Arvcf
Gene Detail

Symbol Name ID

Arvcf armadillo repeat gene deleted in velo-cardio-facial syndrome MGI:109620

Feature Type

protein coding gene

Genetic Map

Chromosome 16

11.37 cM
Detailed Genetic Map ± 1 cM


Mapping data(8)

Sequence Map

Chr16:18348182-18407076 bp, + strand From VEGA annotation of GRCm38   58895 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:31046  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Arvcf

Human homologs

Human Homolog		ARVCF, armadillo repeat gene deleted in velocardiofacial syndrome
NCBI Gene ID		421
neXtProt AC		NX_O00192
Human Chr (Location)		22q11.21; chr22:19957402-20004309 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(68) : Targeted(4) Gene trapped(64)

Gene Ontology (GO) classifications

All GO classifications: (7 annotations)

Process	calcium-dependent cell-cell adhesion, cell adhesion
Component	cytoplasm, nucleus, ...
Function	protein binding

External Resources: FuncBase

Expression

Literature Summary: (5 records)
Data Summary: Results (81)    Tissues (51)    Images (18)
Theiler Stages: 16, 17, 19, 20, 22, 23, 26, 28

Assay Type	Results
RNA in situ	49
RT-PCR	32

cDNA source data(87)
External Resources: Allen Institute   GENSAT   GEO   ArrayExpress

Molecular reagents

All nucleic(114) Genomic(24) cDNA(88) Primer pair(1) Other(1)
Microarray probesets(6)

Other database links

VEGA Gene Model	OTTMUSG00000026041 (Evidence)
Ensembl Gene Model	ENSMUSG00000000325 (Evidence)
Entrez Gene	11877 (Evidence)
UniGene	293599
DFCI	TC1574523, TC1590650, TC1594078, TC1602208, TC1628147, TC1674535
Consensus CDS Project	CCDS28020.1
International Mouse Knockout Project Status	Arvcf

Sequences

Length	Strain/Species
genomic	OTTMUSG00000026041	VEGA Gene Model | MGI Sequence Detail	58895	C57BL/6J
transcript	OTTMUST00000064282	VEGA | MGI Sequence Detail	4800	Not Applicable
polypeptide	OTTMUSP00000031897	VEGA | MGI Sequence Detail	962	Not Applicable

All sequences(79) RefSeq(12) UniProt(3)

Polymorphisms

RFLP(1) : SNPs(111 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR000225	Armadillo
InterPro	IPR011989	Armadillo-like helical
InterPro	IPR016024	Armadillo-type fold
Protein Ontology	PR:000004333	armadillo repeat protein deleted in velo-cardio-facial syndrome

References

(Earliest) J:39493 Sirotkin H, et al., Identification of a new human catenin gene family member (ARVCF) from the region deleted in velo-cardio-facial syndrome. Genomics. 1997 Apr 1;41(1):75-83
(Latest) J:191130 Maynard TM, et al., 22q11 Gene dosage establishes an adaptive range for sonic hedgehog and retinoic acid signaling during early development. Hum Mol Genet. 2013 Jan 15;22(2):300-12
All references(41)

Other accession IDs

MGD-MRK-39619