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Odf2
Gene Detail
 Symbol
Name
ID
Odf2
outer dense fiber of sperm tails 2
MGI:1098824
Synonyms cenexin, MMTEST29
Feature Type protein coding gene
Genetic Map
Chromosome 2
20.79 cM, cytoband B
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr2:29889221-29931746 bp, + strand
From VEGA annotation of GRCm38

  42526 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:1907  Vertebrate Homology Class
1 human; 1 mouse; 1 chimpanzee; 1 rhesus macaque; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Odf2

Human
homologs
Human Homolog ODF2, outer dense fiber of sperm tails 2
NCBI Gene ID 4957
neXtProt AC  NX_Q5BJF6
Human Synonyms  CT134, ODF2/1, ODF2/2, ODF84
Human Chr (Location)  9q34.11; chr9:128455155-128501292 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(22) : Gene trapped(19) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a gene trapped allele exhibit embryonic lethality before implantation and transmission ratio distortion while all heterozygous males display normal development and fertility. Males heterozygous for other alleles are either infertile orshow reduced fertility.
 
Interactions
Odf2 interacts with 183 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (13 annotations)
Process cell differentiation, multicellular organismal development, ...
Component cell projection, centriole, ...
Function structural constituent of cytoskeleton
External Resources: FuncBase
Expression
Literature Summary: (6 records)
Data Summary: Results (41)    Tissues (21)    Images (19)
Theiler Stages: 5, 22, 24, 26, 28
Assay TypeResults
Immunohistochemistry 17
In situ reporter (knock in) 6
Northern blot 2
RT-PCR 16
cDNA source data(12)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(17) cDNA(14) Primer pair(3)
Microarray probesets(8)
Other database
links
VEGA Gene ModelOTTMUSG00000019165 (Evidence)
Ensembl Gene ModelENSMUSG00000026790 (Evidence)
Entrez Gene18286 (Evidence)
DFCITC1575827, TC1580270, TC1596655, TC1598635, TC1607260, TC1610282, TC1650695, TC1734752
DoTSDT.101393818, DT.101737758, DT.110660435, DT.110660441, DT.493099, DT.55245970, DT.91431109, DT.91593793, DT.99853324, DT.99853325
NIA Mouse Gene IndexU042271, U050886, U050887
Consensus CDS ProjectCCDS15861.1, CCDS50554.1, CCDS50555.1, CCDS50556.1, CCDS50557.1
International Mouse Knockout Project StatusOdf2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000019165 VEGA Gene Model | MGI Sequence Detail 42526 C57BL/6J ±  kb
transcript OTTMUST00000040452 VEGA | MGI Sequence Detail 3188 Not Applicable 
polypeptide OTTMUSP00000018076 VEGA | MGI Sequence Detail 830 Not Applicable 

For the selected sequences
All sequences(145) RefSeq(10) UniProt(10)
Polymorphisms SNPs within 2kb(98 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR026099 Outer dense fibre protein 2-related
Protein Ontology PR:000011598 outer dense fiber protein 2
References (Earliest) J:42726 Nakayama H, et al., Developmental restriction of Mash-2 expression in trophoblast correlates with potential activation of the notch-2 pathway. Dev Genet. 1997;21(1):21-30
(Latest) J:208267 Kobayashi T, et al., The CP110-interacting proteins Talpid3 and Cep290 play overlapping and distinct roles in cilia assembly. J Cell Biol. 2014 Jan 20;204(2):215-29
All references(52)
Other
accession IDs
MGI:2139073

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory