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Cnih1 Gene Detail
Summary
  • Symbol
    Cnih1
  • Name
    cornichon family AMPA receptor auxiliary protein 1
  • Synonyms
    Cnih
  • Feature Type
    protein coding gene
  • IDs
    MGI:1277202
    NCBI Gene: 12793
  • Gene Overview
    MyGene.info: CNIH1
Location & Maps
more
  • Sequence Map
    Chr14:46775582-46788411 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      12830 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 24.29 cM, cytoband C1
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    CNIH1, cornichon family AMPA receptor auxiliary protein 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CNIH1, cornichon family AMPA receptor auxiliary protein 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CNIH, CNIH-1, CNIL, TGAM77
  • Links
    NCBI Gene ID: 10175
    neXtProt AC: NX_O95406

  • Chr Location
    14q22.2; chr14:54426929-54441430 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    11
  • Chemically induced (other)
    1
  • Gene trapped
    6
  • Targeted
    4
  • Genomic Mutations
    1 involving Cnih1
  • Incidental Mutations
The male homozygous mutant mice exhibited a decreased anxiety-like response during open field testing when compared with controls. The male mutants also exhibited decreased body weight, total tissue mass, and lean body mass.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023897 VEGA Gene Model | MGI Sequence Detail 12830 C57BL/6J ±  kb
transcript OTTMUST00000058382 VEGA | MGI Sequence Detail 1523 Not Applicable  
polypeptide OTTMUSP00000028280 VEGA | MGI Sequence Detail 144 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    138 from dbSNP Build 142
  • RFLP
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 12
    cDNA 12

    Microarray probesets 3
References
more
  • Summaries
    All 34
    Developmental Gene Expression 3
    Gene Ontology 2
    Phenotypes 10
  • Earliest
    J:53793 Hwang SY, et al., The mouse cornichon gene family. Dev Genes Evol. 1999 Feb;209(2):120-5
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory