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Uap1 Gene Detail
Summary
  • Symbol
    Uap1
  • Name
    UDP-N-acetylglucosamine pyrophosphorylase 1
  • Synonyms
    AgX, AGX1, ESTM38, SPAG2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1334459
    NCBI Gene: 107652
  • Gene Overview
    MyGene.info: UAP1
Location & Maps
more
  • Sequence Map
    Chr1:170141938-170174957 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      33020 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 76.84 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    UAP1, UDP-N-acetylglucosamine pyrophosphorylase 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    UAP1, UDP-N-acetylglucosamine pyrophosphorylase 1
    Orthology source: HomoloGene
  • Synonyms
    AGX, AGX1, AGX2, SPAG2
  • Links
    NCBI Gene ID: 6675
    neXtProt AC: NX_Q16222

  • Chr Location
    1q23.3; chr1:162561506-162599843 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 2342
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: UAP1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    5 phenotype references
  • All Mutations and Alleles
    7
  • Chemically induced (other)
    2
  • Gene trapped
    3
  • Targeted
    2
  • Genomic Mutations
    2 involving Uap1
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023030 VEGA Gene Model | MGI Sequence Detail 33020 C57BL/6J ±  kb
transcript OTTMUST00000055485 VEGA | MGI Sequence Detail 2287 Not Applicable  
polypeptide OTTMUSP00000026567 VEGA | MGI Sequence Detail 522 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    466 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 77
    cDNA 76
    Primer pair 1

    Microarray probesets 7
Other
Accession IDs
less
MGI:2138098
References
more
  • Summaries
    All 32
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 5
  • Earliest
    J:52606 Eddleston J, et al., Physical and transcriptional map of a 3-Mb region of mouse chromosome 1 containing the gene for the neural tube defect mutant loop-tail (Lp). Genomics. 1999 Mar 1;56(2):149-59
  • Latest
    J:226997 Bebee TW, et al., The splicing regulators Esrp1 and Esrp2 direct an epithelial splicing program essential for mammalian development. Elife. 2015;4

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
06/22/2016
MGI 6.04
The Jackson Laboratory