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Nin
Gene Detail
Symbol

Name
ID
Nin
ninein
MGI:105108
Synonyms
3110068G20Rik, mKIAA1565
Feature Type
protein coding gene
Genetic Map
Chromosome 12
28.94 cM, cytoband C3
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr12:70011435-70102854 bp, - strand
From VEGA annotation of GRCm38

  91420 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:40632  Vertebrate Homology Class
1 human; 1 mouse; 2 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog

HCOP human homology predictions: NIN
Gene Tree: Nin

Human
homologs
NIN, ninein (GSK3B interacting protein)
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 51199
neXtProt AC: NX_Q8N4C6

Human Synonyms: SCKL7

Human Chr (Location): 14q22.1; chr14:50719763-50831165 (-)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human NIN

Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Nin interacts with 415 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (15 annotations)
Process centrosome-templated microtubule nucleation, microtubule anchoring at centrosome
Component centriole, centrosome, ...
Function calcium ion binding, GTP binding, ...
External Resources: FuncBase
Expression
Literature Summary: (9 records)
Data Summary: Results (53)    Tissues (8)    Images (26)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 52
RT-PCR 1
cDNA source data(118)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase nin    NEW 
Molecular
reagents
All nucleic(119) cDNA(118) Primer pair(1)
Microarray probesets(5)
Other database
links
VEGA Gene Model OTTMUSG00000037170 (Evidence)
Ensembl Gene Model ENSMUSG00000021068 (Evidence)
Entrez Gene 18080 (Evidence)
UniGene 244047
DFCI TC1581229, TC1605367, TC1617416, TC1619898, TC1652877, TC1674241
DoTS DT.101377489, DT.101377490, DT.102556339, DT.110941684, DT.40138364, DT.91332183, DT.91358763, DT.91420711, DT.94174722, DT.94369562, DT.97411588, DT.99569957
NIA Mouse Gene Index U034043
Consensus CDS Project CCDS36468.1, CCDS36469.1
International Mouse Phenotyping Consortium Status Nin
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000037170 VEGA Gene Model | MGI Sequence Detail 91420 C57BL/6J ±  kb
transcript OTTMUST00000095750 VEGA | MGI Sequence Detail 9654 Not Applicable 
polypeptide OTTMUSP00000053440 VEGA | MGI Sequence Detail 2113 Not Applicable 

For the selected sequences
All sequences(91) RefSeq(24) UniProt(7)
Polymorphisms
SNPs within 2kb(1317 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002048 EF-hand domain
InterPro IPR011992 EF-hand-like domain
Protein Ontology PR:000011212 ninein
References
(Earliest) J:31172 Bouckson-Castaing V, et al., Molecular characterisation of ninein, a new coiled-coil protein of the centrosome. J Cell Sci. 1996 Jan;109(Pt 1):179-90
(Latest) J:219928 Srivatsa S, et al., Sip1 Downstream Effector ninein Controls Neocortical Axonal Growth, Ipsilateral Branching, and Microtubule Growth and Stability. Neuron. 2015 Mar 4;85(5):998-1012
All references(47)
Other
accession IDs
MGD-MRK-32148, MGI:1920448, MGI:2144801, MGI:2144962

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/18/2015
MGI 6.0
The Jackson Laboratory