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Nin
Gene Detail
Symbol

Name
ID
Nin
ninein
MGI:105108
Synonyms
3110068G20Rik, mKIAA1565
Feature Type
protein coding gene
Genetic Map
Chromosome 12
28.94 cM, cytoband C3
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr12:70011435-70102854 bp, - strand
From VEGA annotation of GRCm38

  91420 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:40632  Vertebrate Homology Class
1 human; 1 mouse; 2 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog

Gene Tree: Nin

Human
homologs
Human Homolog NIN, ninein (GSK3B interacting protein)
NCBI Gene ID 51199
neXtProt AC  NX_Q8N4C6
Human Synonyms  SCKL7
Human Chr (Location)  14q22.1; chr14:50719763-50831121 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human NIN
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Nin interacts with 416 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (16 annotations)
Process centrosome-templated microtubule nucleation, microtubule anchoring at centrosome
Component cell, centriole, ...
Function calcium ion binding, GTP binding, ...
External Resources: FuncBase
Expression
Literature Summary: (8 records)
Data Summary: Results (53)    Tissues (8)    Images (26)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 52
RT-PCR 1
cDNA source data(118)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(119) cDNA(118) Primer pair(1)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000037170 (Evidence)
Ensembl Gene ModelENSMUSG00000021068 (Evidence)
Entrez Gene18080 (Evidence)
UniGene244047
DFCITC1581229, TC1605367, TC1617416, TC1619898, TC1652877, TC1674241
DoTSDT.101377489, DT.101377490, DT.102556339, DT.110941684, DT.40138364, DT.91332183, DT.91358763, DT.91420711, DT.94174722, DT.94369562, DT.97411588, DT.99569957
NIA Mouse Gene IndexU034043
Consensus CDS ProjectCCDS36468.1, CCDS36469.1
International Mouse Knockout Project StatusNin
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000037170 VEGA Gene Model | MGI Sequence Detail 91420 C57BL/6J ±  kb
transcript OTTMUST00000095750 VEGA | MGI Sequence Detail 9654 Not Applicable 
polypeptide OTTMUSP00000053440 VEGA | MGI Sequence Detail 2113 Not Applicable 

For the selected sequences
All sequences(96) RefSeq(23) UniProt(13)
Polymorphisms
SNPs within 2kb(1317 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002048 EF-hand domain
InterPro IPR011992 EF-hand-like domain
Protein Ontology PR:000011212 ninein
References
(Earliest) J:31172 Bouckson-Castaing V, et al., Molecular characterisation of ninein, a new coiled-coil protein of the centrosome. J Cell Sci. 1996 Jan;109(Pt 1):179-90
(Latest) J:206657 Ye X, et al., C2cd3 is critical for centriolar distal appendage assembly and ciliary vesicle docking in mammals. Proc Natl Acad Sci U S A. 2014 Feb 11;111(6):2164-9
All references(46)
Other
accession IDs
MGD-MRK-32148, MGI:1920448, MGI:2144801, MGI:2144962

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
10/21/2014
MGI 5.20
The Jackson Laboratory