Mapping Data

Experiment

• Experiment
  TEXT-Genetic Cross
• Chromosome
  16
• Reference
  J:4377 Gregor P, et al., Chromosomal localization of glutamate receptor genes: relationship to familial amyotrophic lateral sclerosis and other neurological disorders of mice and humans. Proc Natl Acad Sci U S A. 1993 Apr 1;90(7):3053-7
• ID
  MGI:41853

Genes

Gene	Assay Type	Description
App	reported elsewhere	Reeves, et al., Genomics 8:141-148, 1990
Grik1	Southern analysis	pmGluR5
Sod1	reported elsewhere	Reeves, R.H. Cytogenet Cell Genet 44:76-81, 1987

Notes

• Reference
  Cd1 may be Cd1a or Cd1b as identified by a probe from B. Seed, followed here as Cd1. Symbol for glutamate receptor loci have been changed by the Nomenclature Committee (Jan 1994).
• Experiment
  Interval mapping by using three previously defined backcrosses was used to map the locus for Grik1 between App and Sod1 on Chromosome 16. The order from the centromere was given as App - (2.1 cM) - Grik1 - (3.5 cM) - Sod1. The backcrosses used were BALB/cJ x (BALB/cJ x MOLD/Rk)F1; (BALB/cJ x MOLD/Rk)F1 x BALB/cJ and (MOLD/Rk x DW/J)F1 x DW/J.