Mapping Data

Experiment

• Experiment
  TEXT
• Chromosome
  4
• Reference
  J:22054 Hegi ME, et al., Allelotype analysis of mouse lung carcinomas reveals frequent allelic losses on chromosome 4 and an association between allelic imbalances on chromosome 6 and K-ras activation. Cancer Res. 1994 Dec 1;54(23):6257-64
• ID
  MGI:45107

Genes

Gene	Assay Type
Ifna	PCR amplified length variant
D4Nds2	PCR amplified length variant

Notes

• Experiment
  Sets of induced lung carcinomas from (C57BL/6J x C3H/HeJ)F1 and (A/J x C3H/HeJ)F1 mice were analyzed for loss of heterozygosity (LOH). The analysis indicated that a region of mouse Chromosome 4 may include a candidate for a tumor suppressor gene. This region is bounded proximally by Ifa and distally by D4Nds2. Authors suggested that the gene involved may be the mouse homologue of MTS1 which maps to 9p in humans.