ_G0018485
protein coding gene Chr11:67357583-67382980 (+)
A/J MGP_AJ_G0018454
protein coding gene Chr11:64832357-64859008 (+)
AKR/J MGP_AKRJ_G0018423
protein coding gene Chr11:66775662-66799842 (+)
BALB/cJ MGP_BALBcJ_G0018425
protein coding gene Chr11:65118550-65143049 (+)
C3H/HeJ MGP_C3HHeJ_G0018238
protein coding gene Chr11:66784312-66811475 (+)
C57BL/6NJ MGP_C57BL6NJ_G0018877
protein coding gene Chr11:69390955-69417472 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016521
protein coding gene Chr11:61796237-61820470 (+)
CAST/EiJ MGP_CASTEiJ_G0017794
protein coding gene Chr11:67009685-67033682 (+)
CBA/J MGP_CBAJ_G0018212
protein coding gene Chr11:72437023-72468758 (+)
DBA/2J MGP_DBA2J_G0018321
protein coding gene Chr11:64379738-64404095 (+)
FVB/NJ MGP_FVBNJ_G0018311
protein coding gene Chr11:64041327-64067837 (+)
LP/J MGP_LPJ_G0018393
protein coding gene Chr11:67910171-67937360 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0018335
protein coding gene Chr11:73266262-73292687 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0018918
protein coding gene Chr11:67007636-67031556 (+)
PWK/PhJ MGP_PWKPhJ_G0017568
protein coding gene Chr11:65038685-65063473 (+)
SPRET/EiJ MGP_SPRETEiJ_G0017358
protein coding gene Chr11:66832971-66857882 (+)
WSB/EiJ MGP_WSBEiJ_G0017847
protein coding gene Chr11:66624660-66650773 (+)



Homology
more
  • Human Ortholog
    MYH3, myosin heavy chain 3
  • Vertebrate Orthologs
    8
  • Human Ortholog
    MYH3, myosin heavy chain 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    DA2A, DA2B, DA8, HEMHC, MYHC-EMB, MYHSE1, SMHCE
  • Links
    NCBI Gene ID: 4621
    neXtProt AC: NX_P11055
    UniProt: P11055

  • Chr Location
    17p13.1; chr17:10628526-10679657 (-)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with human MYH3 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000020908 Ensembl Gene Model | MGI Sequence Detail 23992 C57BL/6J ±  kb
transcript ENSMUST00000108689 Ensembl | MGI Sequence Detail 6031 Not Applicable  
polypeptide ENSMUSP00000104329 Ensembl | MGI Sequence Detail 1940 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 37
    Genomic 4
    cDNA 28
    Primer pair 3
    Other 2

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-12754, MGD-MRK-12759, MGI:97262
References
more
  • Summaries
    All 80
    Developmental Gene Expression 39
    Gene Ontology 5
    Phenotypes 9
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:245768 Landry-Truchon K, et al., HOXA5 plays tissue-specific roles in the developing respiratory system. Development. 2017 Oct 01;144(19):3547-3561

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory