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Ccl22
Gene Detail
 Symbol
Name
ID
Ccl22
chemokine (C-C motif) ligand 22
MGI:1306779
Synonyms ABCD-1, MDC, Scya22
Feature Type protein coding gene
Genetic Map
Chromosome 8
46.75 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr8:94745590-94751699 bp, + strand
From VEGA annotation of GRCm38

  6110 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:7529  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog

Protein SuperFamily: small inducible chemokine, C/CC types
Gene Tree: Ccl22

Human
homologs
Human Homolog CCL22, chemokine (C-C motif) ligand 22
NCBI Gene ID 6367
neXtProt AC  NX_O00626
Human Synonyms  ABCD-1, DC/B-CK, MDC, SCYA22, STCP-1
Human Chr (Location)  16q13; chr16:57358783-57366190 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Interactions
Ccl22 interacts with 213 markers (Mir7-2, Mir7b, Mir22, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (8 annotations)
Process chemotaxis, immune response, ...
Component extracellular region, extracellular space
Function chemokine activity, cytokine activity
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (11)    Tissues (5)   
Theiler Stages: 21, 23, 25, 28
Assay TypeResults
RT-PCR 11
cDNA source data(26)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(28) Genomic(1) cDNA(26) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000016635 (Evidence)
Ensembl Gene ModelENSMUSG00000031779 (Evidence)
Entrez Gene20299 (Evidence)
UniGene12895
DFCITC1578765
DoTSDT.489927
NIA Mouse Gene IndexU009672
Consensus CDS ProjectCCDS40441.1
International Mouse Knockout Project StatusCcl22
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016635 VEGA Gene Model | MGI Sequence Detail 6110 C57BL/6J ±  kb
transcript OTTMUST00000040245 VEGA | MGI Sequence Detail 2216 Not Applicable 
polypeptide OTTMUSP00000017971 VEGA | MGI Sequence Detail 92 Not Applicable 

For the selected sequences
All sequences(30) RefSeq(2) UniProt(3)
Polymorphisms SNPs within 2kb(24 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000827 CC chemokine, conserved site
InterPro IPR001811 Chemokine interleukin-8-like domain
Protein Ontology PR:000001994 C-C motif chemokine 22
References (Earliest) J:49499 Schaniel C, et al., Activated murine B lymphocytes and dendritic cells produce a novel CC chemokine which acts selectively on activated T cells. J Exp Med. 1998 Aug 3;188(3):451-63
(Latest) J:202893 Glowacki AJ, et al., Prevention of inflammation-mediated bone loss in murine and canine periodontal disease via recruitment of regulatory lymphocytes. Proc Natl Acad Sci U S A. 2013 Nov 12;110(46):18525-30
All references(42)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory