About   Help   FAQ
Sult1a1 Gene Detail
Summary
  • Symbol
    Sult1a1
  • Name
    sulfotransferase family 1A, phenol-preferring, member 1
  • Synonyms
    PST, Stp1
  • Feature Type
    protein coding gene
  • IDs
    MGI:102896
    NCBI Gene: 20887
  • Gene Overview
    MyGene.info: SULT1A1
Location & Maps
more
  • Sequence Map
    Chr7:126672865-126676432 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      3568 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 69.25 cM
  • Mapping Data
    16 experiments
Homology
more
  • Human Ortholog
    SULT1A1, sulfotransferase family 1A member 1
  • Vertebrate Orthologs
    6
  • Human Ortholog
    SULT1A1, sulfotransferase family 1A member 1
    Orthology source: HGNC
  • Synonyms
    HAST1/HAST2, P-PST, PST, ST1A1, ST1A3, STP, STP1, TSPST1
  • Links
    NCBI Gene ID: 6817
    neXtProt AC: NX_P50225

  • Chr Location
    16p12.1; chr16:28605587-28623586 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    3 phenotypes from multigenic genotypes
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    4
  • Targeted
    3
  • Transgenic
    1
  • Incidental Mutations
    APF
Mice homozygous for a knock-out allele exhibit decrease hepatic DNA adduct formation induced by methyleugenol.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000025254 VEGA Gene Model | MGI Sequence Detail 3568 C57BL/6J ±  kb
transcript OTTMUST00000062172 VEGA | MGI Sequence Detail 1289 Not Applicable  
polypeptide OTTMUSP00000030607 VEGA | MGI Sequence Detail 291 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    42 from dbSNP Build 142
  • RFLP
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 55
    cDNA 55

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-14633, MGD-MRK-23730, MGI:2141894
References
more
  • Summaries
    All 51
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 7
  • Earliest
    J:2300 Charles CH, et al., cDNA sequence of a growth factor-inducible immediate early gene and characterization of its encoded protein. Oncogene. 1992 Jan;7(1):187-90
  • Latest
    J:217578 Bendadani C, et al., Determination of sulfotransferase forms involved in the metabolic activation of the genotoxicant 1-hydroxymethylpyrene using bacterially expressed enzymes and genetically modified mouse models. Chem Res Toxicol. 2014 Jun 16;27(6):1060-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
09/27/2016
MGI 6.05
The Jackson Laboratory