Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  11
• Reference
  J:36997 Fijneman RJ, et al., Complex interactions of new quantitative trait loci, Sluc1, Sluc2, Sluc3, and Sluc4, that influence the susceptibility to lung cancer in the mouse. Nat Genet. 1996 Dec;14(4):465-7
• ID
  MGI:48007

Genes

Gene	Assay Type
D11Mit15	PCR amplified length variant
Sluc4	resistance/susceptibility
D11Mit41	reported elsewhere
Rara	reported elsewhere

Notes

• Experiment
  Lung tissue of N-ethyl-N-nitrosourea treated F2 progeny of an (OcB-9/Dem x O20/A)F1 intercross was microscopically analyzed for the presence and size of tumors. The progeny were genotyped by PCR. Statistical analysis indicated the presence of a locus influencing susceptibility to lung cancer (Sluc4) on mouse Chromosome 11. The QTL likelihood plot indicates a peak near D11Mit15. The following order of loci was reported: D11Mit15 - Sluc4 - D11Mit41 - Rara.