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Tgfb1i1
Gene Detail
Symbol

Name
ID
Tgfb1i1
transforming growth factor beta 1 induced transcript 1
MGI:102784
Synonyms
ARA55, hic-5, TSC-5
Feature Type
protein coding gene
Genetic Map
Chromosome 7
70.07 cM, cytoband F1-F3
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr7:128246812-128253712 bp, + strand
From VEGA annotation of GRCm38

  6901 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:7572  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

HCOP human homology predictions: TGFB1I1
Protein SuperFamily: leupaxin
Gene Tree: Tgfb1i1

Human
homologs
TGFB1I1, transforming growth factor beta 1 induced transcript 1
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 7041
neXtProt AC: NX_O43294

Human Synonyms: ARA55, HIC5, HIC-5, TSC-5

Human Chr (Location): 16p11.2; chr16:31472155-31477960 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Tgfb1i1 interacts with 197 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (29 annotations)
Process cell differentiation, cell fate commitment, ...
Component cell junction, cytoplasm, ...
Function androgen receptor binding, I-SMAD binding, ...
External Resources: FuncBase
Expression
Literature Summary: (15 records)
Data Summary: Results (195)    Tissues (177)    Images (23)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 195
cDNA source data(63)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase tgfb1i1    NEW 
Molecular
reagents
All nucleic(68) Genomic(2) cDNA(64) Primer pair(1) Other(1)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000036582 (Evidence)
Ensembl Gene Model ENSMUSG00000030782 (Evidence)
Entrez Gene 21804 (Evidence)
UniGene 3248
DFCI TC1579623, TC1594720, TC1594764, TC1597528
DoTS DT.110979202, DT.110979205, DT.110979206, DT.110979210, DT.110979212, DT.110979214, DT.526240, DT.87040119, DT.91340091, DT.94295606, DT.99867373
NIA Mouse Gene Index U008831
Consensus CDS Project CCDS21893.2
International Mouse Phenotyping Consortium Status Tgfb1i1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000036582 VEGA Gene Model | MGI Sequence Detail 6901 C57BL/6J ±  kb
transcript OTTMUST00000093807 VEGA | MGI Sequence Detail 1800 Not Applicable 
polypeptide OTTMUSP00000052124 VEGA | MGI Sequence Detail 483 Not Applicable 

For the selected sequences
All sequences(104) RefSeq(21) UniProt(4)
Polymorphisms
SNPs within 2kb(89 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR017305 Leupaxin
InterPro IPR001781 Zinc finger, LIM-type
Protein Ontology PR:000016286 transforming growth factor beta-1-induced transcript 1 protein
References
(Earliest) J:15692 Shibanuma M, et al., Cloning from a mouse osteoblastic cell line of a set of transforming-growth-factor-beta 1-regulated genes, one of which seems to encode a follistatin-related polypeptide. Eur J Biochem. 1993 Oct 1;217(1):13-9
(Latest) J:221298 Wang Y, et al., Deletion of yes-associated protein (YAP) specifically in cardiac and vascular smooth muscle cells reveals a crucial role for YAP in mouse cardiovascular development. Circ Res. 2014 Mar 14;114(6):957-65
All references(60)
Other
accession IDs
MGD-MRK-19692

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/18/2015
MGI 6.0
The Jackson Laboratory