About   Help   FAQ
Mapping Data
Experiment
  • Experiment
    TEXT
  • Chromosome
    6
  • Reference
    J:70821 Poltorak A, et al., A point mutation in the il-12rbeta2 gene underlies the il-12 unresponsiveness of lps-defective c57bl/10sccr mice. J Immunol. 2001 Aug 15;167(4):2106-11
  • ID
    MGI:2152401
Genes
GeneAlleleAssay TypeDescription
Il12rb2
Notes
  • Experiment
    A single locus, Ifnm, responsible for defective IL-12 response in C57BL/10ScCr mice mapped to mouse Chromosome 6 in tight linkage with D6Mit356 (LOD = 14.3) and colocalizes with Il12rb2. A (C57BL/10ScCr x 129S2/SvPas)F1 x C57BL/10ScCr backcross was used inthe mapping study. Progenitor strain C57BL/10ScCr is IL-12 defective and is derived from the IL-12 responsive C57BL/10NCr strain. Progenitor strain 129S2/SvPas is IL-12 responsive.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory