Mapping Data

Experiment

• Experiment
  CROSS
• Chromosome
  7
• Reference
  J:4101 Nicholls RD, et al., Evaluation of potential models for imprinted and nonimprinted components of human chromosome 15q11-q13 syndromes by fine-structure homology mapping in the mouse. Proc Natl Acad Sci U S A. 1993 Mar 1;90(5):2050-4
• ID
  MGI:41578

Genes

Gene	Assay Type	Description
Myod1	Southern analysis	MYOD1 cDNA
Oca2	Southern analysis	DN10
Mkrn3	Southern analysis	34-1-111
Igf1r	Southern analysis	Igf1r cDNA

Notes

• Reference
  DN34 was used as a probe to isolate both a genomic clone (which hybridizes to D7Hms1) and a cDNA 34-1-111 (which hybridizes to D7H15S9-1 now called Zfp127). Since they are closely linked in humans and 34-1-111 recognizes the DN34 homolog in mouse, the authors suggest that D7Hms1 and D7H15S9-1 are identical.
• Experiment
  Offspring types indicate alleles inherited from F1 parent.
  

CROSS

• Type
  Backcross, female
• Female Parent
  <b> <b> <b> <b>/<s> <s> <s> <s>
• Strain
  (129/Rl-Oca2

  Tyr x M. spretus)F1

• Male Parent
  <b> <b> <b> <b>/<b> <b> <b> <b>
• Strain
  129/Rl-Oca2

  Tyr

• Allele 1
  b from 129/Rl-Oca2

  Tyr

• Allele 2
  s from M. spretus

CROSS Data

MC #mice	Myod1	Oca2	Mkrn3	Igf1r
83	b	b	b	b
77	s	s	s	s
4	b	s	s	s
5	s	b	b	b
0	b	b	s	s
1	s	s	b	b
6	b	b	b	s
5	s	s	s	b
1	b	s	b	b

Statistics

Marker 1	Marker 2	# Recombinants	Total	% Recombinants	Std Error
Myod1	Oca2	10	182	5.495	1.689
Oca2	Mkrn3	2	182	1.099	0.773
Mkrn3	Igf1r	11	182	6.044	1.766