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Kcnj16
Gene Detail
 Symbol
Name
ID
Kcnj16
potassium inwardly-rectifying channel, subfamily J, member 16
MGI:1314842
Synonyms 6430410F18Rik, Kir5.1
Feature Type protein coding gene
Genetic Map
Chromosome 11
75.01 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr11:110968033-111027968 bp, + strand
From VEGA annotation of GRCm38

  59936 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:23112  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: G protein-activated inward rectifier potassium channel
Gene Tree: Kcnj16

Human
homologs
Human Homolog KCNJ16, potassium inwardly-rectifying channel, subfamily J, member 16
NCBI Gene ID 3773
neXtProt AC  NX_Q9NPI9
Human Synonyms  BIR9, KIR5.1
Human Chr (Location)  17q24.3; chr17:70075207-70135608 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Targeted(5)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele exhibit abnormal neuron response to ammonium chloride withdrawal and carbon dioxide treatment.
 
Interactions
Kcnj16 interacts with 247 markers (Mir1b, Mir7-1, Mir9-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (13 annotations)
Process cellular potassium ion transport, ion transport, ...
Component integral component of membrane, membrane, ...
Function inward rectifier potassium channel activity, voltage-gated ion channel activity
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (33)    Tissues (27)    Images (6)
Theiler Stages: 23, 25, 26, 27, 28
Assay TypeResults
RNA in situ 30
RT-PCR 3
cDNA source data(51)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(52) cDNA(51) Primer pair(1)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000003322 (Evidence)
Ensembl Gene ModelENSMUSG00000051497 (Evidence)
Entrez Gene16517 (Evidence)
UniGene30176
DFCITC1579766, TC1594791, TC1744343, TC1747377
DoTSDT.101720052, DT.60100945, DT.87068305, DT.94205425, DT.97359927, DT.97404066
NIA Mouse Gene IndexU013506
Consensus CDS ProjectCCDS25593.1
International Mouse Knockout Project StatusKcnj16
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000003322 VEGA Gene Model | MGI Sequence Detail 59936 C57BL/6J ±  kb
transcript OTTMUST00000006978 VEGA | MGI Sequence Detail 3671 Not Applicable 
polypeptide OTTMUSP00000003313 VEGA | MGI Sequence Detail 419 Not Applicable 

For the selected sequences
All sequences(66) RefSeq(10) UniProt(4)
Polymorphisms RFLP(1) : SNPs within 2kb(660 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR014756 Immunoglobulin E-set
InterPro IPR016449 Potassium channel, inwardly rectifying, Kir
InterPro IPR008061 Potassium channel, inwardly rectifying, Kir5
InterPro IPR013518 Potassium channel, inwardly rectifying, Kir, cytoplasmic
Protein Ontology PR:000002055 inward rectifier potassium channel 16
References (Earliest) J:51106 Mouri T, et al., Assignment of mouse inwardly rectifying potassium channel Kcnj16 to the distal region of mouse chromosome 11. Genomics. 1998 Nov 15;54(1):181-2
(Latest) J:203001 Zaika OL, et al., Direct inhibition of basolateral Kir4.1/5.1 and Kir4.1 channels in the cortical collecting duct by dopamine. Am J Physiol Renal Physiol. 2013 Nov;305(9):F1277-87
All references(44)
Other
accession IDs
MGI:2144072, MGI:2442290

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory