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Ccndbp1
Gene Detail
Symbol

Name
ID
Ccndbp1
cyclin D-type binding-protein 1
MGI:109595
Synonyms
DIP1, GCIP, Maid, SSEC-8, stage specific embryonic cDNA-8
Feature Type
protein coding gene
Genetic Map
Chromosome 2
60.37 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr2:121008403-121016904 bp, + strand
From VEGA annotation of GRCm38

  8502 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:7826  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Ccndbp1

Human
homologs
Human Homolog CCNDBP1, cyclin D-type binding-protein 1
NCBI Gene ID 23582
neXtProt AC  NX_O95273
Human Synonyms  DIP1, GCIP, HHM
Human Chr (Location)  15q14-q15; chr15:43185118-43197177 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Gene trapped(1) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a targeted null allele exhibit a delay in G1/S-phase progression of hepatocytes after partial hepatectomy and develop hepatocellular carcinomas at an advanced age.
 
Interactions
Ccndbp1 interacts with 61 markers (Mir7-2, Mir7b, Mir10a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (4 annotations)
Process cell cycle, regulation of cell cycle
Component cytoplasm, nucleus
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (62)    Tissues (52)    Images (4)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 1
Northern blot 12
RT-PCR 49
cDNA source data(116)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(118) cDNA(116) Primer pair(2)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000015966 (Evidence)
Ensembl Gene ModelENSMUSG00000023572 (Evidence)
Entrez Gene17151 (Evidence)
UniGene7838
DFCITC1572881, TC1596794, TC1739580
DoTSDT.103580000, DT.535747, DT.94260102, DT.94352331, DT.97340717
NIA Mouse Gene IndexU002342
Consensus CDS ProjectCCDS38213.1
International Mouse Knockout Project StatusCcndbp1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000015966 VEGA Gene Model | MGI Sequence Detail 8502 C57BL/6J ±  kb
transcript OTTMUST00000037983 VEGA | MGI Sequence Detail 1595 Not Applicable 
polypeptide OTTMUSP00000017039 VEGA | MGI Sequence Detail 375 Not Applicable 

For the selected sequences
All sequences(57) RefSeq(6) UniProt(1)
Polymorphisms
RFLP(1) : SNPs within 2kb(136 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR026907 Cyclin-D1-binding protein 1
Protein Ontology PR:000005124 cyclin-D1-binding protein 1
References
(Earliest) J:40782 Hwang SY, et al., Maid: a maternally transcribed novel gene encoding a potential negative regulator of bHLH proteins in the mouse egg and zygote. Dev Dyn. 1997 Jun;209(2):217-26
(Latest) J:184710 Ishii R, et al., Structure of a dominant-negative helix-loop-helix transcriptional regulator suggests mechanisms of autoinhibition. EMBO J. 2012;31(11):2541-52
All references(37)
Other
accession IDs
MGD-MRK-39594, MGI:2139199

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory