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Tes Gene Detail
Summary
  • Symbol
    Tes
  • Name
    testis derived transcript
  • Synonyms
    D6Ertd352e, Tes1, Tes2, testin, testin2
  • Feature Type
    protein coding gene
  • IDs
    MGI:105081
    NCBI Gene: 21753
  • Gene Overview
    MyGene.info: TES
Location & Maps
more
  • Sequence Map
    Chr6:17065149-17105828 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      40680 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 7.67 cM
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    TES, testin LIM domain protein
  • Vertebrate Orthologs
    10
  • Human Ortholog
    TES, testin LIM domain protein
    Orthology source: HomoloGene, HGNC
  • Synonyms
    TESS, TESS-2
  • Links
    NCBI Gene ID: 26136
    neXtProt AC: NX_Q9UGI8

  • Chr Location
    7q31.2; chr7:116210493-116258786 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 41051
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed
  • HCOP
    human homology predictions: TES
  • Gene Tree
    Tes
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    5 phenotypes from 2 alleles in 2 genetic backgrounds
    2 images
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    5
  • Gene trapped
    2
  • Targeted
    3
  • Incidental Mutations
Homozygous and heterozygous null mice display small forestomachs with thickened epithelium and increased tumor incidence and malignancy.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022490 VEGA Gene Model | MGI Sequence Detail 40680 C57BL/6J ±  kb
transcript OTTMUST00000053834 VEGA | MGI Sequence Detail 2440 Not Applicable  
polypeptide OTTMUSP00000025619 VEGA | MGI Sequence Detail 419 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    473 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 20
    cDNA 14
    Primer pair 6

    Microarray probesets 5
Other
Accession IDs
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MGD-MRK-32121, MGI:1196300
References
more
  • Summaries
    All 41
    Developmental Gene Expression 9
    Gene Ontology 4
    Phenotypes 8
  • Earliest
    J:25123 Divecha N, et al., Cloning and characterisation of two new cDNAs encoding murine triple LIM domains. Gene. 1995 Apr 24;156(2):283-6
  • Latest
    J:202995 Ren DD, et al., Testin interacts with vangl2 genetically to regulate inner ear sensory cell orientation and the normal development of the female reproductive tract in mice. Dev Dyn. 2013 Dec;242(12):1454-65

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory