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Etfa Gene Detail
Summary
  • Symbol
    Etfa
  • Name
    electron transferring flavoprotein, alpha polypeptide
  • Synonyms
    2010200I21Rik, D9Ertd394e
  • Feature Type
    protein coding gene
  • IDs
    MGI:106092
    NCBI Gene: 110842
  • Gene Overview
    MyGene.info: ETFA
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:55454508-55512243 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 30.13 cM
  • Mapping Data
    10 experiments
Strain
Comparison
more
  • SNPs within 2kb
    182 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_106092
protein coding gene Chr9:55454436-55512243 (-)
129S1/SvImJ MGP_129S1SvImJ_G0034842
protein coding gene Chr9:54562680-54629158 (-)
A/J MGP_AJ_G0034823
protein coding gene Chr9:52795529-52855663 (-)
AKR/J MGP_AKRJ_G0034752
protein coding gene Chr9:54005203-54066729 (-)
BALB/cJ MGP_BALBcJ_G0034815
protein coding gene Chr9:52571265-52634830 (-)
C3H/HeJ MGP_C3HHeJ_G0034525
protein coding gene Chr9:54469708-54529384 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035334
protein coding gene Chr9:56068988-56130100 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032246
protein coding gene Chr9:52198004-52259399 (-)
CAST/EiJ MGP_CASTEiJ_G0033846
protein coding gene Chr9:54499410-54561507 (-)
CBA/J MGP_CBAJ_G0034496
protein coding gene Chr9:58022423-58088882 (-)
DBA/2J MGP_DBA2J_G0034655
protein coding gene Chr9:52687380-52745770 (-)
FVB/NJ MGP_FVBNJ_G0034597
protein coding gene Chr9:51891954-51950801 (-)
LP/J MGP_LPJ_G0034738
protein coding gene Chr9:54859118-54920596 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0034640
protein coding gene Chr9:59530351-59591055 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035356
protein coding gene Chr9:54022597-54080994 (-)
PWK/PhJ MGP_PWKPhJ_G0033551
protein coding gene Chr9:52681136-52740051 (-)
SPRET/EiJ MGP_SPRETEiJ_G0033386
protein coding gene Chr9:54295085-54358873 (-)
WSB/EiJ MGP_WSBEiJ_G0033959
protein coding gene Chr9:53983681-54043456 (-)



Homology
more
  • Human Ortholog
    ETFA, electron transfer flavoprotein subunit alpha
  • Vertebrate Orthologs
    10
  • Human Ortholog
    ETFA, electron transfer flavoprotein subunit alpha
    Orthology source: HomoloGene, HGNC
  • Synonyms
    EMA, GA2, MADD
  • Links
    NCBI Gene ID: 2108
    neXtProt AC: NX_P13804
    UniProt: P13804

  • Chr Location
    15q24.2-q24.3; chr15:76216228-76311469 (-)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with human ETFA associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000032314 Ensembl Gene Model | MGI Sequence Detail 57736 C57BL/6J ±  kb
transcript ENSMUST00000034866 Ensembl | MGI Sequence Detail 1392 Not Applicable  
polypeptide ENSMUSP00000034866 Ensembl | MGI Sequence Detail 333 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000007215 electron transfer flavoprotein subunit alpha, mitochondrial
  • InterPro Domains
    IPR029035 DHS-like NAD/FAD-binding domain superfamily
    IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal
    IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal
    IPR001308 Electron transfer flavoprotein alpha subunit/FixB
    IPR033947 Electron transfer flavoprotein, alpha subunit, N-terminal
    IPR018206 Electron transfer flavoprotein subunit alpha, conserved site
    IPR014729 Rossmann-like alpha/beta/alpha sandwich fold
Molecular
Reagents
less
  • All nucleic 14
    cDNA 13
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-33778, MGI:1196445, MGI:2444349
References
more
  • Summaries
    All 39
    Developmental Gene Expression 2
    Gene Ontology 8
    Phenotypes 2
  • Earliest
    J:32424 White RA, et al., Assignment of Etfdh, Etfb, and Etfa to chromosomes 3, 7, and 13: the mouse homologs of genes responsible for glutaric acidemia type II in human. Genomics. 1996 Apr 1;33(1):131-4
  • Latest
    J:184429 Yu Z, et al., Identification of neuroglobin-interacting proteins using yeast two-hybrid screening. Neuroscience. 2012 Jan 3;200:99-105

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory