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Lmo1 Gene Detail
Summary
  • Symbol
    Lmo1
  • Name
    LIM domain only 1
  • Synonyms
    Rbtn1, Rbtn-1, Ttg1
  • Feature Type
    protein coding gene
  • IDs
    MGI:102812
    NCBI Gene: 109594
  • Gene Overview
    MyGene.info: LMO1
Location & Maps
more
  • Sequence Map
    Chr7:109138572-109175207 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      36636 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    LMO1, LIM domain only 1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    LMO1, LIM domain only 1
    Orthology source: HGNC, HomoloGene
  • Synonyms
    RBTN1, RHOM1, TTG1
  • Links
    NCBI Gene ID: 4004
    neXtProt AC: NX_P25800

  • Chr Location
    11p15; chr11:8224304-8268635 (-)  GRCh38.p2

Human Diseases
less
  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 2 alleles in 1 genetic background
    15 phenotypes from multigenic genotypes
    15 phenotype references
  • All Mutations and Alleles
    7
  • Chemically induced (other)
    1
  • Radiation induced
    1
  • Targeted
    4
  • Transgenic
    1
  • Genomic Mutations
    2 involving Lmo1
  • Incidental Mutations
    APF
Homozygous mutant mice show no overt phenotype.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000060098 VEGA Gene Model | MGI Sequence Detail 36636 C57BL/6J ±  kb
transcript OTTMUST00000147092 VEGA | MGI Sequence Detail 1282 Not Applicable  
polypeptide OTTMUSP00000076535 VEGA | MGI Sequence Detail 156 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    458 from dbSNP Build 142
  • RFLP
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000009862 rhombotin-1
  • InterPro Domains
    IPR001781 Zinc finger, LIM-type
Molecular
Reagents
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  • All nucleic 44
    Genomic 5
    cDNA 33
    Primer pair 5
    Other 1

    Microarray probesets 3
Other
Accession IDs
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MGD-MRK-13796, MGD-MRK-13799, MGD-MRK-19720
References
more
  • Summaries
    All 79
    Developmental Gene Expression 35
    Diseases 1
    Gene Ontology 8
    Phenotypes 15
  • Earliest
    J:15547 McGuire EA, et al., The t(11;14)(p15;q11) in a T-cell acute lymphoblastic leukemia cell line activates multiple transcripts, including Ttg-1, a gene encoding a potential zinc finger protein. Mol Cell Biol. 1989 May;9(5):2124-32
  • Latest
    J:215487 Thompson CL, et al., A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory