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Syt4 Gene Detail
Summary
  • Symbol
    Syt4
  • Name
    synaptotagmin IV
  • Feature Type
    protein coding gene
  • IDs
    MGI:101759
    NCBI Gene: 20983
  • Gene Overview
    MyGene.info: SYT4
Location & Maps
more
  • Sequence Map
    Chr18:31437808-31447415 bp, - strand
  • From NCBI annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      9608 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 18, 17.75 cM
  • Mapping Data
    6 experiments
Homology
more
  • Human Ortholog
    SYT4, synaptotagmin 4
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SYT4, synaptotagmin 4
    Orthology source: HomoloGene
  • Synonyms
    HsT1192
  • Links
    NCBI Gene ID: 6860
    neXtProt AC: NX_Q9H2B2

  • Chr Location
    18q12.3; chr18:43267892-43277650 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygotes for a targeted null mutation exhibit impairments in motor coordination, contextual fear conditioning, and social transmission of food preference.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 20983 NCBI Gene Model | MGI Sequence Detail 9608 C57BL/6J ±  kb
transcript NM_009308 RefSeq | MGI Sequence Detail 3901 C57BL/6  
polypeptide P40749 UniProt | EBI | MGI Sequence Detail 425 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    25 from dbSNP Build 142
  • RFLP
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 18
    cDNA 15
    Primer pair 2
    Other 1

    Microarray probesets 5
Other
Accession IDs
less
MGD-MRK-18565
References
more
  • Summaries
    All 46
    Developmental Gene Expression 7
    Gene Ontology 8
    Phenotypes 8
  • Earliest
    J:1973 Willison K, The mouse Brachyury gene and mesoderm formation. Trends Genet. 1990 Apr;6(4):104-5
  • Latest
    J:230224 Aoki H, et al., Neonatal lethality of neural crest cell-specific Rest knockout mice is associated with gastrointestinal distension caused by aberrations of myenteric plexus. Genes Cells. 2014 Oct;19(10):723-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/15/2016
MGI 6.04
The Jackson Laboratory