Mapping Data

Experiment

• Experiment
  CROSS
• Chromosome
  XY
• Reference
  J:8945 Nagamine CM, et al., Linkage of the murine steroid sulfatase locus, Sts, to sex reversed, Sxr: a genetic and molecular analysis. Nucleic Acids Res. 1987 Nov 25;15(22):9227-38
• ID
  MGI:43238

Genes

Gene	Assay Type
Sts	enzyme activity
Tp(Y)1Ct	visible phenotype

Notes

• Reference
  Authors stated they found a functional allele of Sts in the pseudoautosomal region of the Y Chromosome. There were no double recombinations in linkage analysis between Sts and Tp(Y)1Ct with Tdy.
• Experiment
  Tp(Y)1Ct is commonly called Sxr. Mice carrying the Sxr mutation were backcrossed onto a 129/Sv inbred. At the third generation, the XYSxr genotype were mated to the C3H/An. Data from the cross also indicates that Sts and Sxr were transferred in tandem from the pseudoautosomal region of the Y Chromosome.

CROSS

• Type
  Backcross, male
• Female Parent
  <c> <c>/<c> <c>
• Strain
  C3H/An
• Male Parent
  <c> <c>/<s> <s>
• Strain
  (C3H/An x X/Y-Tp(Y)1Ct)F1-X/Y-Tp(Y)1Ct
• Allele 1
  c from C3H/An
• Allele 2
  s from STOCK Tp(Y)1Ct

2x2 Data Reported

Marker 1	Marker 2	# Recombinants	# Parentals
Sts	Tp(Y)1Ct	1	102

Statistics

Marker 1	Marker 2	# Recombinants	Total	% Recombinants	Std Error
Sts	Tp(Y)1Ct	1	103	0.971	0.966