Vamp3
Gene Detail

Symbol Name ID

Vamp3 vesicle-associated membrane protein 3 MGI:1321389

Synonyms

ceb, cellubrevin, D130027G05Rik, VAMP-3

Feature Type

protein coding gene

Genetic Map

Chromosome 4

81.53 cM, cytoband E1
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr4:151047300-151057963 bp, - strand From VEGA annotation of GRCm38   10664 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:3511  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 chicken; 1 zebrafish

Protein SuperFamily: synaptobrevin
Gene Tree: Vamp3

Human homologs

Human Homolog		VAMP3, vesicle-associated membrane protein 3
NCBI Gene ID		9341
neXtProt AC		NX_Q15836
Human Synonyms		CEB
Human Chr (Location)		1p36.23; chr1:7831329-7841492 (+)  GRCh37.p10

Alleles and phenotypes

All alleles(8) : Targeted(5) Gene trapped(3)
 

Homozygotes for a targeted null mutation lack vesicle-associated membrane protein 3 but are apparently normal.

 

Gene Ontology (GO) classifications

All GO classifications: (31 annotations)

Process	calcium ion-dependent exocytosis, Golgi to plasma membrane protein transport, ...
Component	apical plasma membrane, cell junction, ...
Function	protein binding, SNARE binding, ...

External Resources: FuncBase

Expression

Literature Summary: (4 records)
Data Summary: Results (11)    Tissues (6)    Images (2)
Theiler Stages: 11, 13, 21, 26, 28

Assay Type	Results
Immunohistochemistry	2
RNA in situ	2
Western blot	7

cDNA source data(11)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(11) cDNA(11)
Microarray probesets(8)

Other database links

VEGA Gene Model	OTTMUSG00000010239 (Evidence)
Ensembl Gene Model	ENSMUSG00000028955 (Evidence)
Entrez Gene	22319 (Evidence)
DFCI	TC1572593, TC1624816
DoTS	DT.55100666, DT.91335672
NIA Mouse Gene Index	U025825
Consensus CDS Project	CCDS18979.1
International Mouse Knockout Project Status	Vamp3

Sequences

Length	Strain/Species
genomic	OTTMUSG00000010239	VEGA Gene Model | MGI Sequence Detail	10664	C57BL/6J
transcript	OTTMUST00000023797	VEGA | MGI Sequence Detail	2120	Not Applicable
polypeptide	OTTMUSP00000010900	VEGA | MGI Sequence Detail	103	Not Applicable

All sequences(36) RefSeq(2) UniProt(2)

Polymorphisms

SNPs(78 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR001388	Synaptobrevin
InterPro	IPR016444	Synaptobrevin, metazoa/fungi
Protein Ontology	PR:000017250	vesicle-associated membrane protein 3

References

(Earliest) J:34570 Martin S, et al., The glucose transporter (GLUT-4) and vesicle-associated membrane protein-2 (VAMP-2) are segregated from recycling endosomes in insulin-sensitive cells. J Cell Biol. 1996 Aug;134(3):625-35
(Latest) J:192579 Fang Q, et al., Juxtamembrane tryptophans of synaptobrevin 2 control the process of membrane fusion. FEBS Lett. 2013 Jan 4;587(1):67-72
All references(58)

Other accession IDs

MGI:2444833