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Igdcc3 Gene Detail
Summary
  • Symbol
    Igdcc3
  • Name
    immunoglobulin superfamily, DCC subclass, member 3
  • Synonyms
    2810401C09Rik, Punc, WI-14920
  • Feature Type
    protein coding gene
  • IDs
    MGI:1202390
    NCBI Gene: 19289
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:65141189-65185872 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 35.13 cM, cytoband D-E1
  • Mapping Data
    6 experiments
Strain
Comparison
more
  • SNPs within 2kb
    114 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1202390
protein coding gene Chr9:65141121-65187031 (+)
129S1/SvImJ MGP_129S1SvImJ_G0034950
protein coding gene Chr9:64845316-64893807 (+)
A/J MGP_AJ_G0034930
protein coding gene Chr9:62670244-62714667 (+)
AKR/J MGP_AKRJ_G0034860
protein coding gene Chr9:64139350-64186108 (+)
BALB/cJ MGP_BALBcJ_G0034923
protein coding gene Chr9:62391975-62438643 (+)
C3H/HeJ MGP_C3HHeJ_G0034633
protein coding gene Chr9:64663158-64708478 (+)
C57BL/6NJ MGP_C57BL6NJ_G0035442
protein coding gene Chr9:66623382-66671460 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032353
protein coding gene Chr9:62313902-62360588 (+)
CAST/EiJ MGP_CASTEiJ_G0033954
protein coding gene Chr9:64859413-64912267 (+)
CBA/J MGP_CBAJ_G0034604
protein coding gene Chr9:68934781-68986914 (+)
DBA/2J MGP_DBA2J_G0034763
protein coding gene Chr9:62445685-62491962 (+)
FVB/NJ MGP_FVBNJ_G0034705
protein coding gene Chr9:61763482-61808785 (+)
LP/J MGP_LPJ_G0034846
protein coding gene Chr9:65125536-65174839 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0034747
protein coding gene Chr9:70185843-70232857 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0035464
protein coding gene Chr9:64250903-64301375 (+)
PWK/PhJ MGP_PWKPhJ_G0033658
protein coding gene Chr9:62632540-62679978 (+)
SPRET/EiJ MGP_SPRETEiJ_G0033492
protein coding gene Chr9:64521805-64574324 (+)
WSB/EiJ MGP_WSBEiJ_G0034067
protein coding gene Chr9:64149512-64199348 (+)



Homology
more
  • Human Ortholog
    IGDCC3, immunoglobulin superfamily DCC subclass member 3
  • Vertebrate Orthologs
    10
  • Human Ortholog
    IGDCC3, immunoglobulin superfamily DCC subclass member 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    HsT18880, PUNC
  • Links
    NCBI Gene ID: 9543
    neXtProt AC: NX_Q8IVU1
    UniProt: Q8IVU1

  • Chr Location
    15q22.31; chr15:65327127-65378040 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 3590
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: IGDCC3
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 2 alleles in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    10
  • Chemically induced (other)
    1
  • Gene trapped
    5
  • Targeted
    4
  • Genomic Mutations
    1 involving Igdcc3
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
Homozygotes for a gene trap mutation exhibit reduced performance on the rotarod, suggesting impaired cerebellar function.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000032394 Ensembl Gene Model | MGI Sequence Detail 44684 C57BL/6J ±  kb
transcript ENSMUST00000217371 Ensembl | MGI Sequence Detail 3183 Not Applicable  
polypeptide ENSMUSP00000149084 Ensembl | MGI Sequence Detail 813 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 25
    Genomic 2
    cDNA 16
    Primer pair 5
    Other 2

    Microarray probesets 6
Other
Accession IDs
less
MGI:1330814, MGI:1917204, MGI:2143154
References
more
  • Summaries
    All 40
    Developmental Gene Expression 13
    Gene Ontology 2
    Phenotypes 8
  • Earliest
    J:46645 Salbaum JM, Punc, a novel mouse gene of the immunoglobulin superfamily, is expressed predominantly in the developing nervous system. Mech Dev. 1998 Feb;71(1-2):201-4
  • Latest
    J:229257 Gu Z, et al., Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion. PLoS One. 2015;10(3):e0121550

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory