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Cct5
Gene Detail
Symbol

Name
ID
Cct5
chaperonin containing Tcp1, subunit 5 (epsilon)
MGI:107185
Synonyms
Ccte, mKIAA0098, TCPE
Feature Type
protein coding gene
Genetic Map
Chromosome 15
13.02 cM, cytoband B3.2
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr15:31590800-31601847 bp, - strand
From VEGA annotation of GRCm38

  11048 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:6287  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: CCT5
Gene Tree: Cct5

Human
homologs
CCT5, chaperonin containing TCP1, subunit 5 (epsilon)
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 22948
neXtProt AC: NX_P48643

Human Synonyms: CCTE, CCT-epsilon, HEL-S-69, PNAS-102, TCP-1-epsilon

Human Chr (Location): 5p15.2; chr5:10250170-10266389 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human CCT5

Mutations,
alleles, and
phenotypes
All mutations/alleles(7) : Gene trapped(6) Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Cct5 interacts with 34 markers (Mir18b, Mir103-2, Mir107, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (22 annotations)
Process binding of sperm to zona pellucida, protein folding, ...
Component cell body, centrosome, ...
Function ATP binding, beta-tubulin binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
cDNA source data(461)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase cct5 ; ZFIN cct5    NEW 
Molecular
reagents
All nucleic(461) cDNA(461)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000030800 (Evidence)
Ensembl Gene Model ENSMUSG00000022234 (Evidence)
Entrez Gene 12465 (Evidence)
UniGene 282158
DFCI TC1573898
DoTS DT.101189908, DT.495587, DT.94411793, DT.97384515, DT.99867505
NIA Mouse Gene Index U036065
Consensus CDS Project CCDS27411.1
International Mouse Phenotyping Consortium Status Cct5
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000030800 VEGA Gene Model | MGI Sequence Detail 11048 C57BL/6J ±  kb
transcript OTTMUST00000076216 VEGA | MGI Sequence Detail 1896 Not Applicable 
polypeptide OTTMUSP00000040095 VEGA | MGI Sequence Detail 541 Not Applicable 

For the selected sequences
All sequences(54) RefSeq(4) UniProt(2)
Polymorphisms
SNPs within 2kb(102 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1)
InterPro IPR002423 Chaperonin Cpn60/TCP-1 family
InterPro IPR002194 Chaperonin TCP-1, conserved site
InterPro IPR027409 GroEL-like apical domain
InterPro IPR027413 GroEL-like equatorial domain
InterPro IPR012718 T-complex protein 1, epsilon subunit
InterPro IPR027410 TCP-1-like chaperonin intermediate domain
Protein Ontology PR:000005153 T-complex protein 1 subunit epsilon
References
(Earliest) J:25228 Kubota H, et al., Identification of six Tcp-1-related genes encoding divergent subunits of the TCP-1-containing chaperonin. Curr Biol. 1994 Feb 1;4(2):89-99
(Latest) J:205312 Tarkar A, et al., DYX1C1 is required for axonemal dynein assembly and ciliary motility. Nat Genet. 2013 Sep;45(9):995-1003
All references(44)
Other
accession IDs
MGD-MRK-35646

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory