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Odf2 Gene Detail
Summary
  • Symbol
    Odf2
  • Name
    outer dense fiber of sperm tails 2
  • Synonyms
    cenexin, MMTEST29
  • Feature Type
    protein coding gene
  • IDs
    MGI:1098824
    NCBI Gene: 18286
  • Gene Overview
    MyGene.info: ODF2
  • Alliance
  • Transcription Start Sites
    20 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:29889221-29931746 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 20.79 cM, cytoband B
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    98 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1098824
protein coding gene Chr2:29889014-29931746 (.)
129S1/SvImJ MGP_129S1SvImJ_G0025547
protein coding gene Chr2:28060068-28103929 (+)
A/J MGP_AJ_G0025525
protein coding gene Chr2:26961080-27005700 (+)
AKR/J MGP_AKRJ_G0025494
protein coding gene Chr2:27877491-27926720 (+)
BALB/cJ MGP_BALBcJ_G0025520
protein coding gene Chr2:27094268-27137202 (+)
C3H/HeJ MGP_C3HHeJ_G0025282
protein coding gene Chr2:27802981-27845219 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025965
protein coding gene Chr2:28973363-29016904 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0023374
protein coding gene Chr2:25751821-25795939 (+)
CAST/EiJ MGP_CASTEiJ_G0024745
protein coding gene Chr2:27694369-27737993 (+)
CBA/J MGP_CBAJ_G0025259
protein coding gene Chr2:29982921-30025129 (+)
DBA/2J MGP_DBA2J_G0025392
protein coding gene Chr2:26758376-26801744 (+)
FVB/NJ MGP_FVBNJ_G0025355
protein coding gene Chr2:26562017-26607025 (+)
LP/J MGP_LPJ_G0025478
protein coding gene Chr2:27984327-28030153 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0025385
protein coding gene Chr2:29902110-29947927 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0026024
protein coding gene Chr2:27797239-27842138 (+)
PWK/PhJ MGP_PWKPhJ_G0024491
protein coding gene Chr2:26587257-26629538 (+)
SPRET/EiJ MGP_SPRETEiJ_G0024291
protein coding gene Chr2:27872794-27915367 (+)
WSB/EiJ MGP_WSBEiJ_G0024813
protein coding gene Chr2:27914376-27958999 (+)



Homology
more
  • Human Ortholog
    ODF2, outer dense fiber of sperm tails 2
  • Vertebrate Orthologs
    7
  • Human Ortholog
    ODF2, outer dense fiber of sperm tails 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CT134, ODF2/1, ODF2/2, ODF84
  • Links
    NCBI Gene ID: 4957
    neXtProt AC: NX_Q5BJF6
    UniProt: Q5BJF6

  • Chr Location
    9q34.11; chr9:128455155-128501292 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    27 phenotypes from 4 alleles in 4 genetic backgrounds
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a gene trapped allele exhibit embryonic lethality before implantation and transmission ratio distortion while all heterozygous males display normal development and fertility. Males heterozygous for other alleles are either infertile orshow reduced fertility.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000026790 Ensembl Gene Model | MGI Sequence Detail 42526 C57BL/6J ±  kb
    transcript ENSMUST00000113765 Ensembl | MGI Sequence Detail 3188 Not Applicable  
    polypeptide ENSMUSP00000109394 Ensembl | MGI Sequence Detail 830 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 18
      cDNA 15
      Primer pair 3

      Microarray probesets 8
    Other
    Accession IDs
    less
    MGI:2139073
    References
    more
    • Summaries
      All 56
      Developmental Gene Expression 7
      Gene Ontology 13
      Phenotypes 13
    • Earliest
      J:42726 Nakayama H, et al., Developmental restriction of Mash-2 expression in trophoblast correlates with potential activation of the notch-2 pathway. Dev Genet. 1997;21(1):21-30
    • Latest
      J:240026 Minegishi K, et al., A Wnt5 Activity Asymmetry and Intercellular Signaling via PCP Proteins Polarize Node Cells for Left-Right Symmetry Breaking. Dev Cell. 2017 Mar 13;40(5):439-452.e4

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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    last database update
    11/13/2018
    MGI 6.13
    The Jackson Laboratory