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Rab10
Gene Detail
Symbol

Name
ID
Rab10
RAB10, member RAS oncogene family
MGI:105066
Feature Type
protein coding gene
Genetic Map
Chromosome 12
1.71 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr12:3247430-3309969 bp, - strand
From Ensembl annotation of GRCm38

  62540 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:41111  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

HCOP human homology predictions: RAB10
Protein SuperFamily: Ras-related protein Rab
Gene Tree: Rab10

Human
homologs
RAB10, RAB10, member RAS oncogene family
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 10890
neXtProt AC: NX_P61026

Human Chr (Location): 2p23.3; chr2:26033860-26137454 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(23) : Gene trapped(21) Targeted(2)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Rab10 interacts with 365 markers (Mir7-1, Mir10b, Mir15a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (51 annotations)
Process antigen processing and presentation, axonogenesis, ...
Component cell, cell projection, ...
Function GDP binding, GTPase activity, ...
External Resources: FuncBase
Expression
cDNA source data(24)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase rab10 ; ZFIN rab10    NEW 
Molecular
reagents
All nucleic(27) cDNA(27)
Microarray probesets(6)
Other database
links
Ensembl Gene Model ENSMUSG00000020671 (Evidence)
Entrez Gene 19325 (Evidence)
DFCI TC1573388, TC1605208
DoTS DT.101405537, DT.87072967
NIA Mouse Gene Index U033752
Consensus CDS Project CCDS25782.1
International Mouse Phenotyping Consortium Status Rab10
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000020671 Ensembl Gene Model | MGI Sequence Detail 62540 C57BL/6J ±  kb
transcript ENSMUST00000021001 Ensembl | MGI Sequence Detail 3511 Not Applicable 
polypeptide ENSMUSP00000021001 Ensembl | MGI Sequence Detail 200 Not Applicable 

For the selected sequences
All sequences(57) RefSeq(2) UniProt(3)
Polymorphisms
RFLP(1) : SNPs within 2kb(199 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR001806 Small GTPase superfamily
InterPro IPR003579 Small GTPase superfamily, Rab type
InterPro IPR005225 Small GTP-binding protein domain
Protein Ontology PR:000013578 ras-related protein Rab-10
References
(Earliest) J:30578 Barbosa MD, et al., The Rab protein family: genetic mapping of six Rab genes in the mouse. Genomics. 1995 Dec 10;30(3):439-44
(Latest) J:211898 Sato T, et al., Rab8a and Rab8b are essential for several apical transport pathways but insufficient for ciliogenesis. J Cell Sci. 2014 Jan 15;127(Pt 2):422-31
All references(42)
Other
accession IDs
MGD-MRK-32105, MGI:2145003

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory