About 70% of homozygotes for a knock-out mutation die of heart failure shortly after birth due to massive cardiomyocyte apoptosis triggered by cardiovascular overload. Neonatal thymocytes and developing neuronal cells undergo apoptosis while cultured thymocytes are susceptible to apoptotic inducers.
|VEGA Gene Model||OTTMUSG00000018234 (Evidence)|
|Ensembl Gene Model||ENSMUSG00000026585 (Evidence)|
|Entrez Gene||16579 (Evidence)|
|DoTS||DT.533868, DT.101386480, DT.94156218|
|NIA Mouse Gene Index||U001010|
|Consensus CDS Project||CCDS35751.1|
|International Mouse Phenotyping Consortium Status||Kifap3|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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