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Etfa Gene Detail
Summary
  • Symbol
    Etfa
  • Name
    electron transferring flavoprotein, alpha polypeptide
  • Synonyms
    2010200I21Rik, D9Ertd394e
  • Feature Type
    protein coding gene
  • IDs
    MGI:106092
    NCBI Gene: 110842
  • Gene Overview
    MyGene.info: ETFA
Location & Maps
more
  • Sequence Map
    Chr9:55454508-55512243 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      57736 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    ETFA, electron transfer flavoprotein alpha subunit
  • Vertebrate Orthologs
    10
  • Human Ortholog
    ETFA, electron transfer flavoprotein alpha subunit
    Orthology source: HomoloGene
  • Synonyms
    EMA, GA2, MADD
  • Links
    NCBI Gene ID: 2108
    neXtProt AC: NX_P13804

  • Chr Location
    15q23-q25; chr15:76216287-76311469 (-)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human ETFA associations

Human Disease Mouse Models
       Multiple Acyl-CoA Dehydrogenase Deficiency; MADD   OMIM: 231680
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026421 VEGA Gene Model | MGI Sequence Detail 57736 C57BL/6J ±  kb
transcript OTTMUST00000065340 VEGA | MGI Sequence Detail 1392 Not Applicable  
polypeptide OTTMUSP00000032555 VEGA | MGI Sequence Detail 333 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    182 from dbSNP Build 142
  • RFLP
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000007215 electron transfer flavoprotein subunit alpha, mitochondrial
  • InterPro Domains
    IPR029035 DHS-like NAD/FAD-binding domain
    IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal
    IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal
    IPR001308 Electron transfer flavoprotein alpha subunit/FixB
    IPR018206 Electron transfer flavoprotein subunit alpha, conserved site
    IPR014729 Rossmann-like alpha/beta/alpha sandwich fold
Molecular
Reagents
less
  • All nucleic 13
    cDNA 12
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-33778, MGI:1196445, MGI:2444349
References
more
  • Summaries
    All 38
    Developmental Gene Expression 2
    Gene Ontology 7
    Phenotypes 2
  • Earliest
    J:32424 White RA, et al., Assignment of Etfdh, Etfb, and Etfa to chromosomes 3, 7, and 13: the mouse homologs of genes responsible for glutaric acidemia type II in human. Genomics. 1996 Apr 1;33(1):131-4
  • Latest
    J:184429 Yu Z, et al., Identification of neuroglobin-interacting proteins using yeast two-hybrid screening. Neuroscience. 2012 Jan 3;200:99-105

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/19/2016
MGI 6.03
The Jackson Laboratory