About   Help   FAQ
Taf1
Gene Detail
 Symbol
Name
ID
Taf1
TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor
MGI:1336878
Synonyms B430306D02Rik, Ccg1, Ccg-1, KAT4, Taf2a
Feature Type protein coding gene
Genetic Map
Chromosome X
44.29 cM
Detailed Genetic Map ± 1 cM


Mapping data(16)
Sequence Map
ChrX:101532734-101601034 bp, + strand
From VEGA annotation of GRCm38

  68301 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:37942  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: transcription initiation factor IID, subunit 1 (TAF1), animal type
Gene Tree: Taf1

Human
homologs
Human Homolog TAF1, TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
NCBI Gene ID 6872
neXtProt AC  NX_P21675
Human Synonyms  BA2R, CCG1, CCGS, DYT3, DYT3/TAF1, KAT4, NSCL2, N-TAF1, OF, P250, TAF2A, TAFII250, TAF(II)250, TAFII-250, XDP
Human Chr (Location)  Xq13.1; chrX:71366239-71530525 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human TAF1
Mutations,
alleles, and
phenotypes
All mutations/alleles(9) : Gene trapped(9)
Incidental mutations (data from APF )
Interactions
Taf1 interacts with 356 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (35 annotations)
Process cell cycle, DNA-templated transcription, initiation, ...
Component MLL1 complex, nucleus, ...
Function ATP binding, DNA binding, ...
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression
Literature Summary: (8 records)
Data Summary: Results (135)    Tissues (80)    Images (9)
Theiler Stages: 15, 17, 19, 21, 23, 25, 28
Assay TypeResults
RNA in situ 103
RT-PCR 32
cDNA source data(122)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(125) cDNA(124) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000018200 (Evidence)
Ensembl Gene ModelENSMUSG00000031314 (Evidence)
Entrez Gene270627 (Evidence)
UniGene261750
DFCITC1578682, TC1606965, TC1624299, TC1634480, TC1676328
DoTSDT.111023924, DT.55281119, DT.60101671, DT.97342492, DT.97351816
NIA Mouse Gene IndexU043776
EC2.3.1.48, 2.7.11.1
Consensus CDS ProjectCCDS41080.1
International Mouse Knockout Project StatusTaf1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000018200 VEGA Gene Model | MGI Sequence Detail 68301 C57BL/6J ±  kb
transcript OTTMUST00000043935 VEGA | MGI Sequence Detail 7210 Not Applicable 
polypeptide OTTMUSP00000019728 VEGA | MGI Sequence Detail 1870 Not Applicable 

For the selected sequences
All sequences(72) RefSeq(15) UniProt(4)
Polymorphisms RFLP(2) : SNPs within 2kb(121 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001487 Bromodomain
InterPro IPR018359 Bromodomain, conserved site
InterPro IPR009067 TAFII-230 TBP-binding
InterPro IPR011177 Transcription initiation factor TFIID subunit 1, animal
InterPro IPR022591 Transcription initiation factor TFIID subunit 1, domain of unknown function
Protein Ontology PR:000016014 transcription initiation factor TFIID subunit 1
References (Earliest) J:12527 Derry JM, et al., Localization of the Ccg1 gene on the mouse X Chromosome. Cytogenet Cell Genet. 1989;51:988
(Latest) J:209112 Shimizu H, et al., The AERO system: a 3D-like approach for recording gene expression patterns in the whole mouse embryo. PLoS One. 2013;8(10):e75754
All references(61)
Other
accession IDs
MGD-MRK-1796, MGD-MRK-1797, MGI:2147953, MGI:88292

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/19/2014
MGI 5.19
The Jackson Laboratory