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Taf1
Gene Detail
Symbol

Name
ID
Taf1
TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor
MGI:1336878
Synonyms
B430306D02Rik, Ccg1, Ccg-1, KAT4, Taf2a
Feature Type
protein coding gene
Genetic Map
Chromosome X
44.29 cM
Detailed Genetic Map ± 1 cM


Mapping data(16)
Sequence Map
ChrX:101532734-101601034 bp, + strand
From VEGA annotation of GRCm38

  68301 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:37942  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: TAF1
Protein SuperFamily: transcription initiation factor IID, subunit 1 (TAF1), animal type
Gene Tree: Taf1

Human
homologs
TAF1, TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 6872
neXtProt AC: NX_P21675

Human Synonyms: BA2R, CCG1, CCGS, DYT3, DYT3/TAF1, KAT4, NSCL2, N-TAF1, OF, P250, TAF2A, TAFII250, TAF(II)250, TAFII-250, XDP

Human Chr (Location): Xq13.1; chrX:71366218-71530525 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human TAF1

Mutations,
alleles, and
phenotypes
All mutations/alleles(9) : Gene trapped(9)
Incidental mutations (data from APF , CvDC )
Interactions
Taf1 interacts with 355 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (35 annotations)
Process cell cycle, DNA-templated transcription, initiation, ...
Component MLL1 complex, nucleoplasm, ...
Function ATP binding, DNA binding, ...
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression
Literature Summary: (8 records)
Data Summary: Results (135)    Tissues (81)    Images (9)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 103
RT-PCR 32
cDNA source data(122)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase taf1    NEW 
Molecular
reagents
All nucleic(125) cDNA(124) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000018200 (Evidence)
Ensembl Gene Model ENSMUSG00000031314 (Evidence)
Entrez Gene 270627 (Evidence)
UniGene 261750
DFCI TC1676328, TC1634480, TC1624299, TC1606965, TC1578682
DoTS DT.111023924, DT.55281119, DT.97351816, DT.97342492, DT.60101671
NIA Mouse Gene Index U043776
EC 2.3.1.48, 2.7.11.1
Consensus CDS Project CCDS41080.1
International Mouse Phenotyping Consortium Status Taf1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000018200 VEGA Gene Model | MGI Sequence Detail 68301 C57BL/6J ±  kb
transcript OTTMUST00000043935 VEGA | MGI Sequence Detail 7210 Not Applicable 
polypeptide OTTMUSP00000019728 VEGA | MGI Sequence Detail 1870 Not Applicable 

For the selected sequences
All sequences(76) RefSeq(18) UniProt(5)
Polymorphisms
RFLP(2) : SNPs within 2kb(121 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001487 Bromodomain
InterPro IPR018359 Bromodomain, conserved site
InterPro IPR009067 TAFII-230 TBP-binding
InterPro IPR011177 Transcription initiation factor TFIID subunit 1, animal
InterPro IPR022591 Transcription initiation factor TFIID subunit 1, domain of unknown function
Protein Ontology PR:000016014 transcription initiation factor TFIID subunit 1
References
(Earliest) J:12527 Derry JM, et al., Localization of the Ccg1 gene on the mouse X Chromosome. Cytogenet Cell Genet. 1989;51:988
(Latest) J:209112 Shimizu H, et al., The AERO system: a 3D-like approach for recording gene expression patterns in the whole mouse embryo. PLoS One. 2013;8(10):e75754
All references(60)
Other
accession IDs
MGD-MRK-1796, MGD-MRK-1797, MGI:2147953, MGI:88292

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory