Mapping Data Summary

• Symbol: Pla2g2a
• Name: phospholipase A2, group IIA (platelets, synovial fluid)
• ID: MGI:104642
• Chromosome: 4

15 mapping experiments

Experiment Type	Details	Chromosome	Reference
CROSS	Cross Type: Backcross	4	J:37223 Gould KA, et al., Genetic evaluation of candidate genes for the Mom1 modifier of intestinal neoplasia in mice. Genetics. 1996 Dec;144(4):1777-85
CROSS	Cross Type: Backcross	4	J:26137 MacPhee M, et al., The secretory phospholipase A2 gene is a candidate for the Mom1 locus, a major modifier of ApcMin-induced intestinal neoplasia. Cell. 1995 Jun 16;81(6):957-66
CROSS	Cross Type: Backcross Mapping Panel: UCLA (BSB)	4	J:31958 Tischfield JA, et al., Low-molecular-weight, calcium-dependent phospholipase A2 genes are linked and map to homologous chromosome regions in mouse and human. Genomics. 1996 Mar 15;32(3):328-33
CROSS	Cross Type: Backcross Mapping Panel: UCLA (BSB)	4	J:34178 Welch CL, et al., Genetic regulation of cholesterol homeostasis: chromosomal organization of candidate genes. J Lipid Res. 1996 Jul;37(7):1406-21
TEXT		4	J:15703 Dietrich WF, et al., Genetic identification of Mom-1, a major modifier locus affecting Min-induced intestinal neoplasia in the mouse. Cell. 1993 Nov 19;75(4):631-9
TEXT-Physical Mapping		4	J:71658 Cool M, et al., Elevated frequency of loss of heterozygosity in mammary tumors arising in mouse mammary tumor virus/neu transgenic mice. Cancer Res. 1999 May 15;59(10):2438-44
TEXT-Physical Mapping		4	J:42722 Cormier RT, et al., Secretory phospholipase Pla2g2a confers resistance to intestinal tumorigenesis [see comments]. Nat Genet. 1997 Sep;17(1):88-91
TEXT-QTL		4	J:63266 Cormier RT, et al., The Mom1AKR intestinal tumor resistance region consists of Pla2g2a and a locus distal to D4Mit64. Oncogene. 2000 Jun 29;19(28):3182-92
TEXT-QTL		4	J:90251 Fijneman RJ, et al., Genetic analysis of macrophage characteristics as a tool to identify tumor susceptibility genes: mapping of three macrophage-associated risk inflammatory factors, marif1, marif2, and marif3. Cancer Res. 2004 May 15;64(10):3458-64
TEXT-QTL		4	J:22501 Lee GH, et al., Identification of hepatocarcinogen-resistance genes in DBA/2 mice. Genetics. 1995 Jan;139(1):387-95
TEXT-QTL		4	J:95917 Lipoldova M, et al., Novel loci controlling lymphocyte proliferative response to cytokines and their clustering with loci controlling autoimmune reactions, macrophage function and lung tumor susceptibility. Int J Cancer. 2005 Apr 10;114(3):394-9
TEXT-QTL		3	J:100634 Wheeler FC, et al., QTL mapping in a mouse model of cardiomyopathy reveals an ancestral modifier allele affecting heart function and survival. Mamm Genome. 2005 Jun;16(6):414-23
TEXT-QTL-Candidate Genes		4	J:109420 de Buhr MF, et al., Cd14, Gbp1, and Pla2g2a: three major candidate genes for experimental IBD identified by combining QTL and microarray analyses. Physiol Genomics. 2006 May 16;25(3):426-34
TEXT-Radiation Hybrid		4	J:68900 The Jackson Laboratory Mouse Radiation Hybrid Database, Mouse T31 Radiation Hybrid Data Load. Database Release. 2004;
TEXT-Radiation Hybrid		4	J:58155 Valentin E, et al., On the diversity of secreted phospholipases A(2). Cloning, tissue distribution, and functional expression of two novel mouse group II enzymes. J Biol Chem. 1999 Oct 29;274(44):31195-202