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Kifc1 Gene Detail
Summary
  • Symbol
    Kifc1
  • Name
    kinesin family member C1
  • Synonyms
    Gm4137, HSET, Kifc5a, kinesin family c-terminal 5A, KNSL2, Knsl2a, Tctex7, Tctex-7, Tctex7a, Tctex-7A
  • Feature Type
    protein coding gene
  • IDs
    MGI:109596
    NCBI Gene: 100502766
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:33875664-33890633 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 17.98 cM
  • Mapping Data
    7 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1 from dbSNP Build 142
  • Strain Annotations
    14
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_109596
protein coding gene Chr17:33875664-33890661 (-)
129S1/SvImJ MGP_129S1SvImJ_G0023409
protein coding gene Chr17:26141883-26162335 (+)
A/J MGP_AJ_G0023501
protein coding gene Chr17:32650327-32673051 (-)
AKR/J MGP_AKRJ_G0023467
protein coding gene Chr17:33036679-33048934 (-)
BALB/cJ MGP_BALBcJ_G0023504
protein coding gene Chr17:32801000-32805293 (-)
C3H/HeJ no annotation
C57BL/6NJ MGP_C57BL6NJ_G0023813
protein coding gene Chr17:27231536-27253569 (+)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0022633
protein coding gene Chr17:25785828-25792440 (+)
CBA/J MGP_CBAJ_G0023243
protein coding gene Chr17:36479999-36517086 (-)
DBA/2J no annotation
FVB/NJ MGP_FVBNJ_G0023207
protein coding gene Chr17:24695338-24702342 (+)
LP/J no annotation
NOD/ShiLtJ MGP_NODShiLtJ_G0023362
protein coding gene Chr17:35553491-35570476 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0023855
protein coding gene Chr17:25834151-25856348 (+)
PWK/PhJ MGP_PWKPhJ_G0022382
protein coding gene Chr17:23698215-23715257 (+)
SPRET/EiJ MGP_SPRETEiJ_G0022200
protein coding gene Chr17:23868931-23879693 (+)
WSB/EiJ MGP_WSBEiJ_G0022828
protein coding gene Chr17:33415229-33419264 (-)



Homology
more
  • Human Ortholog
    KIFC1, kinesin family member C1
  • Vertebrate Orthologs
    12
  • Human Ortholog
    KIFC1, kinesin family member C1
    Orthology source: HomoloGene
  • Synonyms
    HSET, KNSL2
  • Links
    NCBI Gene ID: 3833
    neXtProt AC: NX_Q9BW19
    UniProt: Q9BW19

  • Chr Location
    6p21.32; chr6:33391524-33410226 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 83229
    1 human;2 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;2 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: KIFC1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 100502766 NCBI Gene Model | MGI Sequence Detail 14970 C57BL/6J ±  kb
transcript NM_001195298 RefSeq | MGI Sequence Detail 2330 C57BL/6  
polypeptide Q9QWT9 UniProt | EBI | MGI Sequence Detail 674 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
Molecular
Reagents
less
  • All nucleic 37
    Genomic 1
    cDNA 33
    Primer pair 2
    Other 1

    Microarray probesets 1
Other
Accession IDs
less
MGD-MRK-14958, MGD-MRK-14959, MGD-MRK-14972, MGD-MRK-14973, MGD-MRK-39595, MGI:1346210, MGI:2137413, MGI:3782313, MGI:98651
References
more
  • Summaries
    All 35
    Developmental Gene Expression 6
    Gene Ontology 6
    Phenotypes 3
  • Earliest
    J:608 Ha H, et al., Several testis-expressed genes in the mouse t-complex have expression differences between wild-type and t-mutant mice. Dev Genet. 1991;12(4):318-32
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory