Taf1
Gene Detail

Symbol Name ID

Taf1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor MGI:1336878

Synonyms

B430306D02Rik, Ccg1, Ccg-1, KAT4, Taf2a

Feature Type

protein coding gene

Genetic Map

Chromosome X

44.29 cM
Detailed Genetic Map ± 1 cM


Mapping data(17)

Sequence Map

ChrX:101532734-101601034 bp, + strand From VEGA annotation of GRCm38   68301 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:37942  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: transcription initiation factor IID, subunit 1 (TAF1), animal type
Gene Tree: Taf1

Human homologs

Human Homolog		TAF1, TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
NCBI Gene ID		6872
neXtProt AC		NX_P21675
Human Synonyms		BA2R, CCG1, CCGS, DYT3, DYT3/TAF1, KAT4, NSCL2, N-TAF1, OF, P250, TAF2A, TAFII250, XDP
Human Chr (Location)		Xq13.1; chrX:70586114-70685855 (+)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human TAF1

Alleles and phenotypes

All alleles(9) : Gene trapped(9)

Gene Ontology (GO) classifications

All GO classifications: (34 annotations)

Process	cell cycle, DNA-dependent transcription, initiation, ...
Component	MLL1 complex, nucleus, ...
Function	ATP binding, DNA binding, ...

This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase

Expression

Literature Summary: (7 records)
Data Summary: Results (135)    Tissues (80)    Images (9)
Theiler Stages: 15, 17, 19, 21, 23, 25, 28

Assay Type	Results
RNA in situ	103
RT-PCR	32

cDNA source data(122)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(125) cDNA(124) Primer pair(1)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000018200 (Evidence)
Ensembl Gene Model	ENSMUSG00000031314 (Evidence)
Entrez Gene	270627 (Evidence)
UniGene	261750
DFCI	TC1578682, TC1606965, TC1624299, TC1634480, TC1676328
DoTS	DT.55281119, DT.60101671, DT.97342492, DT.97351816
NIA Mouse Gene Index	U043776
EC	2.7.11.1
Consensus CDS Project	CCDS41080.1
International Mouse Knockout Project Status	Taf1

Sequences

Length	Strain/Species
genomic	OTTMUSG00000018200	VEGA Gene Model | MGI Sequence Detail	68301	C57BL/6J
transcript	OTTMUST00000043935	VEGA | MGI Sequence Detail	7210	Not Applicable
polypeptide	OTTMUSP00000019728	VEGA | MGI Sequence Detail	1870	Not Applicable

All sequences(54) RefSeq(3) UniProt(3)

Polymorphisms

RFLP(2) : SNPs(112 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR001487	Bromodomain
InterPro	IPR018359	Bromodomain, conserved site
InterPro	IPR009067	TAFII-230 TBP-binding
InterPro	IPR011177	Transcription initiation factor TFIID subunit 1, animal
InterPro	IPR022591	Transcription initiation factor TFIID subunit 1, domain of unknown function
Protein Ontology	PR:000016014	transcription initiation factor TFIID subunit 1

References

(Earliest) J:12527 Derry JM, et al., Localization of the Ccg1 gene on the mouse X Chromosome. Cytogenet Cell Genet. 1989;51:988
(Latest) J:187159 Jambaldorj J, et al., Sustained expression of a neuron-specific isoform of the Taf1 gene in development stages and aging in mice. Biochem Biophys Res Commun. 2012 Aug 24;425(2):273-7
All references(59)

Other accession IDs

MGD-MRK-1796, MGD-MRK-1797, MGI:2147953, MGI:88292