About   Help   FAQ
Cyp2c39
Gene Detail
Symbol

Name
ID
Cyp2c39
cytochrome P450, family 2, subfamily c, polypeptide 39
MGI:1306818
Feature Type
protein coding gene
Genetic Map
Chromosome 19
34.15 cM, cytoband C3
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr19:39510862-39568529 bp, + strand
From VEGA annotation of GRCm38

  57668 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:117948  Vertebrate Homology Class
1 human; 3 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque

Protein SuperFamily: cytochrome P450 CYP2D6
Gene Tree: Cyp2c39

Human
homologs
Human Homolog CYP2C8, cytochrome P450, family 2, subfamily C, polypeptide 8
NCBI Gene ID 1558
neXtProt AC  NX_P10632
Human Synonyms  CPC8, CYPIIC8, MP-12/MP-20
Human Chr (Location)  10q23.33; chr10:95036772-95069497 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human CYP2C8
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Cyp2c39 interacts with 108 markers (Mir1a-1, Mir1a-2, Mir9-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process oxidation-reduction process
Component endoplasmic reticulum, intracellular membrane-bounded organelle, ...
Function aromatase activity, caffeine oxidase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
cDNA source data(8)
External Resources: GEO   Expression Atlas
Molecular
reagents
All nucleic(8) cDNA(8)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000028407 (Evidence)
Ensembl Gene ModelENSMUSG00000025003 (Evidence)
Entrez Gene13098 (Evidence)
UniGene42101
DFCITC1598384
DoTSDT.487057
NIA Mouse Gene IndexU019434
EC1.14.14.1
Consensus CDS ProjectCCDS29795.1
International Mouse Knockout Project StatusCyp2c39
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000028407 VEGA Gene Model | MGI Sequence Detail 57668 C57BL/6J ±  kb
transcript OTTMUST00000070386 VEGA | MGI Sequence Detail 1817 Not Applicable 
polypeptide OTTMUSP00000035863 VEGA | MGI Sequence Detail 490 Not Applicable 

For the selected sequences
All sequences(18) RefSeq(2) UniProt(2)
Polymorphisms
SNPs within 2kb(351 from dbSNP Build 137)    SNPs within 2kb including multiple locations(357)
Protein-related
information
ResourceIDDescription
InterPro IPR001128 Cytochrome P450
InterPro IPR017972 Cytochrome P450, conserved site
InterPro IPR002401 Cytochrome P450, E-class, group I
Protein Ontology PR:000006228 cytochrome P450 2C39
References
(Earliest) J:49570 Luo G, et al., Cloning and expression of murine CYP2Cs and their ability to metabolize arachidonic acid. Arch Biochem Biophys. 1998 Sep 1;357(1):45-57
(Latest) J:193325 Boj SF, et al., Diabetes risk gene and Wnt effector Tcf7l2/TCF4 controls hepatic response to perinatal and adult metabolic demand. Cell. 2012 Dec 21;151(7):1595-607
All references(27)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
10/08/2014
MGI 5.20
The Jackson Laboratory