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Test Description: A large arena (40 cm x 40 cm) with infrared beams at three different levels is used to record rearing, hole poke, and locomotor activity. The animal is placed in the center and its activity is measured for 20 minutes. Data from this test is analyzed in five, 4-minute intervals. The total distance traveled (cm), vertical movement number (rearing), number of hole pokes, and the center:total distance ratio are then graphed.








Results Data
GenotypeMedian Rearing ActivityMedian Hole Poke ActivityMedian Normalized Slope**
+/+ (n=8)43.528.5-1.59
+/- (n=0)   
-/- (n=8)30.025.5-3.87
** Normalized slope is based on total distance traveled.


Genotype Mouse Label % of Total Distance Normalized
Slope
Interval 1
(4 min)
Interval 2
(8 min)
Interval 3
(12 min)
Interval 4
(16 min)
Interval 5
(20 min)
hom M-72 30.52 24.89 18.08 13.84 12.67 -4.68
hom M-80 40.33 28.43 12.89 11.98 6.37 -8.44
hom M-83 37.27 24.37 16.82 11.47 10.08 -6.73
hom F-95 33.82 12.76 20.58 15.96 16.89 -3.07
hom F-97 20.97 15.98 18.3 28.9 15.85 0.27
hom F-102 30.25 12.13 17.46 14.19 25.98 -0.65
hom M-106 15.6 27.13 21.41 23.35 12.51 -1.0
hom F-120 38.34 21.58 15.35 12.31 12.41 -6.11
(hom)   Slope  Median:   -3.88
Mean:   -3.8
wt M-74 18.51 19.94 29.25 13.98 18.32 -0.63
wt M-76 28.92 20.67 14.68 15.64 20.09 -2.27
wt M-79 20.6 21.5 22.85 18.52 16.53 -1.11
wt F-93 20.37 13.51 11.03 22.14 32.96 3.38
wt F-103 30.17 24.5 20.83 15.73 8.77 -5.16
wt F-104 33.61 15.52 16.94 18.2 15.73 -3.31
wt F-121 26.5 19.93 18.53 17.81 17.24 -2.07
wt M-141 21.05 21.91 17.57 17.35 22.12 -0.24
(wt)   Slope  Median:   -1.59
Mean:   -1.43




  Openfield New Analysis data for Project: NIH-1289 - Results        Export Data to Spreadsheet
Mouse Label Genotype Age (days) SAMPLE SAMP DUR TOTAL DIST VACTV VMOVNO V TIME STRNO CTR DIST PSA PRI SAMP DUR PRI SAMP AUX SAMP DUR AUX SAMP
M-72 hom 77 1 240.0 677 5 3 1.6 35 100 P 4 5 0 0
M-72 hom 77 1 240.0 11 9 3.7 4 5
M-72 hom 77 2 240.0 12 8 4.2 4 5
M-72 hom 77 3 240.0 401 23 11 12.8 26 91 P 4 5 0 0
M-72 hom 77 4 240.0 307 8 4 5.4 35 49 P 4 5 0 0
M-72 hom 77 5 240.0 8 5 3.7 4 5
M-72 hom 77 5 240.0 281 30 9 14.5 33 71 P 4 5 0 0
M-72 hom 77 2 240.0 552 12 9 4.0 32 90 P 4 5 0 0
M-72 hom 77 3 240.0 9 5 6.0 4 5
M-72 hom 77 4 240.0 9 7 4.8 4 5
M-80 hom 77 1 240.0 532 15 12 11.7 38 48 P 4 5 0 0
M-80 hom 77 5 240.0 0 0 0.0 4 5
M-80 hom 77 5 240.0 84 1 1 0.5 35 8 P 4 5 0 0
M-80 hom 77 2 240.0 375 26 15 20.1 38 122 P 4 5 0 0
M-80 hom 77 2 240.0 13 10 4.2 4 5
M-80 hom 77 3 240.0 1 1 0.2 4 5
M-80 hom 77 4 240.0 158 9 6 6.9 40 24 P 4 5 0 0
M-80 hom 77 4 240.0 0 0 0.0 4 5
M-80 hom 77 3 240.0 170 12 6 6.8 37 14 P 4 5 0 0
M-80 hom 77 1 240.0 8 6 1.7 4 5
M-83 hom 77 1 240.0 780 23 9 10.6 41 162 P 4 5 0 0
M-83 hom 77 5 240.0 6 3 4.8 4 5
M-83 hom 77 5 240.0 211 8 5 4.7 31 98 P 4 5 0 0
M-83 hom 77 4 240.0 240 3 3 2.4 38 117 P 4 5 0 0
M-83 hom 77 4 240.0 5 3 2.5 4 5
M-83 hom 77 3 240.0 9 5 6.7 4 5
M-83 hom 77 3 240.0 352 6 5 5.1 31 131 P 4 5 0 0
M-83 hom 77 2 240.0 15 9 11.6 4 5
M-83 hom 77 2 240.0 510 7 3 3.5 33 169 P 4 5 0 0
M-83 hom 77 1 240.0 6 6 3.6 4 5
F-95 hom 76 1 240.0 761 26 13 10.4 36 182 P 4 5 0 0
F-95 hom 76 5 240.0 2 1 1.0 4 5
F-95 hom 76 5 240.0 380 18 7 10.1 37 80 P 4 5 0 0
F-95 hom 76 4 240.0 7 6 4.5 4 5
F-95 hom 76 4 240.0 359 15 7 7.7 42 105 P 4 5 0 0
F-95 hom 76 3 240.0 463 8 4 8.9 34 84 P 4 5 0 0
F-95 hom 76 2 240.0 11 6 3.3 4 5
F-95 hom 76 3 240.0 10 6 11.8 4 5
F-95 hom 76 2 240.0 287 10 4 4.7 33 35 P 4 5 0 0
F-95 hom 76 1 240.0 9 6 7.6 4 5
F-97 hom 76 1 240.0 9 8 4.6 4 5
F-97 hom 76 5 240.0 9 7 9.3 4 5
F-97 hom 76 5 240.0 356 14 9 8.6 52 123 P 4 5 0 0
F-97 hom 76 4 240.0 0 0 0.0 4 5
F-97 hom 76 4 240.0 649 12 8 5.8 46 301 P 4 5 0 0
F-97 hom 76 3 240.0 0 0 0.0 4 5
F-97 hom 76 3 240.0 411 1 1 0.4 48 145 P 4 5 0 0
F-97 hom 76 2 240.0 1 1 0.2 4 5
F-97 hom 76 2 240.0 359 2 2 0.0 43 76 P 4 5 0 0
F-97 hom 76 1 240.0 471 2 1 0.3 24 193 P 4 5 0 0
F-102 hom 76 1 240.0 8 7 3.5 4 5
F-102 hom 76 5 240.0 12 10 7.1 4 5
F-102 hom 76 5 240.0 390 0 0 0.0 40 42 P 4 5 0 0
F-102 hom 76 4 240.0 213 0 0 0.0 35 46 P 4 5 0 0
F-102 hom 76 3 240.0 262 3 3 0.8 25 37 P 4 5 0 0
F-102 hom 76 2 240.0 182 2 1 0.7 39 53 P 4 5 0 0
F-102 hom 76 4 240.0 9 8 3.1 4 5
F-102 hom 76 3 240.0 5 4 3.5 4 5
F-102 hom 76 2 240.0 11 7 5.9 4 5
F-102 hom 76 1 240.0 454 1 1 0.1 38 76 P 4 5 0 0
M-106 hom 76 1 240.0 10 6 5.0 4 5
M-106 hom 76 5 240.0 8 6 3.1 4 5
M-106 hom 76 5 240.0 308 22 8 8.0 30 87 P 4 5 0 0
M-106 hom 76 4 240.0 575 25 10 11.9 28 187 P 4 5 0 0
M-106 hom 76 4 240.0 16 7 10.4 4 5
M-106 hom 76 3 240.0 10 7 4.8 4 5
M-106 hom 76 3 240.0 527 16 4 6.6 38 145 P 4 5 0 0
M-106 hom 76 2 240.0 668 23 10 11.3 34 48 P 4 5 0 0
M-106 hom 76 2 240.0 6 5 3.0 4 5
M-106 hom 76 1 240.0 384 11 6 4.9 41 15 P 4 5 0 0
F-120 hom 76 1 240.0 5 5 2.2 4 5
F-120 hom 76 5 240.0 257 2 1 1.0 38 21 P 4 5 0 0
F-120 hom 76 5 240.0 0 0 0.0 4 5
F-120 hom 76 4 240.0 0 0 0.0 4 5
F-120 hom 76 4 240.0 255 0 0 0.0 37 47 P 4 5 0 0
F-120 hom 76 3 240.0 5 4 2.3 4 5
F-120 hom 76 2 240.0 447 4 3 1.9 40 114 P 4 5 0 0
F-120 hom 76 3 240.0 318 1 1 0.0 35 78 P 4 5 0 0
F-120 hom 76 2 240.0 9 7 3.5 4 5
F-120 hom 76 1 240.0 794 2 2 0.3 39 98 P 4 5 0 0
M-74 wt 77 1 240.0 400 26 13 13.7 35 60 P 4 5 0 0
M-74 wt 77 5 240.0 396 18 9 11.7 33 84 P 4 5 0 0
M-74 wt 77 5 240.0 10 7 4.6 4 5
M-74 wt 77 4 240.0 302 10 5 4.4 32 81 P 4 5 0 0
M-74 wt 77 4 240.0 3 2 2.4 4 5
M-74 wt 77 3 240.0 20 12 12.0 4 5
M-74 wt 77 3 240.0 632 28 10 14.7 31 137 P 4 5 0 0
M-74 wt 77 2 240.0 1 1 0.2 4 5
M-74 wt 77 2 240.0 431 10 7 8.7 37 20 P 4 5 0 0
M-74 wt 77 1 240.0 0 0 0.0 4 5
M-76 wt 77 1 240.0 540 37 18 24.8 40 47 P 4 5 0 0
M-76 wt 77 5 240.0 0 0 0.0 4 5
M-76 wt 77 5 240.0 375 22 11 17.1 31 46 P 4 5 0 0
M-76 wt 77 3 240.0 0 0 0.0 4 5
M-76 wt 77 1 240.0 0 0 0.0 4 5
M-76 wt 77 2 240.0 0 0 0.0 4 5
M-76 wt 77 4 240.0 292 21 7 10.0 30 23 P 4 5 0 0
M-76 wt 77 4 240.0 0 0 0.0 4 5
M-76 wt 77 3 240.0 274 11 7 11.4 28 47 P 4 5 0 0
M-76 wt 77 2 240.0 386 20 13 16.4 47 75 P 4 5 0 0
M-79 wt 77 1 240.0 228 33 10 11.1 41 95 P 4 5 0 0
M-79 wt 77 5 240.0 183 35 9 14.6 38 66 P 4 5 0 0
M-79 wt 77 5 240.0 9 7 3.5 4 5
M-79 wt 77 4 240.0 205 27 8 10.2 33 71 P 4 5 0 0
M-79 wt 77 4 240.0 6 4 2.1 4 5
M-79 wt 77 3 240.0 253 42 10 13.8 46 80 P 4 5 0 0
M-79 wt 77 3 240.0 12 6 10.0 4 5
M-79 wt 77 2 240.0 238 36 7 10.2 31 56 P 4 5 0 0
M-79 wt 77 2 240.0 11 7 4.3 4 5
M-79 wt 77 1 240.0 2 1 1.4 4 5
F-93 wt 76 1 240.0 288 0 0 0.0 35 106 P 4 5 0 0
F-93 wt 76 5 240.0 12 9 3.5 4 5
F-93 wt 76 5 240.0 466 1 1 1.0 27 99 P 4 5 0 0
F-93 wt 76 4 240.0 313 0 0 0.0 34 36 P 4 5 0 0
F-93 wt 76 4 240.0 6 4 1.3 4 5
F-93 wt 76 3 240.0 156 2 2 0.0 23 28 P 4 5 0 0
F-93 wt 76 3 240.0 4 2 0.6 4 5
F-93 wt 76 2 240.0 2 1 0.4 4 5
F-93 wt 76 2 240.0 191 1 1 0.4 31 10 P 4 5 0 0
F-93 wt 76 1 240.0 11 10 3.1 4 5
F-103 wt 76 1 240.0 13 10 6.6 4 5
F-103 wt 76 5 240.0 5 3 0.7 4 5
F-103 wt 76 5 240.0 136 0 0 0.0 21 40 P 4 5 0 0
F-103 wt 76 4 240.0 8 7 5.3 4 5
F-103 wt 76 4 240.0 244 5 3 1.6 29 49 P 4 5 0 0
F-103 wt 76 3 240.0 323 10 4 2.9 37 127 P 4 5 0 0
F-103 wt 76 3 240.0 19 14 15.2 4 5
F-103 wt 76 2 240.0 380 8 6 2.6 30 115 P 4 5 0 0
F-103 wt 76 2 240.0 5 5 1.9 4 5
F-103 wt 76 1 240.0 468 4 2 1.1 38 149 P 4 5 0 0
F-104 wt 76 1 240.0 8 7 1.2 4 5
F-104 wt 76 5 240.0 14 7 7.2 4 5
F-104 wt 76 5 240.0 299 15 7 6.9 37 73 P 4 5 0 0
F-104 wt 76 4 240.0 346 12 6 7.5 30 128 P 4 5 0 0
F-104 wt 76 4 240.0 32 13 17.7 4 5
F-104 wt 76 3 240.0 322 17 10 13.3 32 109 P 4 5 0 0
F-104 wt 76 3 240.0 0 0 0.0 4 5
F-104 wt 76 2 240.0 8 4 3.3 4 5
F-104 wt 76 2 240.0 295 6 3 4.7 45 83 P 4 5 0 0
F-104 wt 76 1 240.0 639 15 9 7.8 31 140 P 4 5 0 0
F-121 wt 76 1 240.0 11 6 3.6 4 5
F-121 wt 76 5 240.0 5 4 2.2 4 5
F-121 wt 76 5 240.0 333 22 9 16.9 32 39 P 4 5 0 0
F-121 wt 76 4 240.0 20 10 7.1 4 5
F-121 wt 76 4 240.0 344 10 6 8.0 37 62 P 4 5 0 0
F-121 wt 76 3 240.0 20 13 6.0 4 5
F-121 wt 76 3 240.0 358 13 8 13.6 29 97 P 4 5 0 0
F-121 wt 76 2 240.0 20 13 7.3 4 5
F-121 wt 76 2 240.0 385 12 8 7.8 36 89 P 4 5 0 0
F-121 wt 76 1 240.0 512 20 12 11.0 34 50 P 4 5 0 0
M-141 wt 76 1 240.0 13 9 7.5 4 5
M-141 wt 76 5 240.0 617 45 18 20.2 37 255 P 4 5 0 0
M-141 wt 76 5 240.0 15 10 8.9 4 5
M-141 wt 76 4 240.0 17 10 7.6 4 5
M-141 wt 76 4 240.0 484 59 19 17.9 37 244 P 4 5 0 0
M-141 wt 76 3 240.0 17 9 10.1 4 5
M-141 wt 76 3 240.0 490 37 15 13.3 41 228 P 4 5 0 0
M-141 wt 76 2 240.0 12 9 4.3 4 5
M-141 wt 76 2 240.0 611 53 18 17.7 43 178 P 4 5 0 0
M-141 wt 76 1 240.0 587 24 13 7.5 44 175 P 4 5 0 0
 


Copyright 2005 by Lexicon Genetics Incorporated
Lexicon Phenotypic Analysis software version 05.05.00.05