Mapping Data

Experiment

• Experiment
  CROSS
• Chromosome
  2
• Reference
  J:32931 Siracusa LD, et al., A tandem duplication within the fibrillin 1 gene is associated with the mouse tight skin mutation. Genome Res. 1996 Apr;6(4):300-13
• ID
  MGI:46946

Genes

Gene	Allele	Assay Type	Description
Fbn1		Southern analysis	M1-10
Fbn1	Fbn1^Tsk	visible phenotype

Notes

• Reference
  Authors show that a tadem duplication within Fbn1 is associated with the Tsk mutant phenotype. This data strongly suggest that Tsk is an allele of Fbn1.

CROSS

• Type
  Backcross, sexes unspecified or combined
• Female Parent
  <c> <c>/<b> <b>
• Strain
  (CAST/EiJ x C57BL/6J-Bloc1s6 +/+ Fbn1)F1
• Male Parent
  <c> <c>/<c> <c>
• Strain
  CAST/EiJ
• Allele 1
  c from CAST/EiJ
• Allele 2
  b from C57BL/6J

2x2 Data Reported

Marker 1	Marker 2	# Recombinants	# Parentals
Fbn1	Fbn1	0	168

Statistics

Marker 1	Marker 2	# Recombinants	Total	% Recombinants	Std Error
Fbn1	Fbn1	0	168	0.000	0.000