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Kcns3
Gene Detail
Symbol

Name
ID
Kcns3
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3
MGI:1098804
Synonyms
D12Ertd137e
Feature Type
protein coding gene
Genetic Map
Chromosome 12
5.58 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr12:11090202-11150842 bp, - strand
From Ensembl annotation of GRCm38

  60641 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:20518  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: KCNS3
Protein SuperFamily: potassium voltage-gated channel, alpha subunit, subfamilies A/C/D/F/G/S
Gene Tree: Kcns3

Human
homologs
KCNS3, potassium voltage-gated channel, modifier subfamily S, member 3
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 3790
neXtProt AC: NX_Q9BQ31

Human Synonyms: KV9.3

Human Chr (Location): 2p24; chr2:17877847-17932961 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Kcns3 interacts with 172 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (21 annotations)
Process ion transport, potassium ion transmembrane transport, ...
Component cytoplasm, Golgi apparatus, ...
Function delayed rectifier potassium channel activity, ion channel activity, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (3)    Tissues (3)    Tissue x Stage Matrix (view)
Assay TypeResults
RT-PCR 3
cDNA source data(14)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(17) Genomic(1) cDNA(14) Primer pair(2)
Microarray probesets(3)
Other database
links
Ensembl Gene Model ENSMUSG00000043673 (Evidence)
Entrez Gene 238076 (Evidence)
UniGene 113278
DFCI TC1586025
DoTS DT.99853812, DT.101343037, DT.101175653
NIA Mouse Gene Index U033805
Consensus CDS Project CCDS25813.1
International Mouse Phenotyping Consortium Status Kcns3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000043673 Ensembl Gene Model | MGI Sequence Detail 60641 C57BL/6J ±  kb
transcript ENSMUST00000164495 Ensembl | MGI Sequence Detail 2870 Not Applicable 
polypeptide ENSMUSP00000129412 Ensembl | MGI Sequence Detail 491 Not Applicable 

For the selected sequences
All sequences(43) RefSeq(20) UniProt(2)
Polymorphisms
SNPs within 2kb(380 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR011333 BTB/POZ fold
InterPro IPR000210 BTB/POZ-like
InterPro IPR005821 Ion transport domain
InterPro IPR003131 Potassium channel tetramerisation-type BTB domain
InterPro IPR003968 Potassium channel, voltage dependent, Kv
InterPro IPR003973 Potassium channel, voltage dependent, Kv2
InterPro IPR003971 Potassium channel, voltage dependent, Kv9
InterPro IPR003091 Voltage-dependent potassium channel
InterPro IPR027359 Voltage-dependent potassium channel, four helix bundle domain
Protein Ontology PR:000000800 voltage-gated potassium channel KCNS3
References
(Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:205051 Miller JA, et al., Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates. Development. 2013 Nov;140(22):4633-44
All references(32)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory