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Idh3g Gene Detail
Summary
  • Symbol
    Idh3g
  • Name
    isocitrate dehydrogenase 3 (NAD+), gamma
  • Feature Type
    protein coding gene
  • IDs
    MGI:1099463
    NCBI Gene: 15929
  • Gene Overview
    MyGene.info: IDH3G
  • Alliance
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:73778963-73786897 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome X, 37.41 cM, cytoband A7.3-B
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    70 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1099463
protein coding gene ChrX:73778963-73787008 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035820
protein coding gene ChrX:69554253-69562187 (-)
A/J MGP_AJ_G0035801
protein coding gene ChrX:69751224-69759158 (-)
AKR/J MGP_AKRJ_G0035726
protein coding gene ChrX:71571861-71579795 (-)
BALB/cJ MGP_BALBcJ_G0035786
protein coding gene ChrX:68782573-68790507 (-)
C3H/HeJ MGP_C3HHeJ_G0035491
protein coding gene ChrX:70027816-70035750 (-)
C57BL/6NJ MGP_C57BL6NJ_G0036316
protein coding gene ChrX:71684801-71692735 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0033160
protein coding gene ChrX:68781791-68789802 (-)
CAST/EiJ MGP_CASTEiJ_G0034782
protein coding gene ChrX:55373822-55381754 (-)
CBA/J MGP_CBAJ_G0035466
protein coding gene ChrX:73663751-73671685 (-)
DBA/2J MGP_DBA2J_G0035623
protein coding gene ChrX:69209365-69217299 (-)
FVB/NJ MGP_FVBNJ_G0035567
protein coding gene ChrX:68540430-68548368 (-)
LP/J MGP_LPJ_G0035708
protein coding gene ChrX:70336828-70344762 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035605
protein coding gene ChrX:76233337-76241271 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0036338
protein coding gene ChrX:69375602-69383540 (-)
PWK/PhJ MGP_PWKPhJ_G0034481
protein coding gene ChrX:53389687-53397607 (-)
SPRET/EiJ MGP_SPRETEiJ_G0034315
protein coding gene ChrX:56277061-56285020 (-)
WSB/EiJ MGP_WSBEiJ_G0034923
protein coding gene ChrX:68649462-68657412 (-)



Homology
more
  • Human Ortholog
    IDH3G, isocitrate dehydrogenase 3 (NAD(+)) gamma
  • Vertebrate Orthologs
    8
  • Human Ortholog
    IDH3G, isocitrate dehydrogenase 3 (NAD(+)) gamma
    Orthology source: HomoloGene, HGNC
  • Synonyms
    H-IDHG
  • Links
    NCBI Gene ID: 3421
    neXtProt AC: NX_P51553
    UniProt: P51553

  • Chr Location
    Xq28; chrX:153785766-153794523 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000002010 Ensembl Gene Model | MGI Sequence Detail 7935 C57BL/6J ±  kb
transcript ENSMUST00000052761 Ensembl | MGI Sequence Detail 1331 Not Applicable  
polypeptide ENSMUSP00000056502 Ensembl | MGI Sequence Detail 393 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    5 Sequences
  • Protein Ontology
    PR:000008891 isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial
  • InterPro Domains
    IPR004434 Isocitrate dehydrogenase NAD-dependent
    IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site
    IPR024084 Isopropylmalate dehydrogenase-like domain
Molecular
Reagents
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  • All nucleic 302
    Genomic 1
    cDNA 300
    Primer pair 1

    Microarray probesets 5
References
more
  • Summaries
    All 40
    Developmental Gene Expression 5
    Gene Ontology 6
    Phenotypes 7
  • Earliest
    J:42590 Brenner V, et al., Genomic organization of two novel genes on human Xq28: compact head to head arrangement of IDH gamma and TRAP delta is conserved in rat and mouse. Genomics. 1997 Aug 15;44(1):8-14
  • Latest
    J:240028 Bulusu V, et al., Spatiotemporal Analysis of a Glycolytic Activity Gradient Linked to Mouse Embryo Mesoderm Development. Dev Cell. 2017 Feb 27;40(4):331-341.e4

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory