Kcns3
Gene Detail

Symbol Name ID

Kcns3 potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3 MGI:1098804

Synonyms

D12Ertd137e

Feature Type

protein coding gene

Genetic Map

Chromosome 12

5.58 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)

Sequence Map

Chr12:11090202-11150842 bp, - strand From NCBI annotation of GRCm38   60641 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:20518  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: potassium voltage-gated channel, alpha subunit, subfamilies A/C/D/F/G/S
Gene Tree: Kcns3

Human homologs

Human Homolog		KCNS3, potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3
NCBI Gene ID		3790
neXtProt AC		NX_Q9BQ31
Human Synonyms		KV9.3
Human Chr (Location)		2p24; chr2:18059945-18114225 (+)  GRCh37.p10

Alleles and phenotypes

All alleles(2) : Targeted(2)

Gene Ontology (GO) classifications

All GO classifications: (23 annotations)

Process	ion transport, potassium ion transmembrane transport, ...
Component	cytoplasm, Golgi apparatus, ...
Function	delayed rectifier potassium channel activity, ion channel activity, ...

External Resources: FuncBase

Expression

Literature Summary: (1 records)
Data Summary: Results (3)    Tissues (2)   
Theiler Stages: 25, 28

Assay Type	Results
RT-PCR	3

cDNA source data(14)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(17) Genomic(1) cDNA(14) Primer pair(2)
Microarray probesets(3)

Other database links

Ensembl Gene Model	ENSMUSG00000043673 (Evidence)
Entrez Gene	238076 (Evidence)
UniGene	113278
DFCI	TC1586025
DoTS	DT.101175653, DT.101343037, DT.99853812
NIA Mouse Gene Index	U033805
Consensus CDS Project	CCDS25813.1
International Mouse Knockout Project Status	Kcns3

Sequences

Length	Strain/Species
genomic	238076	NCBI Gene Model | MGI Sequence Detail	60641	C57BL/6J
transcript	NM_173417	RefSeq | MGI Sequence Detail	2933	C57BL/6
polypeptide	Q8BQZ8	UniProt | EBI | MGI Sequence Detail	491	Not Applicable

All sequences(27) RefSeq(4) UniProt(2)

Polymorphisms

SNPs(298 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR011333	BTB/POZ fold
InterPro	IPR000210	BTB/POZ-like
InterPro	IPR005821	Ion transport domain
InterPro	IPR003131	Potassium channel tetramerisation-type BTB domain
InterPro	IPR003968	Potassium channel, voltage dependent, Kv
InterPro	IPR003973	Potassium channel, voltage dependent, Kv2
InterPro	IPR003971	Potassium channel, voltage dependent, Kv9
InterPro	IPR003091	Voltage-dependent potassium channel
Protein Ontology	PR:000000800	voltage-gated potassium channel KCNS3

Graphical View of Protein Domain Structure

References

(Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(33)