About   Help   FAQ
Lmo1 Gene Detail
Summary
  • Symbol
    Lmo1
  • Name
    LIM domain only 1
  • Synonyms
    Rbtn1, Rbtn-1, Ttg1
  • Feature Type
    protein coding gene
  • IDs
    MGI:102812
    NCBI Gene: 109594
  • Gene Overview
    MyGene.info: LMO1
  • Alliance
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:109138572-109175207 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 57.21 cM
  • Mapping Data
    11 experiments
Strain
Comparison
more
  • SNPs within 2kb
    458 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_102812
protein coding gene Chr7:109138565-109175341 (-)
129S1/SvImJ MGP_129S1SvImJ_G0032839
protein coding gene Chr7:112541866-112579681 (-)
A/J MGP_AJ_G0032823
protein coding gene Chr7:109776281-109813869 (-)
AKR/J MGP_AKRJ_G0032754
protein coding gene Chr7:112503397-112541090 (-)
BALB/cJ MGP_BALBcJ_G0032827
protein coding gene Chr7:109472118-109505276 (-)
C3H/HeJ MGP_C3HHeJ_G0032537
protein coding gene Chr7:112558710-112602646 (-)
C57BL/6NJ MGP_C57BL6NJ_G0033333
protein coding gene Chr7:117237776-117269342 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030306
protein coding gene Chr7:111356968-111393321 (-)
CAST/EiJ MGP_CASTEiJ_G0031865
protein coding gene Chr7:104077584-104111793 (-)
CBA/J MGP_CBAJ_G0032510
protein coding gene Chr7:121068776-121103446 (-)
DBA/2J MGP_DBA2J_G0032662
protein coding gene Chr7:107888139-107919791 (-)
FVB/NJ MGP_FVBNJ_G0032615
protein coding gene Chr7:107733234-107770408 (-)
LP/J MGP_LPJ_G0032756
protein coding gene Chr7:114097490-114130717 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0032647
protein coding gene Chr7:122739753-122774474 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0033354
protein coding gene Chr7:111532684-111566079 (-)
PWK/PhJ MGP_PWKPhJ_G0031572
protein coding gene Chr7:100643885-100722927 (-)
SPRET/EiJ MGP_SPRETEiJ_G0031420
protein coding gene Chr7:98167231-98253409 (-)
WSB/EiJ MGP_WSBEiJ_G0031978
protein coding gene Chr7:112365177-112400523 (-)



Homology
more
  • Human Ortholog
    LMO1, LIM domain only 1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    LMO1, LIM domain only 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    RBTN1, RHOM1, TTG1
  • Links
    NCBI Gene ID: 4004
    neXtProt AC: NX_P25800
    UniProt: P25800

  • Chr Location
    11p15.4; chr11:8224304-8268635 (-)  GRCh38.p7

Human Diseases
less
  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 2 alleles in 1 genetic background
    15 phenotypes from multigenic genotypes
    17 phenotype references
  • All Mutations and Alleles
    7
  • Chemically induced (other)
    1
  • Radiation induced
    1
  • Targeted
    4
  • Transgenic
    1
  • Genomic Mutations
    2 involving Lmo1
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
Homozygous mutant mice show no overt phenotype.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000036111 Ensembl Gene Model | MGI Sequence Detail 36636 C57BL/6J ±  kb
transcript ENSMUST00000036992 Ensembl | MGI Sequence Detail 1282 Not Applicable  
polypeptide ENSMUSP00000037079 Ensembl | MGI Sequence Detail 156 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 51
    Genomic 5
    cDNA 37
    Primer pair 7
    Other 2

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-13796, MGD-MRK-13799, MGD-MRK-19720
References
more
  • Summaries
    All 92
    Developmental Gene Expression 36
    Diseases 1
    Gene Ontology 7
    Phenotypes 17
  • Earliest
    J:15547 McGuire EA, et al., The t(11;14)(p15;q11) in a T-cell acute lymphoblastic leukemia cell line activates multiple transcripts, including Ttg-1, a gene encoding a potential zinc finger protein. Mol Cell Biol. 1989 May;9(5):2124-32
  • Latest
    J:261809 Mayer C, et al., Developmental diversification of cortical inhibitory interneurons. Nature. 2018 Mar 22;555(7697):457-462

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/06/2018
MGI 6.13
The Jackson Laboratory