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T(7;18)50H Cytogenetic Marker Detail
Summary
  • Symbol
    T(7;18)50H
  • Name
    reciprocal translocation, Chr 7 and 18, Harwell 50
  • Synonyms
    T50H
  • Feature Type
    reciprocal chromosomal translocation
  • IDs
    MGI:103975
    NCBI Gene: 21266
Location & Maps
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  • Sequence Map
    Genome coordinates not available
  • Genetic Map
    Chromosome 7, cytoband E2
Human Diseases
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  • Diseases
    1 with T(7;18)50H mouse models

Human Disease Mouse Models
      
IDs
View 1 model
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    25 phenotypes from 1 allele in 3 genetic backgrounds
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice heterozygous for this reciprocal translocation have reduced fertility. Unbalanced forms of this translocation comprising maternal or paternal duplication of Chr7 segments are used to study associated imprinted phenotypes.
Sequences &
Gene Models
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Other
Accession IDs
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MGD-MRK-25297
References
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  • Summaries
    All 13
    Diseases 1
    Phenotypes 9
  • Earliest
    J:12947 Lyon MF, et al., The overall rates of dominant and recessive lethal and visible mutation induced by spermatogonial X-irradiation of mice. Genet Res. 1964;5:448-467
  • Latest
    J:198496 Resnick JL, et al., Recommendations for the investigation of animal models of Prader-Willi syndrome. Mamm Genome. 2013 Jun;24(5-6):165-78

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/08/2017
MGI 6.10
The Jackson Laboratory