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Nin Gene Detail
Summary
  • Symbol
    Nin
  • Name
    ninein
  • Synonyms
    3110068G20Rik, mKIAA1565
  • Feature Type
    protein coding gene
  • IDs
    MGI:105108
    NCBI Gene: 18080
  • Gene Overview
    MyGene.info: NIN
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:70011435-70113717 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 12, 28.94 cM, cytoband C3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1325 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_105108
protein coding gene Chr12:70011435-70113830 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019806
protein coding gene Chr12:69737969-69841024 (-)
A/J MGP_AJ_G0019764
protein coding gene Chr12:67137906-67239078 (-)
AKR/J MGP_AKRJ_G0019740
protein coding gene Chr12:69148041-69250815 (-)
BALB/cJ MGP_BALBcJ_G0019744
protein coding gene Chr12:67603432-67704380 (-)
C3H/HeJ MGP_C3HHeJ_G0019550
protein coding gene Chr12:69620424-69725285 (-)
C57BL/6NJ MGP_C57BL6NJ_G0020196
protein coding gene Chr12:71965478-72066404 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017816
protein coding gene Chr12:64676517-64777305 (-)
CAST/EiJ MGP_CASTEiJ_G0019101
protein coding gene Chr12:64366666-64473937 (-)
CBA/J MGP_CBAJ_G0019519
protein coding gene Chr12:74636016-74751205 (-)
DBA/2J MGP_DBA2J_G0019635
protein coding gene Chr12:67052557-67153107 (-)
FVB/NJ MGP_FVBNJ_G0019622
protein coding gene Chr12:65950450-66053167 (-)
LP/J MGP_LPJ_G0019707
protein coding gene Chr12:69699064-69810130 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019661
protein coding gene Chr12:77932052-78037149 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0020231
protein coding gene Chr12:68632023-68732510 (-)
PWK/PhJ MGP_PWKPhJ_G0018866
protein coding gene Chr12:61318707-61421154 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018661
protein coding gene Chr12:63010632-63111934 (-)
WSB/EiJ MGP_WSBEiJ_G0019152
protein coding gene Chr12:69261444-69366429 (-)



Homology
more
  • Human Ortholog
    NIN, ninein
  • Vertebrate Orthologs
    10
  • Human Ortholog
    NIN, ninein
    Orthology source: HomoloGene, HGNC
  • Synonyms
    SCKL7
  • Links
    NCBI Gene ID: 51199
    neXtProt AC: NX_Q8N4C6
    UniProt: Q8N4C6

  • Chr Location
    14q22.1; chr14:50719763-50831121 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 40632
    1 human;1 mouse;2 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: NIN
  • Gene Tree
    Nin
Human Diseases
more
  • Diseases
    1 with human NIN associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000021068 Ensembl Gene Model | MGI Sequence Detail 102283 C57BL/6J ±  kb
    transcript ENSMUST00000222237 Ensembl | MGI Sequence Detail 9919 Not Applicable  
    polypeptide ENSMUSP00000152240 Ensembl | MGI Sequence Detail 2113 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 120
      cDNA 119
      Primer pair 1

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGD-MRK-32148, MGI:1920448, MGI:2144801, MGI:2144962
    References
    more
    • Summaries
      All 57
      Developmental Gene Expression 12
      Gene Ontology 20
      Phenotypes 6
    • Earliest
      J:31172 Bouckson-Castaing V, et al., Molecular characterisation of ninein, a new coiled-coil protein of the centrosome. J Cell Sci. 1996 Jan;109(Pt 1):179-90
    • Latest
      J:236302 Zhang X, et al., Cell-Type-Specific Alternative Splicing Governs Cell Fate in the Developing Cerebral Cortex. Cell. 2016 Aug 25;166(5):1147-1162.e15

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
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    last database update
    11/06/2018
    MGI 6.13
    The Jackson Laboratory