Mapping Data Summary

• Symbol: Il2
• Name: interleukin 2
• ID: MGI:96548
• Chromosome: 3

35 mapping experiments

Experiment Type	Details	Chromosome	Reference
CROSS	Cross Type: Backcross Mapping Panel: JAX (BSS)	3	J:45881 Alli C, et al., Linkage mapping of Csrp to proximal mouse chromosome 3. Mamm Genome. 1998 Feb;9(2):172-3
CROSS	Cross Type: Backcross Mapping Panel: JAX (BSS)	3	J:69574 Biggs III WH, et al., Identification and characterization of members of the FKHR (FOX O) subclass of winged-helix transcription factors in the mouse. Mamm Genome. 2001 Jun;12(6):416-25
CROSS	Cross Type: Backcross Mapping Panel: Kozak FvC58 + FvSpr	3	J:33372 Bronstein JM, et al., Chromosomal localization of murine and human oligodendrocyte-specific protein genes. Genomics. 1996 Jun 1;34(2):255-7
CROSS	Cross Type: Backcross	3	J:33372 Bronstein JM, et al., Chromosomal localization of murine and human oligodendrocyte-specific protein genes. Genomics. 1996 Jun 1;34(2):255-7
CROSS	Cross Type: Backcross Mapping Panel: Kozak FvC58	3	J:41327 Filie JD, et al., Genetic mapping of the mouse ferritin light chain gene and 11 pseudogenes on 11 mouse chromosomes. Mamm Genome. 1998 Feb;9(2):111-3
CROSS	Cross Type: Backcross Mapping Panel: JAX (BSS)	3	J:37801 Jin M, et al., Mapping to mouse chromosome 3 of the gene encoding latexin (Lxn) expressed in neocortical neurons in a region-specific manner. Genomics. 1997 Feb 1;39(3):419-21
CROSS	Cross Type: Backcross	3	J:15194 Knapp LT, et al., Corticotropin-releasing hormone (Crh) maps to mouse chromosome 3. Mamm Genome. 1993;4(10):615-7
CROSS	Cross Type: Backcross	3	J:31182 Rodriguez-Garcia MI, et al., Mouse annexin V chromosomal localization, cDNA sequence conservation, and molecular evolution. Genomics. 1996 Jan 15;31(2):151-7
CROSS	Cross Type: Backcross	3	J:3351 Todd JA, et al., Genetic analysis of autoimmune type 1 diabetes mellitus in mice [see comments]. Nature. 1991 Jun 13;351(6327):542-7
CROSS	Cross Type: Backcross Mapping Panel: JAX (BSS)	3	J:49394 Yamazaki K, et al., Genetic mapping of mouse transient receptor potential (Trrp) genes responsible for capacitative calcium entry channels to chromosomes 3, 7, 9, and X. Genomics. 1998 Jul 15;51(2):303-5
HYBRID		3	J:9398 D'Eustachio P, et al., The IL-4 gene maps to chromosome 11, near the gene encoding IL-3. J Immunol. 1988 Nov 1;141(9):3067-71
IN SITU	Band: B-C	3	J:3350 Webb GC, et al., Mapping the gene for murine T-cell growth factor, Il-2, to bands B-C on chromosome 3 and for the alpha chain of the IL2-receptor, Il-2ra, to bands A2-A3 on chromosome 2. Cytogenet Cell Genet. 1990;54(3-4):164-8
RI	RI/RC Set: AKXD	3	J:459 Hearne CM, et al., Additional microsatellite markers for mouse genome mapping. Mamm Genome. 1991;1(4):273-82
RI	RI/RC Set: BXD	3	J:459 Hearne CM, et al., Additional microsatellite markers for mouse genome mapping. Mamm Genome. 1991;1(4):273-82
TEXT		3	J:39376 Denny P, et al., Mapping of the IDDM locus Idd3 to a 0.35-cM interval containing the interleukin-2 gene. Diabetes. 1997 Apr;46(4):695-700
TEXT		3	J:63571 Haddad R, et al., Restriction landmark genomic scanning of mouse liver tumors for gene amplification: overexpression of cyclin A2. Biochem Biophys Res Commun. 2000 Jul 21;274(1):188-96
TEXT		3	J:33172 Yui MA, et al., Production of congenic mouse strains carrying NOD-derived diabetogenic genetic intervals: an approach for the genetic dissection of complex traits. Mamm Genome. 1996 May;7(5):331-4
TEXT-Congenic		3	J:28947 Mcaleer MA, et al., Crosses of NOD mice with the related NON strain: A polygenic model for IDDM. Diabetes. 1995 OCT;44(10):1186-1195
TEXT-Cytogenetic Localization		3	J:3352 Fiorentino L, et al., Assignment of the interleukin-2 locus to mouse chromosome 3. Genomics. 1989 Oct;5(3):651-3
TEXT-Genetic Cross		3	J:39376 Denny P, et al., Mapping of the IDDM locus Idd3 to a 0.35-cM interval containing the interleukin-2 gene. Diabetes. 1997 Apr;46(4):695-700
TEXT-Physical Mapping		3	J:39376 Denny P, et al., Mapping of the IDDM locus Idd3 to a 0.35-cM interval containing the interleukin-2 gene. Diabetes. 1997 Apr;46(4):695-700
TEXT-QTL		3	J:75908 Boulard O, et al., Genetic analysis of autoimmune sialadenitis in nonobese diabetic mice: a major susceptibility region on chromosome 1. J Immunol. 2002 Apr 15;168(8):4192-201
TEXT-QTL		3	J:128900 Cha S, et al., Two NOD Idd-associated intervals contribute synergistically to the development of autoimmune exocrinopathy (Sjogren's syndrome) on a healthy murine background. Arthritis Rheum. 2002 May;46(5):1390-8
TEXT-QTL		3	J:129916 Cha S, et al., IDD3 and IDD5 alleles from nod mice mediate Sjogren's syndrome-like autoimmunity. Adv Exp Med Biol. 2002;506(Pt B):1035-9
TEXT-QTL		3	J:52572 Encinas JA, et al., QTL influencing autoimmune diabetes and encephalomyelitis map to a 0.15-cM region containing Il2. Nat Genet. 1999 Feb;21(2):158-60
TEXT-QTL		3	J:98123 Geiger H, et al., Age- and stage-specific regulation patterns in the hematopoietic stem cell hierarchy. Blood. 2001 Nov 15;98(10):2966-72
TEXT-QTL		3	J:99466 Ikegami H, et al., Genetic dissection of type 1 diabetes susceptibility gene, Idd3, by ancestral haplotype congenic mapping. Ann N Y Acad Sci. 2002 Apr;958:325-8
TEXT-QTL		3	J:106844 Lundholm M, et al., Defective induction of CTLA-4 in the NOD mouse is controlled by the NOD allele of Idd3/IL-2 and a novel locus (Ctex) telomeric on chromosome 1. Diabetes. 2006 Feb;55(2):538-44
TEXT-QTL		3	J:61763 Lyons PA, et al., Congenic mapping of the type 1 diabetes locus, Idd3, to a 780-kb region of mouse chromosome 3: identification of a candidate segment of ancestral DNA by haplotype mapping. Genome Res. 2000 Apr;10(4):446-53
TEXT-QTL		3	J:67658 Mitsos LM, et al., Genetic control of susceptibility to infection with Mycobacterium tuberculosis in mice. Genes Immun. 2000 Dec;1(8):467-77
TEXT-QTL		3	J:57246 Morel L, et al., Epistatic modifiers of autoimmunity in a murine model of lupus nephritis. Immunity. 1999 Aug;11(2):131-9
TEXT-QTL		3	J:129282 Nguyen C, et al., Sjogren's syndrome-like disease of C57BL/6.NOD-Aec1 Aec2 mice: gender differences in keratoconjunctivitis sicca defined by a cross-over in the chromosome 3 Aec1 locus. Scand J Immunol. 2006 Sep;64(3):295-307
TEXT-QTL		3	J:108210 Podolin PL, et al., Differential glycosylation of interleukin 2, the molecular basis for the NOD Idd3 type 1 diabetes gene?. Cytokine. 2000 May;12(5):477-82
TEXT-QTL		3	J:31314 Teuscher C, et al., Aod2, the locus controlling development of atrophy in neonatal thymectomy-induced autoimmune ovarian dysgenesis, co-localizes with Il2, Fgfb, and Idd3. J Exp Med. 1996 Feb 1;183(2):631-7
TEXT-QTL-Candidate Genes		3	J:86885 Ikegami H, et al., Congenic mapping and candidate sequencing of susceptibility genes for Type 1 diabetes in the NOD mouse. Ann N Y Acad Sci. 2003 Nov;1005:196-204