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Tgfb1i1
Gene Detail
Symbol

Name
ID
Tgfb1i1
transforming growth factor beta 1 induced transcript 1
MGI:102784
Synonyms
ARA55, hic-5, TSC-5
Feature Type
protein coding gene
Genetic Map
Chromosome 7
70.07 cM, cytoband F1-F3
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr7:128246812-128253712 bp, + strand
From VEGA annotation of GRCm38

  6901 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:7572  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

Protein SuperFamily: leupaxin
Gene Tree: Tgfb1i1

Human
homologs
Human Homolog TGFB1I1, transforming growth factor beta 1 induced transcript 1
NCBI Gene ID 7041
neXtProt AC  NX_O43294
Human Synonyms  ARA55, HIC5, HIC-5, TSC-5
Human Chr (Location)  16p11.2; chr16:31472155-31477960 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Tgfb1i1 interacts with 198 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (29 annotations)
Process cell differentiation, cell fate commitment, ...
Component cell junction, cytoplasm, ...
Function androgen receptor binding, I-SMAD binding, ...
External Resources: FuncBase
Expression
Literature Summary: (14 records)
Data Summary: Results (195)    Tissues (177)    Images (23)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 195
cDNA source data(63)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(68) Genomic(2) cDNA(64) Primer pair(1) Other(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000036582 (Evidence)
Ensembl Gene ModelENSMUSG00000030782 (Evidence)
Entrez Gene21804 (Evidence)
UniGene3248
DFCITC1594764, TC1594720, TC1579623, TC1597528
DoTSDT.110979202, DT.87040119, DT.110979205, DT.526240, DT.110979214, DT.110979206, DT.110979212, DT.110979210, DT.94295606, DT.91340091, DT.99867373
NIA Mouse Gene IndexU008831
Consensus CDS ProjectCCDS21893.2
International Mouse Knockout Project StatusTgfb1i1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000036582 VEGA Gene Model | MGI Sequence Detail 6901 C57BL/6J ±  kb
transcript OTTMUST00000093807 VEGA | MGI Sequence Detail 1800 Not Applicable 
polypeptide OTTMUSP00000052124 VEGA | MGI Sequence Detail 483 Not Applicable 

For the selected sequences
All sequences(102) RefSeq(16) UniProt(7)
Polymorphisms
SNPs within 2kb(89 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR017305 Leupaxin
InterPro IPR001781 Zinc finger, LIM-type
Protein Ontology PR:000016286 transforming growth factor beta-1-induced transcript 1 protein
References
(Earliest) J:15692 Shibanuma M, et al., Cloning from a mouse osteoblastic cell line of a set of transforming-growth-factor-beta 1-regulated genes, one of which seems to encode a follistatin-related polypeptide. Eur J Biochem. 1993 Oct 1;217(1):13-9
(Latest) J:196351 Perisic L, et al., Plekhh2, a novel podocyte protein downregulated in human focal segmental glomerulosclerosis, is involved in matrix adhesion and actin dynamics. Kidney Int. 2012 Nov;82(10):1071-83
All references(59)
Other
accession IDs
MGD-MRK-19692

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory