Mapping Data

Experiment

• Experiment
  CROSS
• Chromosome
  16
• Reference
  J:22777 Reeves RH, et al., The mouse neurological mutant weaver maps within the region of chromosome 16 that is homologous to human chromosome 21. Genomics. 1989 Oct;5(3):522-6
• ID
  MGI:38295

Genes

Gene	Allele
App
Sod1
Kcnj6	Kcnj6^wv
Ets2
Mx1

Notes

• Reference
  Revised gene symbol Mx-1 (formerly Mx).
• Experiment
  The following probes were used for DNA analysis: pDS10.1 for App, p61-10 for Sod-1, etsPH1.03 for Ets-2 and a 2.3 kb murine cDNA for Mx-1. Offspring types indicate alleles inherited from segregating parent. Symbol "a" represents C57BL/6-wv/wv alleles and"b" MOLD/Rk.

CROSS

• Type
  Backcross, female
• Female Parent
  <a> <a> wv <a> <a>/<a> Sod-1<a> wv Ets-2<a> Mx-1<a>
• Strain
  C57BL/6-Kcnj6
• Male Parent
  App<b> Sod-1<b> + Ets-2<b> Mx-1<b>/App<a> Sod-1<a> wv Ets-2<a> Mx-1<a>
• Strain
  (C57BL/6-Kcnj6/+ x MOLD/Rk)F1

CROSS Data

MC #mice	App	Sod1	Kcnj6	Ets2	Mx1
43	App<a>	Sod-1<a>	wv	Ets-2<a>	Mx-1<a>
36	App<b>	Sod-1<b>	+	Ets-2<b>	Mx-1<b>
4	App<a>	Sod-1<b>	+	Ets-2<b>	Mx-1<b>
5	App<b>	Sod-1<a>	wv	Ets-2<a>	Mx-1<a>
10	App<a>	Sod-1<a>	+	Ets-2<b>	Mx-1<b>
4	App<b>	Sod-1<b>	wv	Ets-2<a>	Mx-1<a>
0	App<a>	Sod-1<a>	wv	Ets-2<b>	Mx-1<b>
1	App<b>	Sod-1<b>	+	Ets-2<a>	Mx-1<a>
0	App<a>	Sod-1<b>	wv	Ets-2<a>	Mx-1<a>
1	App<b>	Sod-1<a>	+	Ets-2<b>	Mx-1<b>

Statistics

Marker 1	Marker 2	# Recombinants	Total	% Recombinants	Std Error
App	Sod1	10	104	9.615	2.891
Sod1	Kcnj6	15	104	14.423	3.445
Kcnj6	Ets2	1	104	0.962	0.957
Ets2	Mx1	0	104	0.000	0.000