Naip2
Gene Detail

Symbol Name ID

Naip2 NLR family, apoptosis inhibitory protein 2 MGI:1298226

Synonyms

Birc1b, Naip2, Naip-rs6

Feature Type

protein coding gene

Genetic Map

Chromosome 13

53.01 cM, cytoband D1-D3
Detailed Genetic Map ± 1 cM


Mapping data(10)

Sequence Map

Chr13:100144063-100202092 bp, - strand From VEGA annotation of GRCm38   58030 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

Protein SuperFamily: neuronal apoptosis inhibitory protein
Gene Tree: Naip2

Gene Ontology (GO) classifications

All GO classifications: (11 annotations)

Process	apoptotic process, cellular response to estrogen stimulus, ...
Component	IPAF inflammasome complex
Function	ATP binding, metal ion binding, ...

External Resources: FuncBase

Expression

Literature Summary: (3 records)
Data Summary: Results (47)    Tissues (43)    Images (3)
Theiler Stages: 17, 21, 22, 23, 28

Assay Type	Results
RNA in situ	37
RT-PCR	10

cDNA source data(11)
External Resources: GEO   ArrayExpress

Molecular reagents

All nucleic(29) Genomic(15) cDNA(11) Primer pair(3)
Microarray probesets(2)

Other database links

VEGA Gene Model	OTTMUSG00000028711 (Evidence)
Ensembl Gene Model	ENSMUSG00000078945 (Evidence)
Entrez Gene	17948 (Evidence)
UniGene	89961
DFCI	TC1585714
DoTS	DT.87051347, DT.99846715
NIA Mouse Gene Index	U303051
Consensus CDS Project	CCDS26726.1
International Mouse Knockout Project Status	Naip2

Sequences

Length	Strain/Species
genomic	OTTMUSG00000028711	VEGA Gene Model | MGI Sequence Detail	58030	C57BL/6J
transcript	OTTMUST00000071109	VEGA | MGI Sequence Detail	4823	Not Applicable
polypeptide	OTTMUSP00000036366	VEGA | MGI Sequence Detail	1447	Not Applicable

All sequences(52) RefSeq(4) UniProt(10)

Polymorphisms

PCR(2) : SNPs(257 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR003593	AAA+ ATPase domain
InterPro	IPR001370	Baculoviral inhibition of apoptosis protein repeat
InterPro	IPR007111	NACHT nucleoside triphosphatase
Protein Ontology	PR:000011553	baculoviral IAP repeat-containing protein 1b

References

(Earliest) J:37707 Scharf JM, et al., The mouse region syntenic for human spinal muscular atrophy lies within the Lgn1 critical interval and contains multiple copies of Naip exon 5. Genomics. 1996 Dec 15;38(3):405-17
(Latest) J:176197 Kofoed EM, et al., Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity. Nature. 2011 Sep 29;477(7366):592-5
All references(34)

Other accession IDs

MGD-MRK-38479, MGI:109434