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Mageb3 Gene Detail
Summary
  • Symbol
    Mageb3
  • Name
    melanoma antigen, family B, 3
  • Synonyms
    Mage-b3, Mage-ps1, Mage-rs3, Smage3
  • Feature Type
    protein coding gene
  • IDs
    MGI:105109
    NCBI Gene: 17147
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr2:121953771-121956092 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 60.46 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    26 from dbSNP Build 142
  • Strain Annotations
    11
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_105109
protein coding gene Chr2:121953752-121956092 (-)
129S1/SvImJ no annotation
A/J MGP_AJ_G0026362
protein coding gene Chr2:119806950-119808289 (-)
AKR/J no annotation
BALB/cJ MGP_BALBcJ_G0026374
protein coding gene Chr2:120046805-120048227 (-)
C3H/HeJ MGP_C3HHeJ_G0026120
protein coding gene Chr2:123646397-123648992 (-)
C57BL/6NJ MGP_C57BL6NJ_G0026822
protein coding gene Chr2:128982792-128986331 (-)
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0026098
protein coding gene Chr2:133514587-133517185 (-)
DBA/2J MGP_DBA2J_G0026235
protein coding gene Chr2:119210493-119213463 (-)
FVB/NJ no annotation
LP/J MGP_LPJ_G0026337
protein coding gene Chr2:125169020-125171543 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0026217
protein coding gene Chr2:137733164-137736716 (-)
NZO/HlLtJ no annotation
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0025117
protein coding gene Chr2:122444374-122446101 (-)
WSB/EiJ MGP_WSBEiJ_G0025652
protein coding gene Chr2:124141082-124145263 (-)



Homology
more
  • Human Ortholog
    MAGEB1, MAGE family member B1
  • Vertebrate Orthologs
    7
  • Human Ortholog
    MAGEB1, MAGE family member B1
    Orthology source: HomoloGene
  • Synonyms
    CT3.1, DAM10, MAGEL1, MAGE-Xp
  • Links
    NCBI Gene ID: 4112
    neXtProt AC: NX_P43366
    UniProt: P43366

  • Chr Location
    Xp21.2; chrX:30243731-30252038 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    9
  • Chemically induced (other)
    1
  • Gene trapped
    5
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Mageb3
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 17147 NCBI Gene Model | MGI Sequence Detail 2322 C57BL/6J ±  kb
transcript NM_008545 RefSeq | MGI Sequence Detail 2322 C57BL/6  
polypeptide NP_032571 RefSeq | MGI Sequence Detail 330 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • InterPro Domains
    IPR002190 MAGE homology domain
    IPR041898 MAGE homology domain, winged helix WH1 motif
    IPR041899 MAGE homology domain, winged helix WH2 motif
    IPR037445 Melanoma-associated antigen
    IPR021072 Melanoma associated antigen, N-terminal
Molecular
Reagents
less
  • All nucleic 8
    Genomic 2
    cDNA 4
    Primer pair 2

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-32149
References
more
  • Summaries
    All 36
    Developmental Gene Expression 10
    Phenotypes 7
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:256265 Gordeeva OF, et al., Expression of Cancer-Testis Antigens of the Mage Family in Mouse Oocytes and Early Embryos. Russian Journal of Developmental Biology. 2017;48(4):287-294

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory