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Open Field for Project: NIH-0824
Test Description: A large arena (40 cm x 40 cm) with infrared beams at three different levels is used to record rearing, hole poke, and locomotor activity. The animal is placed in the center and its activity is measured for 20 minutes. Data from this test is analyzed in five, 4-minute intervals. The total distance traveled (cm), vertical movement number (rearing), number of hole pokes, and the center:total distance ratio are then graphed.








Results Data
GenotypeMedian Rearing ActivityMedian Hole Poke ActivityMedian Normalized Slope**
+/+ (n=4)38.521.0-2.63
+/- (n=4)13.56.5-2.73
-/- (n=8)34.018.5-3.66
** Normalized slope is based on total distance traveled.


Genotype Mouse Label % of Total Distance Normalized
Slope
Interval 1
(4 min) 		Interval 2
(8 min) 		Interval 3
(12 min) 		Interval 4
(16 min) 		Interval 5
(20 min)
hom M-72 18.73 27.18 16.25 20.21 17.63 -0.92
hom M-73 25.78 27.88 10.99 20.5 14.84 -2.93
hom M-80 33.0 22.23 27.34 13.52 3.91 -6.69
hom M-81 18.25 33.48 16.63 14.5 17.14 -2.12
hom F-84 41.34 20.99 18.04 9.11 10.52 -7.35
hom F-86 42.77 22.62 14.76 12.3 7.56 -8.07
hom F-109 34.51 15.2 21.61 6.33 22.35 -3.32
hom F-117 30.62 23.92 14.54 16.61 14.31 -3.99
(hom)   Slope  Median:   -3.65
Mean:   -4.42
wt M-62 34.06 17.72 15.65 18.57 14.0 -3.93
wt F-77 27.28 20.28 20.91 18.66 12.86 -3.05
wt M-94 22.06 20.78 20.71 21.78 14.66 -1.38
wt F-118 30.67 17.22 15.71 16.43 19.96 -2.22
(wt)   Slope  Median:   -2.63
Mean:   -2.64
het M-71 29.28 20.78 21.86 15.09 12.99 -3.83
het M-82 21.58 24.04 20.31 17.33 16.74 -1.64
het F-85 39.1 21.88 12.65 7.37 19.01 -5.47
het F-108 21.04 10.07 28.0 28.07 12.81 0.16
(het)   Slope  Median:   -2.73
Mean:   -2.69




  Openfield New Analysis data for Project: NIH-0824 - Results        Export Data to Spreadsheet
Mouse Label Genotype Age (days) SAMPLE SAMP DUR TOTAL DIST VACTV VMOVNO V TIME STRNO CTR DIST PSA PRI SAMP DUR PRI SAMP AUX SAMP DUR AUX SAMP
M-71 het 89 1 240.0 489 11 5 4.2 38 39 P 4 5 0 0
M-71 het 89 1 240.0 2 2 0.9 P 4 5 0 0
M-71 het 89 2 240.0 0 0 0.0 P 4 5 0 0
M-71 het 89 2 240.0 347 18 6 6.5 38 0 P 4 5 0 0
M-71 het 89 3 240.0 19 14 7.7 P 4 5 0 0
M-71 het 89 4 240.0 5 3 1.7 P 4 5 0 0
M-71 het 89 5 240.0 217 0 0 0.0 33 104 P 4 5 0 0
M-71 het 89 5 240.0 11 10 4.1 P 4 5 0 0
M-71 het 89 4 240.0 252 1 1 0.0 33 84 P 4 5 0 0
M-71 het 89 3 240.0 365 4 2 2.7 39 144 P 4 5 0 0
M-82 het 89 1 240.0 0 0 0.0 P 4 5 0 0
M-82 het 89 2 240.0 606 18 10 4.7 39 101 P 4 5 0 0
M-82 het 89 1 240.0 544 28 12 8.7 35 81 P 4 5 0 0
M-82 het 89 2 240.0 0 0 0.0 P 4 5 0 0
M-82 het 89 5 240.0 422 0 0 0.0 45 97 P 4 5 0 0
M-82 het 89 5 240.0 0 0 0.0 P 4 5 0 0
M-82 het 89 4 240.0 0 0 0.0 P 4 5 0 0
M-82 het 89 4 240.0 437 10 5 1.3 41 70 P 4 5 0 0
M-82 het 89 3 240.0 512 14 7 3.0 42 151 P 4 5 0 0
M-82 het 89 3 240.0 0 0 0.0 P 4 5 0 0
F-85 het 89 1 240.0 0 0 0.0 P 4 5 0 0
F-85 het 89 1 240.0 504 2 1 0.8 35 310 P 4 5 0 0
F-85 het 89 2 240.0 282 11 5 4.5 34 141 P 4 5 0 0
F-85 het 89 5 240.0 245 2 1 1.1 33 80 P 4 5 0 0
F-85 het 89 5 240.0 0 0 0.0 P 4 5 0 0
F-85 het 89 4 240.0 95 3 1 1.1 27 59 P 4 5 0 0
F-85 het 89 4 240.0 0 0 0.0 P 4 5 0 0
F-85 het 89 3 240.0 163 8 5 5.2 36 74 P 4 5 0 0
F-85 het 89 3 240.0 0 0 0.0 P 4 5 0 0
F-85 het 89 2 240.0 0 0 0.0 P 4 5 0 0
F-108 het 89 1 240.0 284 0 0 0.0 28 100 P 4 5 0 0
F-108 het 89 1 240.0 0 0 0.0 P 4 5 0 0
F-108 het 89 2 240.0 0 0 0.0 P 4 5 0 0
F-108 het 89 5 240.0 6 3 2.8 P 4 5 0 0
F-108 het 89 5 240.0 173 2 2 1.4 28 52 P 4 5 0 0
F-108 het 89 4 240.0 11 10 8.7 P 4 5 0 0
F-108 het 89 4 240.0 379 1 1 0.3 33 113 P 4 5 0 0
F-108 het 89 3 240.0 0 0 0.0 P 4 5 0 0
F-108 het 89 3 240.0 378 1 1 0.6 31 115 P 4 5 0 0
F-108 het 89 2 240.0 136 2 2 0.9 13 3 P 4 5 0 0
M-72 hom 89 1 240.0 355 9 5 5.4 34 61 P 4 5 0 0
M-72 hom 89 2 240.0 515 42 15 18.4 38 164 P 4 5 0 0
M-72 hom 89 3 240.0 3 2 0.8 P 4 5 0 0
M-72 hom 89 5 240.0 6 3 1.2 P 4 5 0 0
M-72 hom 89 5 240.0 334 37 11 13.0 40 148 P 4 5 0 0
M-72 hom 89 4 240.0 383 31 12 14.3 38 153 P 4 5 0 0
M-72 hom 89 4 240.0 6 4 1.6 P 4 5 0 0
M-72 hom 89 2 240.0 0 0 0.0 P 4 5 0 0
M-72 hom 89 3 240.0 308 18 7 6.8 37 85 P 4 5 0 0
M-72 hom 89 1 240.0 0 0 0.0 P 4 5 0 0
M-73 hom 89 1 240.0 3 3 1.1 P 4 5 0 0
M-73 hom 89 2 240.0 1 1 0.2 P 4 5 0 0
M-73 hom 89 1 240.0 542 11 6 7.9 36 138 P 4 5 0 0
M-73 hom 89 5 240.0 1 1 0.7 P 4 5 0 0
M-73 hom 89 5 240.0 312 34 15 15.7 35 70 P 4 5 0 0
M-73 hom 89 4 240.0 431 27 8 8.9 39 53 P 4 5 0 0
M-73 hom 89 4 240.0 2 1 0.6 P 4 5 0 0
M-73 hom 89 3 240.0 231 12 8 6.8 36 63 P 4 5 0 0
M-73 hom 89 3 240.0 1 1 0.6 P 4 5 0 0
M-73 hom 89 2 240.0 586 18 8 10.1 34 93 P 4 5 0 0
M-80 hom 89 1 240.0 4 4 1.1 P 4 5 0 0
M-80 hom 89 2 240.0 0 0 0.0 P 4 5 0 0
M-80 hom 89 5 240.0 0 0 0.0 P 4 5 0 0
M-80 hom 89 5 240.0 91 6 3 2.8 32 19 P 4 5 0 0
M-80 hom 89 4 240.0 315 12 8 6.2 34 57 P 4 5 0 0
M-80 hom 89 4 240.0 2 2 0.4 P 4 5 0 0
M-80 hom 89 3 240.0 637 21 10 9.6 47 76 P 4 5 0 0
M-80 hom 89 3 240.0 4 3 2.3 P 4 5 0 0
M-80 hom 89 2 240.0 518 22 14 11.8 40 142 P 4 5 0 0
M-80 hom 89 1 240.0 769 25 16 13.2 44 127 P 4 5 0 0
M-81 hom 89 1 240.0 3 2 1.6 P 4 5 0 0
M-81 hom 89 5 240.0 233 7 4 3.1 28 82 P 4 5 0 0
M-81 hom 89 5 240.0 3 3 2.6 P 4 5 0 0
M-81 hom 89 4 240.0 15 13 5.8 P 4 5 0 0
M-81 hom 89 4 240.0 197 2 2 1.2 33 58 P 4 5 0 0
M-81 hom 89 3 240.0 226 3 1 1.5 33 16 P 4 5 0 0
M-81 hom 89 3 240.0 3 3 0.4 P 4 5 0 0
M-81 hom 89 2 240.0 455 0 0 0.0 32 70 P 4 5 0 0
M-81 hom 89 2 240.0 5 3 1.3 P 4 5 0 0
M-81 hom 89 1 240.0 248 0 0 0.0 34 22 P 4 5 0 0
F-84 hom 89 1 240.0 4 2 2.2 P 4 5 0 0
F-84 hom 89 5 240.0 4 3 2.6 P 4 5 0 0
F-84 hom 89 5 240.0 246 5 3 2.8 38 70 P 4 5 0 0
F-84 hom 89 4 240.0 213 0 0 0.0 37 82 P 4 5 0 0
F-84 hom 89 4 240.0 7 6 4.5 P 4 5 0 0
F-84 hom 89 3 240.0 6 5 2.5 P 4 5 0 0
F-84 hom 89 3 240.0 422 2 2 1.0 37 158 P 4 5 0 0
F-84 hom 89 2 240.0 491 4 2 1.3 36 175 P 4 5 0 0
F-84 hom 89 2 240.0 5 5 2.5 P 4 5 0 0
F-84 hom 89 1 240.0 967 2 2 0.8 36 273 P 4 5 0 0
F-86 hom 89 1 240.0 9 8 3.0 P 4 5 0 0
F-86 hom 89 5 240.0 126 0 0 0.0 23 108 P 4 5 0 0
F-86 hom 89 5 240.0 10 8 2.5 P 4 5 0 0
F-86 hom 89 4 240.0 205 0 0 0.0 29 129 P 4 5 0 0
F-86 hom 89 4 240.0 4 3 1.9 P 4 5 0 0
F-86 hom 89 3 240.0 246 0 0 0.0 29 172 P 4 5 0 0
F-86 hom 89 3 240.0 14 10 6.6 P 4 5 0 0
F-86 hom 89 2 240.0 377 2 1 0.5 37 185 P 4 5 0 0
F-86 hom 89 1 240.0 713 4 3 1.1 40 143 P 4 5 0 0
F-86 hom 89 2 240.0 3 3 1.2 P 4 5 0 0
F-109 hom 89 1 240.0 9 7 5.2 P 4 5 0 0
F-109 hom 89 4 240.0 0 0 0.0 P 4 5 0 0
F-109 hom 89 5 240.0 272 18 9 10.9 32 60 P 4 5 0 0
F-109 hom 89 5 240.0 0 0 0.0 P 4 5 0 0
F-109 hom 89 4 240.0 77 4 2 2.7 39 1 P 4 5 0 0
F-109 hom 89 3 240.0 10 9 7.9 P 4 5 0 0
F-109 hom 89 3 240.0 263 24 11 13.4 42 58 P 4 5 0 0
F-109 hom 89 1 240.0 420 10 5 5.0 34 151 P 4 5 0 0
F-109 hom 89 2 240.0 6 6 3.8 P 4 5 0 0
F-109 hom 89 2 240.0 185 4 2 1.5 45 68 P 4 5 0 0
F-117 hom 89 1 240.0 3 3 0.7 P 4 5 0 0
F-117 hom 89 1 240.0 946 11 7 7.5 36 161 P 4 5 0 0
F-117 hom 89 5 240.0 442 18 7 7.6 47 37 P 4 5 0 0
F-117 hom 89 5 240.0 4 4 2.2 P 4 5 0 0
F-117 hom 89 4 240.0 513 17 10 10.6 36 49 P 4 5 0 0
F-117 hom 89 4 240.0 4 4 2.1 P 4 5 0 0
F-117 hom 89 3 240.0 449 12 7 8.4 40 88 P 4 5 0 0
F-117 hom 89 3 240.0 3 3 0.7 P 4 5 0 0
F-117 hom 89 2 240.0 739 18 8 10.8 40 62 P 4 5 0 0
F-117 hom 89 2 240.0 2 2 0.9 P 4 5 0 0
M-62 wt 91 1 240.0 1 1 0.1 P 4 5 0 0
M-62 wt 91 1 240.0 640 23 11 9.7 47 116 P 4 5 0 0
M-62 wt 91 4 240.0 6 6 2.1 P 4 5 0 0
M-62 wt 91 5 240.0 263 32 11 10.6 26 146 P 4 5 0 0
M-62 wt 91 5 240.0 2 2 0.9 P 4 5 0 0
M-62 wt 91 4 240.0 349 12 5 4.5 38 192 P 4 5 0 0
M-62 wt 91 3 240.0 294 5 3 3.1 36 86 P 4 5 0 0
M-62 wt 91 3 240.0 3 3 0.3 P 4 5 0 0
M-62 wt 91 2 240.0 333 15 7 5.7 36 130 P 4 5 0 0
M-62 wt 91 2 240.0 1 1 0.1 P 4 5 0 0
F-77 wt 89 1 240.0 19 14 9.9 P 4 5 0 0
F-77 wt 89 1 240.0 861 10 5 5.4 41 324 P 4 5 0 0
F-77 wt 89 2 240.0 7 5 2.4 P 4 5 0 0
F-77 wt 89 5 240.0 5 3 2.6 P 4 5 0 0
F-77 wt 89 5 240.0 406 15 6 6.5 37 182 P 4 5 0 0
F-77 wt 89 4 240.0 589 25 11 9.6 32 210 P 4 5 0 0
F-77 wt 89 4 240.0 10 8 5.4 P 4 5 0 0
F-77 wt 89 3 240.0 17 14 10.5 P 4 5 0 0
F-77 wt 89 3 240.0 660 18 8 10.3 41 248 P 4 5 0 0
F-77 wt 89 2 240.0 640 24 10 9.8 37 299 P 4 5 0 0
M-94 wt 89 1 240.0 2 2 0.6 P 4 5 0 0
M-94 wt 89 2 240.0 292 15 6 8.7 44 83 P 4 5 0 0
M-94 wt 89 1 240.0 310 17 6 8.9 44 84 P 4 5 0 0
M-94 wt 89 2 240.0 1 1 0.3 P 4 5 0 0
M-94 wt 89 3 240.0 3 3 1.3 P 4 5 0 0
M-94 wt 89 5 240.0 206 5 3 2.1 31 30 P 4 5 0 0
M-94 wt 89 5 240.0 0 0 0.0 P 4 5 0 0
M-94 wt 89 4 240.0 9 8 3.3 P 4 5 0 0
M-94 wt 89 4 240.0 306 18 4 6.2 40 99 P 4 5 0 0
M-94 wt 89 3 240.0 291 27 10 13.2 40 70 P 4 5 0 0
F-118 wt 89 1 240.0 8 6 5.8 P 4 5 0 0
F-118 wt 89 1 240.0 773 15 9 7.9 39 108 P 4 5 0 0
F-118 wt 89 5 240.0 10 8 5.0 P 4 5 0 0
F-118 wt 89 5 240.0 503 25 14 7.9 43 163 P 4 5 0 0
F-118 wt 89 4 240.0 414 24 11 7.6 39 139 P 4 5 0 0
F-118 wt 89 4 240.0 5 4 1.6 P 4 5 0 0
F-118 wt 89 3 240.0 5 5 4.8 P 4 5 0 0
F-118 wt 89 3 240.0 396 29 16 7.7 38 66 P 4 5 0 0
F-118 wt 89 2 240.0 7 5 2.5 P 4 5 0 0
F-118 wt 89 2 240.0 434 19 12 6.6 40 47 P 4 5 0 0
 


Copyright 2005 by Lexicon Genetics Incorporated
Lexicon Phenotypic Analysis software version 05.05.00.05