About   Help   FAQ
Cyp2c39 Gene Detail
Summary
  • Symbol
    Cyp2c39
  • Name
    cytochrome P450, family 2, subfamily c, polypeptide 39
  • Feature Type
    protein coding gene
  • IDs
    MGI:1306818
    NCBI Gene: 13098
  • Gene Overview
    MyGene.info: CYP2C8
  • Alliance
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:39510862-39568529 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 19, 34.15 cM, cytoband C3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    340 from dbSNP Build 142
  • Strain Annotations
    15
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1306818
protein coding gene Chr19:39510822-39568529 (.)
129S1/SvImJ MGP_129S1SvImJ_G0025102
protein coding gene Chr19:38630184-38680584 (+)
A/J MGP_AJ_G0025078
protein coding gene Chr19:36710666-36761346 (+)
AKR/J MGP_AKRJ_G0025046
protein coding gene Chr19:37937339-37999614 (+)
BALB/cJ MGP_BALBcJ_G0025076
protein coding gene Chr19:36854724-36911567 (+)
C3H/HeJ MGP_C3HHeJ_G0024835
protein coding gene Chr19:38040111-38109286 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025517
protein coding gene Chr19:39660264-39719547 (+)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0024301
protein coding gene Chr19:37844879-37909115 (+)
CBA/J MGP_CBAJ_G0024812
protein coding gene Chr19:41576560-41659251 (+)
DBA/2J MGP_DBA2J_G0024944
protein coding gene Chr19:36570245-36634780 (+)
FVB/NJ MGP_FVBNJ_G0024905
protein coding gene Chr19:36399113-36449055 (+)
LP/J MGP_LPJ_G0025030
protein coding gene Chr19:38657827-38732332 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024936
protein coding gene Chr19:41291302-41346267 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025575
protein coding gene Chr19:38052133-38109783 (+)
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0023853
protein coding gene Chr19:36888724-36953898 (+)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    CYP2C8, cytochrome P450 family 2 subfamily C member 8
  • Vertebrate Orthologs
    7
  • Human Ortholog
    CYP2C8, cytochrome P450 family 2 subfamily C member 8
    Orthology source: HomoloGene
  • Synonyms
    CPC8, CYP2C8DM, CYPIIC8, MP-12/MP-20
  • Links
    NCBI Gene ID: 1558
    neXtProt AC: NX_P10632
    UniProt: P10632

  • Chr Location
    10q23.33; chr10:95036772-95069512 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000025003 Ensembl Gene Model | MGI Sequence Detail 57668 C57BL/6J ±  kb
transcript ENSMUST00000025968 Ensembl | MGI Sequence Detail 1817 Not Applicable  
polypeptide ENSMUSP00000025968 Ensembl | MGI Sequence Detail 490 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 8
    cDNA 8

    Microarray probesets 3
References
more
  • Summaries
    All 26
    Developmental Gene Expression 1
    Gene Ontology 7
    Phenotypes 2
  • Earliest
    J:49570 Luo G, et al., Cloning and expression of murine CYP2Cs and their ability to metabolize arachidonic acid. Arch Biochem Biophys. 1998 Sep 1;357(1):45-57
  • Latest
    J:193325 Boj SF, et al., Diabetes risk gene and Wnt effector Tcf7l2/TCF4 controls hepatic response to perinatal and adult metabolic demand. Cell. 2012 Dec 21;151(7):1595-607

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/13/2018
MGI 6.13
The Jackson Laboratory