Cct5
Gene Detail

Symbol Name ID

Cct5 chaperonin containing Tcp1, subunit 5 (epsilon) MGI:107185

Synonyms

Ccte, mKIAA0098, TCPE

Feature Type

protein coding gene

Genetic Map

Chromosome 15

13.02 cM, cytoband B3.2
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr15:31590800-31601847 bp, - strand From VEGA annotation of GRCm38   11048 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:6287  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Cct5

Human homologs

Human Homolog		CCT5, chaperonin containing TCP1, subunit 5 (epsilon)
NCBI Gene ID		22948
neXtProt AC		NX_P48643
Human Synonyms		CCTE, CCT-epsilon, TCP-1-epsilon
Human Chr (Location)		5p15.2; chr5:10250282-10266501 (+)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human CCT5

Alleles and phenotypes

All alleles(7) : Targeted(1) Gene trapped(6)

Gene Ontology (GO) classifications

All GO classifications: (16 annotations)

Process	binding of sperm to zona pellucida, cellular protein metabolic process, ...
Component	cell body, centrosome, ...
Function	ATP binding, nucleotide binding, ...

External Resources: FuncBase

Expression

Literature Summary: (1 records)
cDNA source data(461)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(461) cDNA(461)
Microarray probesets(4)

Other database links

VEGA Gene Model	OTTMUSG00000030800 (Evidence)
Ensembl Gene Model	ENSMUSG00000022234 (Evidence)
Entrez Gene	12465 (Evidence)
UniGene	282158
DFCI	TC1573898
DoTS	DT.101189908, DT.495587, DT.94411793, DT.97384515, DT.99867505
NIA Mouse Gene Index	U036065
Consensus CDS Project	CCDS27411.1
International Mouse Knockout Project Status	Cct5

Sequences

Length	Strain/Species
genomic	OTTMUSG00000030800	VEGA Gene Model | MGI Sequence Detail	11048	C57BL/6J
transcript	OTTMUST00000076216	VEGA | MGI Sequence Detail	1896	Not Applicable
polypeptide	OTTMUSP00000040095	VEGA | MGI Sequence Detail	541	Not Applicable

All sequences(52) RefSeq(2) UniProt(2)

Polymorphisms

SNPs(57 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR017998	Chaperone tailless complex polypeptide 1 (TCP-1)
InterPro	IPR002423	Chaperonin Cpn60/TCP-1
InterPro	IPR002194	Chaperonin TCP-1, conserved site
InterPro	IPR027409	GroEL-like apical domain
InterPro	IPR027413	GroEL-like equatorial domain
InterPro	IPR012718	T-complex protein 1, epsilon subunit
InterPro	IPR027410	TCP-1-like chaperonin intermediate domain
Protein Ontology	PR:000005153	T-complex protein 1 subunit epsilon

References

(Earliest) J:25228 Kubota H, et al., Identification of six Tcp-1-related genes encoding divergent subunits of the TCP-1-containing chaperonin. Curr Biol. 1994 Feb 1;4(2):89-99
(Latest) J:177736 Dun MD, et al., The Chaperonin Containing TCP1 Complex (CCT/TRiC) Is Involved in Mediating Sperm-Oocyte Interaction. J Biol Chem. 2011 Oct 21;286(42):36875-87
All references(43)

Other accession IDs

MGD-MRK-35646