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Cct5 Gene Detail
Summary
  • Symbol
    Cct5
  • Name
    chaperonin containing Tcp1, subunit 5 (epsilon)
  • Synonyms
    Ccte, mKIAA0098, TCPE
  • Feature Type
    protein coding gene
  • IDs
    MGI:107185
    NCBI Gene: 12465
  • Gene Overview
    MyGene.info: CCT5
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:31590813-31601804 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 13.02 cM, cytoband B3.2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    101 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_107185
protein coding gene Chr15:31590800-31601847 (-)
129S1/SvImJ MGP_129S1SvImJ_G0021768
protein coding gene Chr15:29848770-29859961 (-)
A/J MGP_AJ_G0021729
protein coding gene Chr15:28645405-28656451 (-)
AKR/J MGP_AKRJ_G0021706
protein coding gene Chr15:29376581-29389216 (-)
BALB/cJ MGP_BALBcJ_G0021735
protein coding gene Chr15:28652241-28663288 (-)
C3H/HeJ MGP_C3HHeJ_G0021510
protein coding gene Chr15:29399068-29410115 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022174
protein coding gene Chr15:31038547-31053189 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019712
protein coding gene Chr15:26738481-26749522 (-)
CAST/EiJ MGP_CASTEiJ_G0021026
protein coding gene Chr15:29892349-29903508 (-)
CBA/J MGP_CBAJ_G0021479
protein coding gene Chr15:31919739-31930786 (-)
DBA/2J MGP_DBA2J_G0021603
protein coding gene Chr15:28452477-28463524 (-)
FVB/NJ MGP_FVBNJ_G0021581
protein coding gene Chr15:27975248-27986295 (-)
LP/J MGP_LPJ_G0021672
protein coding gene Chr15:29718607-29731114 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021606
protein coding gene Chr15:34897727-34908754 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022197
protein coding gene Chr15:29631840-29642887 (-)
PWK/PhJ MGP_PWKPhJ_G0020770
protein coding gene Chr15:28614987-28626122 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020608
protein coding gene Chr15:29418325-29430684 (-)
WSB/EiJ MGP_WSBEiJ_G0021082
protein coding gene Chr15:29578399-29592728 (-)



Homology
more
  • Human Ortholog
    CCT5, chaperonin containing TCP1 subunit 5
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CCT5, chaperonin containing TCP1 subunit 5
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CCTE, CCT-epsilon, HEL-S-69, PNAS-102, TCP-1-epsilon
  • Links
    NCBI Gene ID: 22948
    neXtProt AC: NX_P48643
    UniProt: P48643

  • Chr Location
    5p15.2; chr5:10249921-10266412 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 6287
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: CCT5
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 12465 NCBI Gene Model | MGI Sequence Detail 10992 C57BL/6J ±  kb
transcript NM_007637 RefSeq | MGI Sequence Detail 1912 C57BL/6  
polypeptide P80316 UniProt | EBI | MGI Sequence Detail 541 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000005153 T-complex protein 1 subunit epsilon
  • InterPro Domains
    IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1)
    IPR002423 Chaperonin Cpn60/TCP-1 family
    IPR002194 Chaperonin TCP-1, conserved site
    IPR027409 GroEL-like apical domain superfamily
    IPR027413 GroEL-like equatorial domain superfamily
    IPR012718 T-complex protein 1, epsilon subunit
    IPR027410 TCP-1-like chaperonin intermediate domain superfamily
Molecular
Reagents
less
  • All nucleic 462
    cDNA 462

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-35646
References
more
  • Summaries
    All 50
    Developmental Gene Expression 2
    Gene Ontology 13
    Phenotypes 12
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:205312 Tarkar A, et al., DYX1C1 is required for axonemal dynein assembly and ciliary motility. Nat Genet. 2013 Sep;45(9):995-1003

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory