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Taf1 Gene Detail
Summary
  • Symbol
    Taf1
  • Name
    TATA-box binding protein associated factor 1
  • Synonyms
    B430306D02Rik, Ccg1, Ccg-1, KAT4, Taf2a
  • Feature Type
    protein coding gene
  • IDs
    MGI:1336878
    NCBI Gene: 270627
  • Gene Overview
    MyGene.info: TAF1
Location & Maps
more
  • Sequence Map
    ChrX:101532734-101601034 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      68301 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome X, 44.29 cM
  • Mapping Data
    16 experiments
Homology
more
  • Human Ortholog
    TAF1, TATA-box binding protein associated factor 1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    TAF1, TATA-box binding protein associated factor 1
    Orthology source: HomoloGene
  • Synonyms
    BA2R, CCG1, CCGS, DYT3, DYT3/TAF1, KAT4, MRXS33, NSCL2, N-TAF1, OF, P250, TAF2A, TAFII250, TAF(II)250, TAFII-250, XDP
  • Links
    NCBI Gene ID: 6872
    neXtProt AC: NX_P21675

  • Chr Location
    Xq13.1; chrX:71366218-71530525 (+)  GRCh38.p2

Human Diseases
more
  • Diseases
    2 with human TAF1 associations

Human Disease Mouse Models
       Dystonia 3, Torsion, X-Linked; DYT3   OMIM: 314250
Mental Retardation, X-Linked, Syndromic 33; MRXS33   OMIM: 300966
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotype references
  • All Mutations and Alleles
    9
  • Gene trapped
    9
  • Incidental Mutations
    APF , CvDC
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000018200 VEGA Gene Model | MGI Sequence Detail 68301 C57BL/6J ±  kb
transcript OTTMUST00000043935 VEGA | MGI Sequence Detail 7210 Not Applicable  
polypeptide OTTMUSP00000019728 VEGA | MGI Sequence Detail 1870 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    119 from dbSNP Build 142
  • RFLP
Protein
Information
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  • UniProt
    5 Sequences
  • Protein Ontology
    PR:000016014 transcription initiation factor TFIID subunit 1
  • EC
  • InterPro Domains
    IPR001487 Bromodomain
    IPR018359 Bromodomain, conserved site
    IPR009067 TAFII-230 TBP-binding
    IPR011177 Transcription initiation factor TFIID subunit 1, animal
    IPR022591 Transcription initiation factor TFIID subunit 1, domain of unknown function
Molecular
Reagents
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  • All nucleic 125
    cDNA 124
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
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MGD-MRK-1796, MGD-MRK-1797, MGI:2147953, MGI:88292
References
more
  • Summaries
    All 59
    Developmental Gene Expression 10
    Gene Ontology 10
    Phenotypes 2
  • Earliest
    J:12527 Derry JM, et al., Localization of the Ccg1 gene on the mouse X Chromosome. Cytogenet Cell Genet. 1989;51:988
  • Latest
    J:221584 Quesnel-Vallieres M, et al., Essential roles for the splicing regulator nSR100/SRRM4 during nervous system development. Genes Dev. 2015 Apr 1;29(7):746-59

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/12/2016
MGI 6.04
The Jackson Laboratory