LexVision Analysis [version: 05.05.00.05]

Stress Induced Hyperthermia for Project: NIH-1289

Test Description: (SIH) is a measurement of autonomic hyperactivity induced by anxiety-provoking stimuli. The method involves taking two rectal body temperature measurements 10 minutes apart. SIH is determined by subtracting the basal body temperature (T1) from the stress-enhanced temperature (T2). The difference in delta values (T2 - T1 = deltaT) indicates the severity of autonomic hyperactivity or SIH. The rise in body temperature associated with SIH is a sign of anticipatory anxiety to the second rectal body temperature measurement. Lower deltaT values suggest decreased anxiety-like responses.

Results

	Stress-Induced Hyperthermia Analysis data

Mouse Label	Genotype	Age (days)	Stress Temperature	Basal Temperature
M-72	hom	70	37.4	36.0
M-80	hom	70	36.8	36.0
M-83	hom	70	37.0	35.5
M-106	hom	69	35.7	35.7
M-74	wt	70	36.9	34.8
M-76	wt	70	36.4	35.2
M-79	wt	70	35.7	35.2
M-141	wt	69	37.0	35.6
F-95	hom	69	0.0	35.6
F-97	hom	69	0.0	36.2
F-102	hom	69	0.0	35.4
F-120	hom	69	0.0	36.5
F-93	wt	69	0.0	35.7
F-103	wt	69	0.0	35.5
F-104	wt	69	0.0	35.7
F-121	wt	69	0.0	36.6