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Kcns3
Gene Detail
 Symbol
Name
ID
Kcns3
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3
MGI:1098804
Synonyms D12Ertd137e
Feature Type protein coding gene
Genetic Map
Chromosome 12
5.58 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr12:11090202-11150842 bp, - strand
From NCBI annotation of GRCm38

  60641 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:20518  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: potassium voltage-gated channel, alpha subunit, subfamilies A/C/D/F/G/S
Gene Tree: Kcns3

Human
homologs
Human Homolog KCNS3, potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3
NCBI Gene ID 3790
neXtProt AC  NX_Q9BQ31
Human Synonyms  KV9.3
Human Chr (Location)  2p24; chr2:17877847-17932958 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Kcns3 interacts with 172 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (21 annotations)
Process ion transport, potassium ion transmembrane transport, ...
Component cytoplasm, Golgi apparatus, ...
Function delayed rectifier potassium channel activity, ion channel activity, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (3)    Tissues (3)   
Theiler Stages: 25, 27, 28
Assay TypeResults
RT-PCR 3
cDNA source data(14)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(17) Genomic(1) cDNA(14) Primer pair(2)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000043673 (Evidence)
Entrez Gene238076 (Evidence)
UniGene113278
DFCITC1586025
DoTSDT.101175653, DT.101343037, DT.99853812
NIA Mouse Gene IndexU033805
Consensus CDS ProjectCCDS25813.1
International Mouse Knockout Project StatusKcns3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 238076 NCBI Gene Model | MGI Sequence Detail 60641 C57BL/6J ±  kb
transcript NM_173417 RefSeq | MGI Sequence Detail 2933 C57BL/6 
polypeptide Q8BQZ8 UniProt | EBI | MGI Sequence Detail 491 Not Applicable 

For the selected sequences
All sequences(33) RefSeq(10) UniProt(2)
Polymorphisms SNPs within 2kb(380 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR011333 BTB/POZ fold
InterPro IPR000210 BTB/POZ-like
InterPro IPR005821 Ion transport domain
InterPro IPR003131 Potassium channel tetramerisation-type BTB domain
InterPro IPR003968 Potassium channel, voltage dependent, Kv
InterPro IPR003973 Potassium channel, voltage dependent, Kv2
InterPro IPR003971 Potassium channel, voltage dependent, Kv9
InterPro IPR003091 Voltage-dependent potassium channel
InterPro IPR027359 Voltage-dependent potassium channel, four helix bundle domain
Protein Ontology PR:000000800 voltage-gated potassium channel KCNS3
Graphical View of Protein Domain Structure
References (Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:205051 Miller JA, et al., Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates. Development. 2013 Nov;140(22):4633-44
All references(34)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory