Cyp2c39
Gene Detail

Symbol Name ID

Cyp2c39 cytochrome P450, family 2, subfamily c, polypeptide 39 MGI:1306818

Feature Type

protein coding gene

Genetic Map

Chromosome 19

34.15 cM, cytoband C3
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr19:39510862-39568529 bp, + strand From VEGA annotation of GRCm38   57668 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:117948  Vertebrate Homology Class
1 human; 3 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 2 chicken

Protein SuperFamily: cytochrome P450 CYP2D6
Gene Tree: Cyp2c39

Human homologs

Human Homolog		CYP2C8, cytochrome P450, family 2, subfamily C, polypeptide 8
NCBI Gene ID		1558
neXtProt AC		NX_P10632
Human Synonyms		CPC8, CYPIIC8, MP-12/MP-20
Human Chr (Location)		10q23.33; chr10:96796529-96829254 (-)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human CYP2C8

Alleles and phenotypes

All alleles(2) : Targeted(2)

Gene Ontology (GO) classifications

All GO classifications: (16 annotations)

Process	oxidation-reduction process
Component	endoplasmic reticulum, intracellular membrane-bounded organelle, ...
Function	aromatase activity, caffeine oxidase activity, ...

External Resources: FuncBase

Expression

Literature Summary: (1 records)
cDNA source data(8)
External Resources: GEO   ArrayExpress

Molecular reagents

All nucleic(8) cDNA(8)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000028407 (Evidence)
Ensembl Gene Model	ENSMUSG00000025003 (Evidence)
Entrez Gene	13098 (Evidence)
UniGene	42101
DFCI	TC1598384
DoTS	DT.487057
NIA Mouse Gene Index	U019434
EC	1.14.14.1
Consensus CDS Project	CCDS29795.1
International Mouse Knockout Project Status	Cyp2c39

Sequences

Length	Strain/Species
genomic	OTTMUSG00000028407	VEGA Gene Model | MGI Sequence Detail	57668	C57BL/6J
transcript	OTTMUST00000070386	VEGA | MGI Sequence Detail	1817	Not Applicable
polypeptide	OTTMUSP00000035863	VEGA | MGI Sequence Detail	490	Not Applicable

All sequences(18) RefSeq(2) UniProt(2)

Polymorphisms

SNPs(259 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR001128	Cytochrome P450
InterPro	IPR017972	Cytochrome P450, conserved site
InterPro	IPR002401	Cytochrome P450, E-class, group I
Protein Ontology	PR:000006228	cytochrome P450 2C39

References

(Earliest) J:49570 Luo G, et al., Cloning and expression of murine CYP2Cs and their ability to metabolize arachidonic acid. Arch Biochem Biophys. 1998 Sep 1;357(1):45-57
(Latest) J:193325 Boj SF, et al., Diabetes risk gene and Wnt effector Tcf7l2/TCF4 controls hepatic response to perinatal and adult metabolic demand. Cell. 2012 Dec 21;151(7):1595-607
All references(27)