About   Help   FAQ
Tes
Gene Detail
Symbol

Name
ID
Tes
testis derived transcript
MGI:105081
Synonyms
D6Ertd352e, Tes1, Tes2, testin, testin2
Feature Type
protein coding gene
Genetic Map
Chromosome 6
7.67 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr6:17065149-17105828 bp, + strand
From VEGA annotation of GRCm38

  40680 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:41051  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: TES
Gene Tree: Tes

Human
homologs
TES, testin LIM domain protein
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 26136
neXtProt AC: NX_Q9UGI8

Human Synonyms: TESS, TESS-2

Human Chr (Location): 7q31.2; chr7:116210493-116258786 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(2) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous and heterozygous null mice display small forestomachs with thickened epithelium and increased tumor incidence and malignancy.
 
Phenotype Images(2)
Interactions
Tes interacts with 209 markers (Mir1b, Mir9-1, Mir9-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process negative regulation of cell proliferation, regulation of cell proliferation
Component cell junction, cytoplasm, ...
Function metal ion binding, poly(A) RNA binding, ...
External Resources: FuncBase
Expression
Literature Summary: (9 records)
Data Summary: Results (399)    Tissues (180)    Images (56)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 256
In situ reporter (knock in) 80
Western blot 3
RT-PCR 60
cDNA source data(14)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: GEISHA TES ; Xenbase tes    NEW 
Molecular
reagents
All nucleic(20) cDNA(14) Primer pair(6)
Microarray probesets(5)
Other database
links
VEGA Gene Model OTTMUSG00000022490 (Evidence)
Ensembl Gene Model ENSMUSG00000029552 (Evidence)
Entrez Gene 21753 (Evidence)
DFCI TC1576076, TC1579977, TC1649363
DoTS DT.101212290, DT.101381445, DT.101381446, DT.533304, DT.91597795
NIA Mouse Gene Index U057059
Consensus CDS Project CCDS19921.1, CCDS39429.1
International Mouse Phenotyping Consortium Status Tes
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022490 VEGA Gene Model | MGI Sequence Detail 40680 C57BL/6J ±  kb
transcript OTTMUST00000053834 VEGA | MGI Sequence Detail 2440 Not Applicable 
polypeptide OTTMUSP00000025619 VEGA | MGI Sequence Detail 419 Not Applicable 

For the selected sequences
All sequences(48) RefSeq(3) UniProt(5)
Polymorphisms
SNPs within 2kb(474 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR010442 PET domain
InterPro IPR027683 Testin
InterPro IPR001781 Zinc finger, LIM-type
Protein Ontology PR:000016239 testin
References
(Earliest) J:25123 Divecha N, et al., Cloning and characterisation of two new cDNAs encoding murine triple LIM domains. Gene. 1995 Apr 24;156(2):283-6
(Latest) J:202995 Ren DD, et al., Testin interacts with vangl2 genetically to regulate inner ear sensory cell orientation and the normal development of the female reproductive tract in mice. Dev Dyn. 2013 Dec;242(12):1454-65
All references(44)
Other
accession IDs
MGD-MRK-32121, MGI:1196300

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/25/2015
MGI 6.0
The Jackson Laboratory