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Ccl22
Gene Detail
Symbol

Name
ID
Ccl22
chemokine (C-C motif) ligand 22
MGI:1306779
Synonyms
ABCD-1, MDC, Scya22
Feature Type
protein coding gene
Genetic Map
Chromosome 8
46.75 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr8:94745590-94751699 bp, + strand
From VEGA annotation of GRCm38

  6110 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:7529  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog

HCOP human homology predictions: CCL22
Protein SuperFamily: small inducible chemokine, C/CC types
Gene Tree: Ccl22

Human
homologs
CCL22, chemokine (C-C motif) ligand 22
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 6367
neXtProt AC: NX_O00626

Human Synonyms: A-152E5.1, ABCD-1, DC/B-CK, MDC, SCYA22, STCP-1

Human Chr (Location): 16q13; chr16:57358783-57366190 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Interactions
Ccl22 interacts with 212 markers (Mir7-2, Mir7b, Mir22, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (10 annotations)
Process cell chemotaxis, chemotaxis, ...
Component extracellular region, extracellular space
Function chemokine activity, cytokine activity
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (11)    Tissues (6)    Tissue x Stage Matrix (view)
Assay TypeResults
RT-PCR 11
cDNA source data(26)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(28) Genomic(1) cDNA(26) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000016635 (Evidence)
Ensembl Gene Model ENSMUSG00000031779 (Evidence)
Entrez Gene 20299 (Evidence)
UniGene 12895
DFCI TC1578765
DoTS DT.489927
NIA Mouse Gene Index U009672
Consensus CDS Project CCDS40441.1
International Mouse Phenotyping Consortium Status Ccl22
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016635 VEGA Gene Model | MGI Sequence Detail 6110 C57BL/6J ±  kb
transcript OTTMUST00000040245 VEGA | MGI Sequence Detail 2216 Not Applicable 
polypeptide OTTMUSP00000017971 VEGA | MGI Sequence Detail 92 Not Applicable 

For the selected sequences
All sequences(30) RefSeq(2) UniProt(3)
Polymorphisms
SNPs within 2kb(24 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000827 CC chemokine, conserved site
InterPro IPR030598 C-C motif chemokine 22
InterPro IPR001811 Chemokine interleukin-8-like domain
Protein Ontology PR:000001994 C-C motif chemokine 22
References
(Earliest) J:49499 Schaniel C, et al., Activated murine B lymphocytes and dendritic cells produce a novel CC chemokine which acts selectively on activated T cells. J Exp Med. 1998 Aug 3;188(3):451-63
(Latest) J:216439 Lee KM, et al., The chemokine receptors ACKR2 and CCR2 reciprocally regulate lymphatic vessel density. EMBO J. 2014 Nov 3;33(21):2564-80
All references(42)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory