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Lilra6 Gene Detail
Summary
  • Symbol
    Lilra6
  • Name
    leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
  • Synonyms
    7M1, Pira3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1195969
    NCBI Gene: 18726
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr7:3911279-3918502 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 2.25 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    96 from dbSNP Build 142
  • Strain Annotations
    12
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1195969
protein coding gene Chr7:3911276-3918569 (-)
129S1/SvImJ MGP_129S1SvImJ_G0031532
protein coding gene Chr7:692010-698729 (-)
A/J MGP_AJ_G0031509
protein coding gene Chr7:758771-766612 (-)
AKR/J MGP_AKRJ_G0031435
protein coding gene Chr7:814538-847800 (-)
BALB/cJ MGP_BALBcJ_G0031514
protein coding gene Chr7:635594-656505 (-)
C3H/HeJ MGP_C3HHeJ_G0031236
protein coding gene Chr7:644317-652066 (-)
C57BL/6NJ MGP_C57BL6NJ_G0031975
protein coding gene Chr7:692352-765506 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029102
protein coding gene Chr7:593585-597561 (-)
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0031195
protein coding gene Chr7:811794-826227 (-)
DBA/2J no annotation
FVB/NJ MGP_FVBNJ_G0031306
protein coding gene Chr7:587158-760451 (-)
LP/J no annotation
NOD/ShiLtJ MGP_NODShiLtJ_G0031345
protein coding gene Chr7:880903-920696 (-)
NZO/HlLtJ no annotation
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0030154
protein coding gene Chr7:916233-930239 (-)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    LILRA1, leukocyte immunoglobulin like receptor A1
  • Vertebrate Orthologs
    9
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LILRA1, leukocyte immunoglobulin like receptor A1
  • Synonyms
    CD85I, LIR6, LIR-6
  • Links
    NCBI Gene ID: 11024
    neXtProt AC: NX_O75019
    UniProt: O75019

  • Chr Location
    19q13.42; chr19:54593576-54602381 (+)  GRCh38.p7

  • Human Ortholog
    LILRA2, leukocyte immunoglobulin like receptor A2
  • Synonyms
    CD85H, ILT1, LIR7, LIR-7
  • Links
    NCBI Gene ID: 11027
    neXtProt AC: NX_Q8N149
    UniProt: Q8N149

  • Chr Location
    19q13.42; chr19:54572997-54587560 (+)  GRCh38.p7

  • Human Ortholog
    LILRA3, leukocyte immunoglobulin like receptor A3
  • Synonyms
    CD85E, HM31, HM43, ILT6, ILT-6, LIR4, LIR-4
  • Links
    NCBI Gene ID: 11026
    neXtProt AC: NX_Q8N6C8
    UniProt: Q8N6C8

  • Chr Location
    19q13.4

  • Human Ortholog
    LILRA4, leukocyte immunoglobulin like receptor A4
  • Synonyms
    CD85g, ILT7
  • Links
    NCBI Gene ID: 23547
    neXtProt AC: NX_P59901
    UniProt: P59901

  • Chr Location
    19q13.42; chr19:54333185-54339169 (-)  GRCh38.p7

  • Human Ortholog
    LILRA6, leukocyte immunoglobulin like receptor A6
  • Synonyms
    CD85b, ILT5, ILT8, ILT-8, LILRB3, LILRB6
  • Links
    NCBI Gene ID: 79168
    UniProt: Q6PI73

  • Chr Location
    19q13.42; chr19:54236592-54242768 (-)  GRCh38.p7

  • Human Ortholog
    LILRB3, leukocyte immunoglobulin like receptor B3
  • Synonyms
    CD85A, HL9, ILT5, ILT-5, LILRA6, LIR3, LIR-3, PIRB, PIR-B
  • Links
    NCBI Gene ID: 11025
    neXtProt AC: NX_O75022
    UniProt: O75022

  • Chr Location
    19q13.42; chr19:54216278-54223087 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000030427 Ensembl Gene Model | MGI Sequence Detail 7224 C57BL/6J ±  kb
transcript ENSMUST00000038176 Ensembl | MGI Sequence Detail 2103 Not Applicable  
polypeptide ENSMUSP00000042636 Ensembl | MGI Sequence Detail 663 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 8
    cDNA 7
    Primer pair 1

    Microarray probesets 2
References
more
  • Summaries
    All 17
    Developmental Gene Expression 1
    Gene Ontology 2
  • Earliest
    J:44191 Kubagawa H, et al., A novel pair of immunoglobulin-like receptors expressed by B cells and myeloid cells [see comments]. Proc Natl Acad Sci U S A. 1997 May 13;94(10):5261-6
  • Latest
    J:237787 Liu X, et al., Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA. BMC Immunol. 2016 Aug 02;17(1):25

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
06/23/2022
MGI 6.20
The Jackson Laboratory