About   Help   FAQ
Odf2
Gene Detail
Symbol

Name
ID
Odf2
outer dense fiber of sperm tails 2
MGI:1098824
Synonyms
cenexin, MMTEST29
Feature Type
protein coding gene
Genetic Map
Chromosome 2
20.79 cM, cytoband B
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr2:29889221-29931746 bp, + strand
From VEGA annotation of GRCm38

  42526 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:1907  Vertebrate Homology Class
1 human; 1 mouse; 1 chimpanzee; 1 rhesus macaque; 1 dog; 1 chicken; 1 zebrafish

HCOP human homology predictions: ODF2
Gene Tree: Odf2

Human
homologs
ODF2, outer dense fiber of sperm tails 2
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 4957
neXtProt AC: NX_Q5BJF6

Human Synonyms: CT134, ODF2/1, ODF2/2, ODF84

Human Chr (Location): 9q34.11; chr9:128455155-128501292 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(22) : Gene trapped(19) Targeted(3)
Incidental mutations (data from Mutagenetix , APF , CvDC )
 
Mice homozygous for a gene trapped allele exhibit embryonic lethality before implantation and transmission ratio distortion while all heterozygous males display normal development and fertility. Males heterozygous for other alleles are either infertile orshow reduced fertility.
 
Interactions
Odf2 interacts with 183 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (16 annotations)
Process cell differentiation, multicellular organismal development, ...
Component cell projection, centriole, ...
Function Rab GTPase binding, structural constituent of cytoskeleton
External Resources: FuncBase
Expression
Literature Summary: (6 records)
Data Summary: Results (44)    Tissues (25)    Images (25)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 20
In situ reporter (knock in) 6
Northern blot 2
RT-PCR 16
cDNA source data(12)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase odf2 ; ZFIN odf2b    NEW 
Molecular
reagents
All nucleic(17) cDNA(14) Primer pair(3)
Microarray probesets(8)
Other database
links
VEGA Gene Model OTTMUSG00000019165 (Evidence)
Ensembl Gene Model ENSMUSG00000026790 (Evidence)
Entrez Gene 18286 (Evidence)
DFCI TC1575827, TC1580270, TC1596655, TC1598635, TC1607260, TC1610282, TC1650695, TC1734752
DoTS DT.101393818, DT.101737758, DT.110660435, DT.110660441, DT.493099, DT.55245970, DT.91431109, DT.91593793, DT.99853324, DT.99853325
NIA Mouse Gene Index U042271, U050886, U050887
Consensus CDS Project CCDS15861.1, CCDS50554.1, CCDS50555.1, CCDS50556.1, CCDS50557.1
International Mouse Phenotyping Consortium Status Odf2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000019165 VEGA Gene Model | MGI Sequence Detail 42526 C57BL/6J ±  kb
transcript OTTMUST00000040452 VEGA | MGI Sequence Detail 3188 Not Applicable 
polypeptide OTTMUSP00000018076 VEGA | MGI Sequence Detail 830 Not Applicable 

For the selected sequences
All sequences(145) RefSeq(10) UniProt(10)
Polymorphisms
SNPs within 2kb(98 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR026099 Outer dense fibre protein 2-related
Protein Ontology PR:000011598 outer dense fiber protein 2
References
(Earliest) J:42726 Nakayama H, et al., Developmental restriction of Mash-2 expression in trophoblast correlates with potential activation of the notch-2 pathway. Dev Genet. 1997;21(1):21-30
(Latest) J:208267 Kobayashi T, et al., The CP110-interacting proteins Talpid3 and Cep290 play overlapping and distinct roles in cilia assembly. J Cell Biol. 2014 Jan 20;204(2):215-29
All references(50)
Other
accession IDs
MGI:2139073

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/25/2015
MGI 6.0
The Jackson Laboratory