Cbx7
Gene Detail

Symbol Name ID

Cbx7 chromobox 7 MGI:1196439

Synonyms

1600014J01Rik, D15Ertd417e

Feature Type

protein coding gene

Genetic Map

Chromosome 15

37.85 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr15:79915807-79971119 bp, - strand From VEGA annotation of GRCm38   55313 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:65296  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

Gene Tree: Cbx7

Human homologs

Human Homolog		CBX7, chromobox homolog 7
NCBI Gene ID		23492
neXtProt AC		NX_O95931
Human Chr (Location)		22q13.1; chr22:39526777-39548538 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(376) : Targeted(3) Gene trapped(373)

Gene Ontology (GO) classifications

All GO classifications: (15 annotations)

Process	chromatin modification, negative regulation of transcription from RNA polymerase II promoter, ...
Component	heterochromatin, nuclear chromatin, ...
Function	chromatin binding, methylated histone residue binding, ...

External Resources: FuncBase

Expression

Literature Summary: (2 records)
Data Summary: Results (15)    Tissues (15)    Images (10)
Theiler Stages: 21, 26, 28

Assay Type	Results
RNA in situ	15

cDNA source data(54)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(56) Genomic(1) cDNA(54) Primer pair(1)
Microarray probesets(5)

Other database links

VEGA Gene Model	OTTMUSG00000017275 (Evidence)
Ensembl Gene Model	ENSMUSG00000053411 (Evidence)
Entrez Gene	52609 (Evidence)
UniGene	323442
DFCI	TC1578246, TC1597407, TC1652023
NIA Mouse Gene Index	U036418
PDB	2KVM
Consensus CDS Project	CCDS37143.1
International Mouse Knockout Project Status	Cbx7

Sequences

Length	Strain/Species
genomic	OTTMUSG00000017275	VEGA Gene Model | MGI Sequence Detail	55313	C57BL/6J
transcript	OTTMUST00000041848	VEGA | MGI Sequence Detail	3388	Not Applicable
polypeptide	OTTMUSP00000018818	VEGA | MGI Sequence Detail	251	Not Applicable

All sequences(64) RefSeq(2) UniProt(6)

Polymorphisms

SNPs(120 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR023780	Chromo domain
InterPro	IPR023779	Chromo domain, conserved site
InterPro	IPR016197	Chromo domain-like
InterPro	IPR000953	Chromo domain/shadow
InterPro	IPR017984	Chromo domain subgroup
Protein Ontology	PR:000005088	chromobox protein 7

References

(Earliest) J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-le-grand). 1999 Jul;45(5):737-50
(Latest) J:184383 Forzati F, et al., CBX7 is a tumor suppressor in mice and humans. J Clin Invest. 2012 Feb 1;122(2):612-23
All references(46)

Other accession IDs

MGI:1917043, MGI:2146090