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Uap1
Gene Detail
Symbol

Name
ID
Uap1
UDP-N-acetylglucosamine pyrophosphorylase 1
MGI:1334459
Synonyms
AgX, AGX1, ESTM38, SPAG2
Feature Type
protein coding gene
Genetic Map
Chromosome 1
76.84 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr1:170141938-170174957 bp, - strand
From VEGA annotation of GRCm38

  33020 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:2342  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: UAP1
Gene Tree: Uap1

Human
homologs
UAP1, UDP-N-acetylglucosamine pyrophosphorylase 1
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 6675
neXtProt AC: NX_Q16222

Human Synonyms: AGX, AGX1, AGX2, SPAG2

Human Chr (Location): 1q23.3; chr1:162561506-162599843 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(3) Targeted(2)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Uap1 interacts with 90 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process metabolic process, UDP-N-acetylglucosamine metabolic process
Component cytoplasm, cytosol, ...
Function carbohydrate binding, identical protein binding, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (94)    Tissues (94)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 94
cDNA source data(76)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase uap1 ; ZFIN uap1    NEW 
Molecular
reagents
All nucleic(77) cDNA(76) Primer pair(1)
Microarray probesets(7)
Other database
links
VEGA Gene Model OTTMUSG00000023030 (Evidence)
Ensembl Gene Model ENSMUSG00000026670 (Evidence)
Entrez Gene 107652 (Evidence)
UniGene 27969
DFCI TC1588683, TC1616677, TC1574245, TC1736724, TC1732193
DoTS DT.94369833, DT.94351559, DT.91320756, DT.492115
NIA Mouse Gene Index U022031
EC 2.7.7.83, 2.7.7.23
PDB 1VM8
Consensus CDS Project CCDS15467.1
International Mouse Phenotyping Consortium Status Uap1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023030 VEGA Gene Model | MGI Sequence Detail 33020 C57BL/6J ±  kb
transcript OTTMUST00000055485 VEGA | MGI Sequence Detail 2287 Not Applicable 
polypeptide OTTMUSP00000026567 VEGA | MGI Sequence Detail 522 Not Applicable 

For the selected sequences
All sequences(91) RefSeq(16) UniProt(3)
Polymorphisms
SNPs within 2kb(475 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002618 UTP--glucose-1-phosphate uridylyltransferase
Protein Ontology PR:000016948 UDP-N-acetylhexosamine pyrophosphorylase
References
(Earliest) J:52606 Eddleston J, et al., Physical and transcriptional map of a 3-Mb region of mouse chromosome 1 containing the gene for the neural tube defect mutant loop-tail (Lp). Genomics. 1999 Mar 1;56(2):149-59
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(33)
Other
accession IDs
MGI:2138098

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/30/2015
MGI 5.22
The Jackson Laboratory