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Sprr2f Gene Detail
Summary
  • Symbol
    Sprr2f
  • Name
    small proline-rich protein 2F
  • Feature Type
    protein coding gene
  • IDs
    MGI:1330349
    NCBI Gene: 20760
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:92365187-92366442 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 40.14 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    36 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1330349
protein coding gene Chr3:92365187-92366442 (+)
129S1/SvImJ MGP_129S1SvImJ_G0027491
protein coding gene Chr3:92808164-92809419 (+)
A/J MGP_AJ_G0027458
protein coding gene Chr3:89887678-89888933 (+)
AKR/J MGP_AKRJ_G0027423
protein coding gene Chr3:91989749-91991004 (+)
BALB/cJ MGP_BALBcJ_G0027467
protein coding gene Chr3:89698781-89700038 (+)
C3H/HeJ MGP_C3HHeJ_G0027206
protein coding gene Chr3:92214399-92215654 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027910
protein coding gene Chr3:96343881-96345136 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0025261
protein coding gene Chr3:86529765-86531102 (+)
CAST/EiJ MGP_CASTEiJ_G0026654
protein coding gene Chr3:91624181-91625462 (+)
CBA/J MGP_CBAJ_G0027181
protein coding gene Chr3:99639104-99640359 (+)
DBA/2J MGP_DBA2J_G0027318
protein coding gene Chr3:89207995-89209250 (+)
FVB/NJ MGP_FVBNJ_G0027286
protein coding gene Chr3:87374116-87375371 (+)
LP/J MGP_LPJ_G0027427
protein coding gene Chr3:94026804-94028059 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0027310
protein coding gene Chr3:105887500-105888755 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027969
protein coding gene Chr3:91719619-91720874 (+)
PWK/PhJ MGP_PWKPhJ_G0026387
protein coding gene Chr3:89096092-89097346 (+)
SPRET/EiJ MGP_SPRETEiJ_G0026206
protein coding gene Chr3:90045933-90047377 (+)
WSB/EiJ MGP_WSBEiJ_G0026736
protein coding gene Chr3:92113482-92114737 (+)



Homology
less
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    1
  • Radiation induced
    1
  • Targeted
    3
  • Genomic Mutations
    2 involving Sprr2f
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 20760 NCBI Gene Model | MGI Sequence Detail 1256 C57BL/6J ±  kb
transcript NM_011472 RefSeq | MGI Sequence Detail 609 C57BL/6  
polypeptide O70557 UniProt | EBI | MGI Sequence Detail 76 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR029142 Small proline-rich protein 2
    IPR026075 Small proline-rich protein/late cornified envelope protein
Molecular
Reagents
less
  • All nucleic 12
    Genomic 8
    cDNA 4

    Microarray probesets 3
References
more
  • Summaries
    All 32
    Developmental Gene Expression 6
    Diseases 1
    Gene Ontology 5
    Phenotypes 6
  • Earliest
    J:113697 Gibbs S, et al., Molecular characterization and evolution of the SPRR family of keratinocyte differentiation markers encoding small proline-rich proteins. Genomics. 1993 Jun;16(3):630-7
  • Latest
    J:243411 Rutledge EA, et al., Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development. Development. 2017 Sep 01;144(17):3177-3188

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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Funding Information
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last database update
06/11/2019
MGI 6.14
The Jackson Laboratory