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Cnih1
Gene Detail
Symbol

Name
ID
Cnih1
cornichon homolog 1 (Drosophila)
MGI:1277202
Synonyms
Cnih
Feature Type
protein coding gene
Genetic Map
Chromosome 14
24.29 cM, cytoband C1
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr14:46775582-46788411 bp, - strand
From VEGA annotation of GRCm38

  12830 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:4219  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: CNIH1
Protein SuperFamily: cornichon protein
Gene Tree: Cnih1

Human
homologs
CNIH1, cornichon family AMPA receptor auxiliary protein 1
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 10175
neXtProt AC: NX_O95406

Human Synonyms: CNIH, CNIH-1, CNIL, TGAM77

Human Chr (Location): 14q22.2; chr14:54426929-54441430 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(10) : Gene trapped(6) Targeted(4)
Incidental mutations (data from CvDC )
 
The male homozygous mutant mice exhibited a decreased anxiety-like response during open field testing when compared with controls. The male mutants also exhibited decreased body weight, total tissue mass, and lean body mass.
 
Interactions
Cnih1 interacts with 267 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process intracellular signal transduction, transport, ...
Component endoplasmic reticulum, Golgi apparatus, ...
Function molecular_function
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (93)    Tissues (93)    Images (23)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 93
cDNA source data(11)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase cnih1 ; ZFIN cnih1    NEW 
Molecular
reagents
All nucleic(12) cDNA(12)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000023897 (Evidence)
Ensembl Gene Model ENSMUSG00000015759 (Evidence)
Entrez Gene 12793 (Evidence)
DFCI TC1572563
DoTS DT.536537
NIA Mouse Gene Index U035459
Consensus CDS Project CCDS26980.1
International Mouse Phenotyping Consortium Status Cnih1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023897 VEGA Gene Model | MGI Sequence Detail 12830 C57BL/6J ±  kb
transcript OTTMUST00000058382 VEGA | MGI Sequence Detail 1523 Not Applicable 
polypeptide OTTMUSP00000028280 VEGA | MGI Sequence Detail 144 Not Applicable 

For the selected sequences
All sequences(37) RefSeq(8) UniProt(4)
Polymorphisms
RFLP(1) : SNPs within 2kb(139 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR003377 Cornichon
Protein Ontology PR:000005633 protein cornichon
References
(Earliest) J:53793 Hwang SY, et al., The mouse cornichon gene family. Dev Genes Evol. 1999 Feb;209(2):120-5
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(37)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory