Mapping Data

Experiment

• Experiment
  CROSS
• Chromosome
  2
• Reference
  J:32931 Siracusa LD, et al., A tandem duplication within the fibrillin 1 gene is associated with the mouse tight skin mutation. Genome Res. 1996 Apr;6(4):300-13
• ID
  MGI:46949

Genes

Gene	Allele	Assay Type	Description
Fbn1		Southern analysis	M-10
Fbn1	Fbn1^Tsk	visible phenotype

Notes

• Reference
  Authors show that a tadem duplication within Fbn1 is associated with the Tsk mutant phenotype. This data strongly suggest that Tsk is an allele of Fbn1.

CROSS

• Type
  Intercross
• Female Parent
  <b> <b>/<s> <s>
• Strain
  (C57BL/6-Bloc1s6>+ x C57BL/6-Bloc1s6 +/+ Fbn1)F1
• Male Parent
  <b> <b>/<s> <s>
• Strain
  (C57BL/6-Bloc1s6>+ x C57BL/6-Bloc1s6 +/+ Fbn1)F1
• Allele 1
  b from C57BL/6J-Bloc1s6
• Allele 2
  s from C57BL/6-Bloc1s6 Fbn1/Bloc1s6 +

2x2 Data Reported

Marker 1	Marker 2	# Recombinants	# Parentals
Fbn1	Fbn1	0	86