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Cyp2c39
Gene Detail
Symbol

Name
ID
Cyp2c39
cytochrome P450, family 2, subfamily c, polypeptide 39
MGI:1306818
Feature Type
protein coding gene
Genetic Map
Chromosome 19
34.15 cM, cytoband C3
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr19:39510862-39568529 bp, + strand
From VEGA annotation of GRCm38

  57668 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:117948  Vertebrate Homology Class
1 human; 3 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque

HCOP human homology predictions: CYP2C8
Protein SuperFamily: cytochrome P450 CYP2D6
Gene Tree: Cyp2c39

Human
homologs
CYP2C8, cytochrome P450, family 2, subfamily C, polypeptide 8
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 1558
neXtProt AC: NX_P10632

Human Synonyms: CPC8, CYPIIC8, MP-12/MP-20

Human Chr (Location): 10q23.33; chr10:95036772-95069498 (-)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human CYP2C8

Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Cyp2c39 interacts with 108 markers (Mir1a-1, Mir1a-2, Mir9-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (22 annotations)
Process epoxygenase P450 pathway, exogenous drug catabolic process, ...
Component cytoplasm, endoplasmic reticulum, ...
Function arachidonic acid epoxygenase activity, aromatase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
cDNA source data(8)
Other mouse links: GEO   Expression Atlas
Molecular
reagents
All nucleic(8) cDNA(8)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000028407 (Evidence)
Ensembl Gene Model ENSMUSG00000025003 (Evidence)
Entrez Gene 13098 (Evidence)
UniGene 42101
DFCI TC1598384
DoTS DT.487057
NIA Mouse Gene Index U019434
EC 1.14.14.1
Consensus CDS Project CCDS29795.1
International Mouse Phenotyping Consortium Status Cyp2c39
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000028407 VEGA Gene Model | MGI Sequence Detail 57668 C57BL/6J ±  kb
transcript OTTMUST00000070386 VEGA | MGI Sequence Detail 1817 Not Applicable 
polypeptide OTTMUSP00000035863 VEGA | MGI Sequence Detail 490 Not Applicable 

For the selected sequences
All sequences(18) RefSeq(2) UniProt(2)
Polymorphisms
SNPs within 2kb(351 from dbSNP Build 137)    SNPs within 2kb including multiple locations(357)
Protein-related
information
ResourceIDDescription
InterPro IPR001128 Cytochrome P450
InterPro IPR017972 Cytochrome P450, conserved site
InterPro IPR002401 Cytochrome P450, E-class, group I
Protein Ontology PR:000006228 cytochrome P450 2C39
References
(Earliest) J:49570 Luo G, et al., Cloning and expression of murine CYP2Cs and their ability to metabolize arachidonic acid. Arch Biochem Biophys. 1998 Sep 1;357(1):45-57
(Latest) J:193325 Boj SF, et al., Diabetes risk gene and Wnt effector Tcf7l2/TCF4 controls hepatic response to perinatal and adult metabolic demand. Cell. 2012 Dec 21;151(7):1595-607
All references(28)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/20/2015
MGI 5.22
The Jackson Laboratory