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Cyp2c39 Gene Detail
Summary
  • Symbol
    Cyp2c39
  • Name
    cytochrome P450, family 2, subfamily c, polypeptide 39
  • Feature Type
    protein coding gene
  • IDs
    MGI:1306818
    NCBI Gene: 13098
  • Gene Overview
    MyGene.info: CYP2C8
Location & Maps
more
  • Sequence Map
    Chr19:39510862-39568529 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      57668 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    CYP2C8, cytochrome P450 family 2 subfamily C member 8
  • Vertebrate Orthologs
    7
  • Human Ortholog
    CYP2C8, cytochrome P450 family 2 subfamily C member 8
    Orthology source: HomoloGene
  • Synonyms
    CPC8, CYPIIC8, MP-12/MP-20
  • Links
    NCBI Gene ID: 1558
    neXtProt AC: NX_P10632

  • Chr Location
    10q23.33; chr10:95036772-95069498 (-)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human CYP2C8 associations

Human Disease Mouse Models
       Cytochrome P450, Subfamily IIC, Polypeptide 8; CYP2C8   OMIM: 601129
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000028407 VEGA Gene Model | MGI Sequence Detail 57668 C57BL/6J ±  kb
transcript OTTMUST00000070386 VEGA | MGI Sequence Detail 1817 Not Applicable  
polypeptide OTTMUSP00000035863 VEGA | MGI Sequence Detail 490 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    340 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 8
    cDNA 8

    Microarray probesets 3
References
more
  • Summaries
    All 25
    Developmental Gene Expression 1
    Gene Ontology 6
    Phenotypes 2
  • Earliest
    J:49570 Luo G, et al., Cloning and expression of murine CYP2Cs and their ability to metabolize arachidonic acid. Arch Biochem Biophys. 1998 Sep 1;357(1):45-57
  • Latest
    J:193325 Boj SF, et al., Diabetes risk gene and Wnt effector Tcf7l2/TCF4 controls hepatic response to perinatal and adult metabolic demand. Cell. 2012 Dec 21;151(7):1595-607

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory