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Ifna11 Gene Detail
Summary
  • Symbol
    Ifna11
  • Name
    interferon alpha 11
  • Synonyms
    IFN-[a]11
  • Feature Type
    protein coding gene
  • IDs
    MGI:109210
    NCBI Gene: 15964
  • Member of
    Ifna cluster
  • Gene Overview
    MyGene.info: IFNA4
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr4:88819959-88820531 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 42.03 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    69 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_109210
protein coding gene Chr4:88819919-88820565 (+)
129S1/SvImJ MGP_129S1SvImJ_G0028435
protein coding gene Chr4:88692613-88693185 (+)
A/J MGP_AJ_G0028396
protein coding gene Chr4:85608568-85609260 (+)
AKR/J MGP_AKRJ_G0028344
protein coding gene Chr4:87733286-87733858 (+)
BALB/cJ MGP_BALBcJ_G0028415
protein coding gene Chr4:85828505-85829077 (+)
C3H/HeJ MGP_C3HHeJ_G0028128
protein coding gene Chr4:88445025-88445597 (+)
C57BL/6NJ MGP_C57BL6NJ_G0028854
protein coding gene Chr4:92108671-92109243 (+)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0027570
protein coding gene Chr4:86297082-86297656 (+)
CBA/J MGP_CBAJ_G0028098
protein coding gene Chr4:94954077-94957489 (+)
DBA/2J MGP_DBA2J_G0028249
protein coding gene Chr4:85375993-85376565 (+)
FVB/NJ MGP_FVBNJ_G0028214
protein coding gene Chr4:84314130-84314702 (+)
LP/J MGP_LPJ_G0028348
protein coding gene Chr4:89001949-89002521 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0028244
protein coding gene Chr4:99924988-99925560 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0028891
protein coding gene Chr4:87864756-87865328 (+)
PWK/PhJ MGP_PWKPhJ_G0027293
protein coding gene Chr4:83670773-83671340 (+)
SPRET/EiJ MGP_SPRETEiJ_G0027116
protein coding gene Chr4:85421667-85422242 (+)
WSB/EiJ MGP_WSBEiJ_G0027648
protein coding gene Chr4:88080030-88080602 (+)



Homology
more
  • Human Ortholog
    IFNA4, interferon alpha 4
  • Vertebrate Orthologs
    25
  • Human Ortholog
    IFNA4, interferon alpha 4
    Orthology source: HomoloGene
  • Synonyms
    IFN-alpha4a, INFA4
  • Links
    NCBI Gene ID: 3441
    neXtProt AC: NX_P05014
    UniProt: P05014

  • Chr Location
    9p21.3; chr9:21186618-21187599 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000100549 Ensembl Gene Model | MGI Sequence Detail 573 C57BL/6J ±  kb
transcript ENSMUST00000170428 Ensembl | MGI Sequence Detail 573 Not Applicable  
polypeptide ENSMUSP00000127921 Ensembl | MGI Sequence Detail 190 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 12
    Genomic 8
    cDNA 3
    Other 1

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-38254
References
more
  • Summaries
    All 28
    Gene Ontology 5
    Phenotypes 3
  • Earliest
    J:38311 Navarro S, et al., Isolation and characterization of a functional murine interferon alpha gene which is not expressed in fibroblasts upon virus induction. J Gen Virol. 1989 Jun;70(Pt 6):1381-9
  • Latest
    J:222144 Gibbert K, et al., Interferon-alpha subtype 11 activates NK cells and enables control of retroviral infection. PLoS Pathog. 2012;8(8):e1002868

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory