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Test Description: A large arena (40 cm x 40 cm) with infrared beams at three different levels is used to record rearing, hole poke, and locomotor activity. The animal is placed in the center and its activity is measured for 20 minutes. Data from this test is analyzed in five, 4-minute intervals. The total distance traveled (cm), vertical movement number (rearing), number of hole pokes, and the center:total distance ratio are then graphed.








Results Data
GenotypeMedian Rearing ActivityMedian Hole Poke ActivityMedian Normalized Slope**
+/+ (n=8)43.038.0-3.82
+/- (n=0)   
-/- (n=8)21.029.0-4.12
** Normalized slope is based on total distance traveled.


Genotype Mouse Label % of Total Distance Normalized
Slope
Interval 1
(4 min)
Interval 2
(8 min)
Interval 3
(12 min)
Interval 4
(16 min)
Interval 5
(20 min)
hom F-276 24.61 19.6 19.19 15.84 20.76 -1.15
hom M-279 29.29 26.72 15.86 12.4 15.74 -4.14
hom M-293 20.95 21.14 21.28 14.89 21.75 -0.47
hom M-304 33.13 18.32 18.94 15.7 13.91 -4.11
hom M-310 44.85 22.71 8.13 15.53 8.78 -7.93
hom F-323 25.45 23.17 20.42 17.82 13.14 -3.0
hom F-348 47.54 23.29 13.01 8.57 7.6 -9.46
hom F-365 33.66 30.14 12.92 14.48 8.8 -6.54
(hom)   Slope  Median:   -4.12
Mean:   -4.6
wt F-264 41.48 14.86 12.21 11.85 19.59 -4.68
wt F-299 32.1 19.72 20.38 14.88 12.92 -4.32
wt M-320 18.01 30.1 19.52 15.68 16.69 -1.71
wt M-325 16.04 23.22 18.53 23.68 18.53 0.54
wt F-340 28.56 20.32 20.32 17.3 13.51 -3.31
wt M-341 23.65 27.09 19.55 16.01 13.69 -3.1
wt F-353 34.66 21.89 16.15 17.77 9.53 -5.44
wt M-358 29.28 27.19 23.12 6.87 13.54 -5.18
(wt)   Slope  Median:   -3.82
Mean:   -3.4




  Openfield New Analysis data for Project: NIH-0769 - Results        Export Data to Spreadsheet
Mouse Label Genotype Age (days) SAMPLE SAMP DUR TOTAL DIST VACTV VMOVNO V TIME STRNO CTR DIST PSA PRI SAMP DUR PRI SAMP AUX SAMP DUR AUX SAMP
F-276 hom 79 1 240.0 13 11 5.0 4 5
F-276 hom 79 1 240.0 1016 26 15 14.3 43 161 P 4 5 0 0
F-276 hom 79 2 240.0 809 17 12 15.7 42 130 P 4 5 0 0
F-276 hom 79 3 240.0 14 12 6.8 4 5
F-276 hom 79 4 240.0 654 26 13 17.6 38 142 P 4 5 0 0
F-276 hom 79 5 240.0 10 7 5.9 4 5
F-276 hom 79 5 240.0 857 24 10 10.0 34 306 P 4 5 0 0
F-276 hom 79 3 240.0 792 28 11 10.6 42 185 P 4 5 0 0
F-276 hom 79 2 240.0 8 6 2.7 4 5
F-276 hom 79 4 240.0 6 4 1.9 4 5
M-279 hom 79 1 240.0 456 0 0 0.0 25 66 P 4 5 0 0
M-279 hom 79 5 240.0 14 7 11.1 4 5
M-279 hom 79 5 240.0 245 20 6 7.3 38 128 P 4 5 0 0
M-279 hom 79 3 240.0 9 5 5.2 4 5
M-279 hom 79 2 240.0 9 7 4.9 4 5
M-279 hom 79 2 240.0 416 9 5 4.7 27 37 P 4 5 0 0
M-279 hom 79 4 240.0 14 10 8.8 4 5
M-279 hom 79 4 240.0 193 19 6 9.8 28 77 P 4 5 0 0
M-279 hom 79 3 240.0 247 9 4 5.8 41 94 P 4 5 0 0
M-279 hom 79 1 240.0 6 3 3.5 4 5
M-293 hom 79 1 240.0 6 4 2.6 4 5
M-293 hom 79 5 240.0 13 8 4.3 4 5
M-293 hom 79 5 240.0 466 40 15 19.9 42 226 P 4 5 0 0
M-293 hom 79 4 240.0 319 17 10 6.3 46 160 P 4 5 0 0
M-293 hom 79 4 240.0 5 5 1.6 4 5
M-293 hom 79 3 240.0 22 15 14.7 4 5
M-293 hom 79 3 240.0 456 11 4 4.2 44 216 P 4 5 0 0
M-293 hom 79 1 240.0 449 2 1 0.5 37 90 P 4 5 0 0
M-293 hom 79 2 240.0 453 2 1 1.8 42 165 P 4 5 0 0
M-293 hom 79 2 240.0 18 12 7.7 4 5
M-304 hom 79 1 240.0 8 5 3.9 4 5
M-304 hom 79 5 240.0 12 10 9.1 4 5
M-304 hom 79 5 240.0 202 25 14 17.0 28 74 P 4 5 0 0
M-304 hom 79 4 240.0 228 22 11 13.3 33 56 P 4 5 0 0
M-304 hom 79 4 240.0 8 5 4.7 4 5
M-304 hom 79 3 240.0 13 9 8.1 4 5
M-304 hom 79 3 240.0 275 21 8 10.5 32 89 P 4 5 0 0
M-304 hom 79 2 240.0 266 21 10 11.1 32 148 P 4 5 0 0
M-304 hom 79 2 240.0 23 18 12.0 4 5
M-304 hom 79 1 240.0 481 36 16 16.2 38 82 P 4 5 0 0
M-310 hom 78 1 240.0 618 15 7 7.4 35 96 P 4 5 0 0
M-310 hom 78 5 240.0 0 0 0.0 4 5
M-310 hom 78 5 240.0 121 9 6 5.5 20 9 P 4 5 0 0
M-310 hom 78 4 240.0 6 3 1.9 4 5
M-310 hom 78 4 240.0 214 9 4 5.0 42 41 P 4 5 0 0
M-310 hom 78 3 240.0 112 0 0 0.0 24 8 P 4 5 0 0
M-310 hom 78 3 240.0 1 1 0.1 4 5
M-310 hom 78 2 240.0 313 10 4 5.1 33 50 P 4 5 0 0
M-310 hom 78 2 240.0 0 0 0.0 4 5
M-310 hom 78 1 240.0 12 10 2.9 4 5
F-323 hom 78 1 240.0 6 5 2.1 4 5
F-323 hom 78 5 240.0 253 5 3 2.7 31 72 P 4 5 0 0
F-323 hom 78 5 240.0 1 1 0.3 4 5
F-323 hom 78 4 240.0 8 8 3.9 4 5
F-323 hom 78 4 240.0 343 3 3 1.5 30 91 P 4 5 0 0
F-323 hom 78 3 240.0 3 3 1.9 4 5
F-323 hom 78 2 240.0 10 9 4.5 4 5
F-323 hom 78 3 240.0 393 3 2 1.7 35 78 P 4 5 0 0
F-323 hom 78 2 240.0 446 2 2 2.3 37 68 P 4 5 0 0
F-323 hom 78 1 240.0 490 5 4 3.1 34 155 P 4 5 0 0
F-348 hom 77 1 240.0 4 3 2.6 4 5
F-348 hom 77 5 240.0 142 0 0 0.0 21 24 P 4 5 0 0
F-348 hom 77 5 240.0 0 0 0.0 4 5
F-348 hom 77 4 240.0 0 0 0.0 4 5
F-348 hom 77 4 240.0 160 0 0 0.0 21 3 P 4 5 0 0
F-348 hom 77 3 240.0 2 1 1.1 4 5
F-348 hom 77 3 240.0 243 1 1 0.3 27 17 P 4 5 0 0
F-348 hom 77 2 240.0 7 4 2.4 4 5
F-348 hom 77 2 240.0 435 4 3 0.7 31 45 P 4 5 0 0
F-348 hom 77 1 240.0 888 10 7 3.6 30 109 P 4 5 0 0
F-365 hom 77 1 240.0 2 2 0.1 4 5
F-365 hom 77 5 240.0 1 1 0.1 4 5
F-365 hom 77 5 240.0 260 3 2 1.0 39 38 P 4 5 0 0
F-365 hom 77 3 240.0 0 0 0.0 4 5
F-365 hom 77 2 240.0 1 1 0.1 4 5
F-365 hom 77 3 240.0 382 3 3 0.3 43 90 P 4 5 0 0
F-365 hom 77 4 240.0 5 2 0.6 4 5
F-365 hom 77 4 240.0 428 1 1 0.6 34 109 P 4 5 0 0
F-365 hom 77 2 240.0 891 2 2 0.4 35 162 P 4 5 0 0
F-365 hom 77 1 240.0 995 8 7 3.2 36 135 P 4 5 0 0
F-264 wt 80 1 240.0 9 8 4.0 4 5
F-264 wt 80 5 240.0 47 29 41.9 4 5
F-264 wt 80 5 240.0 377 22 6 11.0 36 129 P 4 5 0 0
F-264 wt 80 4 240.0 228 22 11 15.3 31 26 P 4 5 0 0
F-264 wt 80 4 240.0 0 0 0.0 4 5
F-264 wt 80 3 240.0 2 2 0.4 4 5
F-264 wt 80 3 240.0 235 17 10 15.8 31 69 P 4 5 0 0
F-264 wt 80 2 240.0 1 1 0.3 4 5
F-264 wt 80 2 240.0 286 18 9 12.8 37 47 P 4 5 0 0
F-264 wt 80 1 240.0 798 50 24 26.0 41 94 P 4 5 0 0
F-299 wt 79 1 240.0 24 18 21.1 4 5
F-299 wt 79 5 240.0 564 28 13 12.7 37 178 P 4 5 0 0
F-299 wt 79 5 240.0 4 3 1.7 4 5
F-299 wt 79 2 240.0 861 48 15 28.8 34 301 P 4 5 0 0
F-299 wt 79 2 240.0 13 12 4.8 4 5
F-299 wt 79 3 240.0 890 41 15 16.8 31 353 P 4 5 0 0
F-299 wt 79 4 240.0 13 10 12.4 4 5
F-299 wt 79 4 240.0 650 31 9 11.5 39 221 P 4 5 0 0
F-299 wt 79 3 240.0 18 15 16.0 4 5
F-299 wt 79 1 240.0 1402 32 14 14.3 29 279 P 4 5 0 0
M-320 wt 78 1 240.0 1 1 0.4 4 5
M-320 wt 78 5 240.0 10 7 6.4 4 5
M-320 wt 78 5 240.0 265 15 8 4.6 37 47 P 4 5 0 0
M-320 wt 78 4 240.0 6 5 5.2 4 5
M-320 wt 78 4 240.0 249 11 7 4.2 37 38 P 4 5 0 0
M-320 wt 78 3 240.0 310 10 7 4.7 44 25 P 4 5 0 0
M-320 wt 78 3 240.0 4 4 2.0 4 5
M-320 wt 78 2 240.0 0 0 0.0 4 5
M-320 wt 78 2 240.0 478 3 3 0.6 46 15 P 4 5 0 0
M-320 wt 78 1 240.0 286 3 3 0.8 41 8 P 4 5 0 0
M-325 wt 77 1 240.0 4 4 0.9 4 5
M-325 wt 77 5 240.0 18 13 5.7 4 5
M-325 wt 77 5 240.0 679 15 9 8.8 32 273 P 4 5 0 0
M-325 wt 77 4 240.0 4 4 0.5 4 5
M-325 wt 77 3 240.0 679 25 14 8.4 42 210 P 4 5 0 0
M-325 wt 77 3 240.0 15 12 5.8 4 5
M-325 wt 77 4 240.0 868 41 19 18.7 28 239 P 4 5 0 0
M-325 wt 77 2 240.0 6 6 2.1 4 5
M-325 wt 77 2 240.0 851 31 9 12.0 41 340 P 4 5 0 0
M-325 wt 77 1 240.0 588 11 7 4.7 42 153 P 4 5 0 0
F-340 wt 77 1 240.0 13 10 5.2 4 5
F-340 wt 77 5 240.0 367 27 11 11.9 28 152 P 4 5 0 0
F-340 wt 77 5 240.0 11 10 4.4 4 5
F-340 wt 77 4 240.0 470 17 11 10.9 32 202 P 4 5 0 0
F-340 wt 77 4 240.0 22 11 8.5 4 5
F-340 wt 77 3 240.0 552 31 15 15.2 35 191 P 4 5 0 0
F-340 wt 77 3 240.0 26 20 12.1 4 5
F-340 wt 77 2 240.0 552 24 15 14.3 45 179 P 4 5 0 0
F-340 wt 77 2 240.0 13 9 10.7 4 5
F-340 wt 77 1 240.0 776 23 14 11.4 45 202 P 4 5 0 0
M-341 wt 77 1 240.0 254 1 1 0.3 31 31 P 4 5 0 0
M-341 wt 77 5 240.0 0 0 0.0 4 5
M-341 wt 77 5 240.0 147 0 0 0.0 28 86 P 4 5 0 0
M-341 wt 77 4 240.0 0 0 0.0 4 5
M-341 wt 77 4 240.0 172 0 0 0.0 23 96 P 4 5 0 0
M-341 wt 77 3 240.0 210 0 0 0.0 26 81 P 4 5 0 0
M-341 wt 77 3 240.0 1 1 0.1 4 5
M-341 wt 77 1 240.0 0 0 0.0 4 5
M-341 wt 77 2 240.0 291 0 0 0.0 30 102 P 4 5 0 0
M-341 wt 77 2 240.0 0 0 0.0 4 5
F-353 wt 77 1 240.0 5 4 1.0 4 5
F-353 wt 77 5 240.0 141 2 2 2.3 31 53 P 4 5 0 0
F-353 wt 77 5 240.0 0 0 0.0 4 5
F-353 wt 77 4 240.0 7 5 3.6 4 5
F-353 wt 77 4 240.0 263 13 5 5.1 34 113 P 4 5 0 0
F-353 wt 77 3 240.0 239 5 2 2.0 34 87 P 4 5 0 0
F-353 wt 77 3 240.0 12 8 5.2 4 5
F-353 wt 77 2 240.0 324 3 2 2.2 31 105 P 4 5 0 0
F-353 wt 77 2 240.0 8 4 2.0 4 5
F-353 wt 77 1 240.0 513 9 6 3.9 30 104 P 4 5 0 0
M-358 wt 77 1 240.0 5 4 1.2 4 5
M-358 wt 77 5 240.0 12 11 8.0 4 5
M-358 wt 77 5 240.0 266 0 0 0.0 33 76 P 4 5 0 0
M-358 wt 77 4 240.0 135 0 0 0.0 22 22 P 4 5 0 0
M-358 wt 77 4 240.0 2 2 0.8 4 5
M-358 wt 77 3 240.0 454 2 1 0.5 36 113 P 4 5 0 0
M-358 wt 77 2 240.0 534 2 2 0.7 40 25 P 4 5 0 0
M-358 wt 77 2 240.0 7 7 4.0 4 5
M-358 wt 77 3 240.0 16 13 10.0 4 5
M-358 wt 77 1 240.0 575 5 2 2.2 40 22 P 4 5 0 0
 


Copyright 2005 by Lexicon Genetics Incorporated
Lexicon Phenotypic Analysis software version 05.05.00.05