S100a11
Gene Detail

Symbol Name ID

S100a11 S100 calcium binding protein A11 (calgizzarin) MGI:1338798

Synonyms

cal, calgizzarin, Emap1, S100a14, S100c

Feature Type

protein coding gene

Genetic Map

Chromosome 3

40.51 cM, cytoband E-F
Detailed Genetic Map ± 1 cM


Mapping data(4)

Sequence Map

Chr3:93520488-93526287 bp, + strand From VEGA annotation of GRCm38   5800 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:55916  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 3 rhesus macaque; 2 cattle; 1 dog; 1 chicken

Protein SuperFamily: S-100 protein
Gene Tree: S100a11

Human homologs

Human Homolog		S100A11, S100 calcium binding protein A11
NCBI Gene ID		6282
neXtProt AC		NX_P31949
Human Synonyms		MLN70, S100C
Human Chr (Location)		1q21; chr1:152004982-152009511 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(15) : Targeted(3) Gene trapped(12)
 

Mice dwith disruptions in this gene display no obvious phenotype abnormalities other than reduced sperm counts in males.

 

Gene Ontology (GO) classifications

All GO classifications: (10 annotations)

Component	cytoplasm, nucleus, ...
Function	calcium-dependent protein binding, calcium ion binding, ...

External Resources: FuncBase

Expression

Literature Summary: (4 records)
Data Summary: Results (41)    Tissues (19)    Images (12)
Theiler Stages: 11, 13, 20, 21, 22, 23, 24, 28

Assay Type	Results
RNA in situ	7
Northern blot	24
RT-PCR	10

cDNA source data(14)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(16) Genomic(1) cDNA(14) Primer pair(1)
Microarray probesets(4)

Other database links

VEGA Gene Model	OTTMUSG00000022126 (Evidence)
Ensembl Gene Model	ENSMUSG00000027907 (Evidence)
Entrez Gene	20195 (Evidence)
DFCI	TC1586698, TC1736567
DoTS	DT.103578298
Consensus CDS Project	CCDS38525.1
International Mouse Knockout Project Status	S100a11

Sequences

Length	Strain/Species
genomic	OTTMUSG00000022126	VEGA Gene Model | MGI Sequence Detail	5800	C57BL/6J
transcript	OTTMUST00000052513	VEGA | MGI Sequence Detail	511	Not Applicable
polypeptide	OTTMUSP00000024913	VEGA | MGI Sequence Detail	98	Not Applicable

All sequences(21) RefSeq(2) UniProt(1)

Polymorphisms

SNPs(24 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR018248	EF-hand
InterPro	IPR018247	EF-Hand 1, calcium-binding site
InterPro	IPR018249	EF-HAND 2
InterPro	IPR011992	EF-hand-like domain
InterPro	IPR013787	S100/CaBP-9k-type, calcium binding, subdomain
InterPro	IPR001751	S100/Calbindin-D9k, conserved site
Protein Ontology	PR:000014404	protein S100-A11

References

(Earliest) J:20657 Kao J, et al., Characterization of a novel tumor-derived cytokine. Endothelial-monocyte activating polypeptide II. J Biol Chem. 1994 Oct 7;269(40):25106-19
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(45)

Other accession IDs

MGD-MRK-19682, MGI:102775, MGI:1353430