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Sult1a1 Gene Detail
Summary
  • Symbol
    Sult1a1
  • Name
    sulfotransferase family 1A, phenol-preferring, member 1
  • Synonyms
    PST, Stp1
  • Feature Type
    protein coding gene
  • IDs
    MGI:102896
    NCBI Gene: 20887
  • Gene Overview
    MyGene.info: SULT1A1
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:126672865-126676432 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 69.25 cM
  • Mapping Data
    16 experiments
Strain
Comparison
more
  • SNPs within 2kb
    42 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_102896
protein coding gene Chr7:126672865-126690426 (-)
129S1/SvImJ MGP_129S1SvImJ_G0032991
protein coding gene Chr7:130956433-130961618 (-)
A/J MGP_AJ_G0032974
protein coding gene Chr7:127491653-127496794 (-)
AKR/J MGP_AKRJ_G0032906
protein coding gene Chr7:130724653-130730484 (-)
BALB/cJ MGP_BALBcJ_G0032979
protein coding gene Chr7:127152398-127155910 (-)
C3H/HeJ MGP_C3HHeJ_G0032689
protein coding gene Chr7:130658095-130661767 (-)
C57BL/6NJ MGP_C57BL6NJ_G0033485
protein coding gene Chr7:136058658-136068211 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030457
protein coding gene Chr7:128681278-128684776 (-)
CAST/EiJ MGP_CASTEiJ_G0032017
protein coding gene Chr7:122434045-122436977 (-)
CBA/J MGP_CBAJ_G0032662
protein coding gene Chr7:140633689-140637303 (-)
DBA/2J MGP_DBA2J_G0032814
protein coding gene Chr7:125471188-125475190 (-)
FVB/NJ MGP_FVBNJ_G0032767
protein coding gene Chr7:125319552-125322585 (-)
LP/J MGP_LPJ_G0032908
protein coding gene Chr7:132425603-132429132 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0032799
protein coding gene Chr7:141822124-141825993 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0033504
protein coding gene Chr7:129735088-129738812 (-)
PWK/PhJ MGP_PWKPhJ_G0031725
protein coding gene Chr7:118461969-118463959 (-)
SPRET/EiJ MGP_SPRETEiJ_G0031571
protein coding gene Chr7:116571004-116575032 (-)
WSB/EiJ MGP_WSBEiJ_G0032130
protein coding gene Chr7:130709237-130712748 (-)



Homology
more
  • Human Ortholog
    SULT1A1, sulfotransferase family 1A member 1
  • Vertebrate Orthologs
    6
  • Human Ortholog
    SULT1A1, sulfotransferase family 1A member 1
    Orthology source: HGNC
  • Synonyms
    HAST1/HAST2, P-PST, PST, ST1A1, ST1A3, STP, STP1, TSPST1
  • Links
    NCBI Gene ID: 6817
    neXtProt AC: NX_P50225
    UniProt: P50225

  • Chr Location
    16p11.2; chr16:28605587-28623586 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    3 phenotypes from multigenic genotypes
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit decrease hepatic DNA adduct formation induced by methyleugenol.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000030711 Ensembl Gene Model | MGI Sequence Detail 3568 C57BL/6J ±  kb
    transcript ENSMUST00000106373 Ensembl | MGI Sequence Detail 1289 Not Applicable  
    polypeptide ENSMUSP00000101981 Ensembl | MGI Sequence Detail 291 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 56
      cDNA 56

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGD-MRK-14633, MGD-MRK-23730, MGI:2141894
    References
    more
    • Summaries
      All 52
      Developmental Gene Expression 2
      Gene Ontology 5
      Phenotypes 7
    • Earliest
      J:2300 Charles CH, et al., cDNA sequence of a growth factor-inducible immediate early gene and characterization of its encoded protein. Oncogene. 1992 Jan;7(1):187-90
    • Latest
      J:217578 Bendadani C, et al., Determination of sulfotransferase forms involved in the metabolic activation of the genotoxicant 1-hydroxymethylpyrene using bacterially expressed enzymes and genetically modified mouse models. Chem Res Toxicol. 2014 Jun 16;27(6):1060-9

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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    last database update
    11/06/2018
    MGI 6.13
    The Jackson Laboratory