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Myh3 Gene Detail
Summary
  • Symbol
    Myh3
  • Name
    myosin, heavy polypeptide 3, skeletal muscle, embryonic
  • Synonyms
    MyHC-emb, Myhse, Myhs-e
  • Feature Type
    protein coding gene
  • IDs
    MGI:1339709
    NCBI Gene: 17883
  • Gene Overview
    MyGene.info: MYH3
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr11:67078300-67102286 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      23987 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 40.59 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    MYH3, myosin heavy chain 3
  • Vertebrate Orthologs
    8
  • Human Ortholog
    MYH3, myosin heavy chain 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    DA2A, DA2B, DA8, HEMHC, MYHC-EMB, MYHSE1, SMHCE
  • Links
    NCBI Gene ID: 4621
    neXtProt AC: NX_P11055
    UniProt: P11055

  • Chr Location
    17p13.1; chr17:10628526-10679657 (-)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with human MYH3 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005920 VEGA Gene Model | MGI Sequence Detail 23987 C57BL/6J ±  kb
transcript OTTMUST00000013182 VEGA | MGI Sequence Detail 6031 Not Applicable  
polypeptide OTTMUSP00000006118 VEGA | MGI Sequence Detail 1940 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    363 from dbSNP Build 142
  • RFLP
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 36
    Genomic 4
    cDNA 27
    Primer pair 3
    Other 2

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-12754, MGD-MRK-12759, MGI:97262
References
more
  • Summaries
    All 78
    Developmental Gene Expression 38
    Gene Ontology 5
    Phenotypes 8
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:243670 Espinoza-Lewis RA, et al., Poly(C)-binding protein 1 (Pcbp1) regulates skeletal muscle differentiation by modulating microRNA processing in myoblasts. J Biol Chem. 2017 Jun 09;292(23):9540-9550

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/14/2017
MGI 6.11
The Jackson Laboratory